G protein-coupled receptors | G protein signaling, arrestin recruitment | Secretion, tumorigenesis | Abboud | Dayana | | University of Liege | Belgium | | | | | | | | | | | | | | | | | |
Class C GPCRs | | | Acher | Francine | | University of Paris/CNRS | France | | | | | | | | | | | | | | | | | |
Adrenergic receptors, GnRHR, GPR54, LHCGR, FSHR | | Mitochondrial dynamics, fertilization, reproductive hormones homeostasis | Andric | Silvana | | University of Novi Sad Faculty of Sciences | Serbia | | | | | | | | | | | | | | | | | |
TASR | Bitter compounds AND TAS2R | Enterohormone secretion | Ardevol | Anna | | Universitat Rovira i Virgili | Spain | | | | | | | | | | | | | | | | | |
Food proteins, receptor proteins that sense food/nutrients | Receptors/transporters that sense nutrients in the human gastrointestinal tract | Endocrine system, intestinal system, GPCR responses, intestinal responses | Bastiaan-Net | Shanna | | Wageningen UR; Food & Biobased Research | Netherlands | | | | | | | | | | | | | | | | | |
GPCRs | G protein-arrestin dichotomy | Second messenger production, cell morphological changes, receptor desensitization | Benkel | Tobias | | University of Bonn | Germany | | | | | | | | | | | | | | | | | |
MC4R | Gs, Gq; G12/13, MRAP2 | | Biebermann | Heike | | Charite University Medicine Berlin | Germany | | | | | | | | | | | | | | | | | |
Orphan GPCRs such as GPR160, GPR141 | G protein pathways | cAMP, FRET | Birgul | Necla | | University of Bogazici | Turkey | | | | | | | | | | | | | | | | | |
Sonic Hedgehog | Hedgehog signaling pathway. Proteins: Sonic Hedgehog, Smoothened, Patched | Expression of GLI transcription factor | Blanco-Canosa | Juan Bautista | | Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) | Spain | | | | | | | | | | | | | | | | | |
GPCR (LHR, FSHR, OXTR, Vasopressin R, MTR) | cAMP, IP3, beta-arrestin, Calcium, EPAC | Steroid secretion | Bozon | Veronique | | INRAe and University of Tours | France | | | | | | | | | | | | | | | | | |
Leukotriene and ghrelin receptors | | | Catoire | Laurent | | CNRS/University of Paris | France | | | | | | | | | | | | | | | | | |
Class A GPCRs | Biased signaling | Biased signaling | Chabbert | Marie | | CNRS | France | | | | | | | | | | | | | | | | | |
Opioid Receptors, RGS proteins, Arrestins, Spinophilin | Novel Signaling Pathways of Opioid Receptors- Role of interactive proteins | Receptor activation, Desensitization, Autophagy, Endosomal signaling | Georgoussi | Zafiroula (Iro) | | Institute of Biosciences and Applications/National Centre for Scientific Research "Demokritos" | Greece | | | | | | | | | | | | | | | | | |
OXTR, AVPRs, CB2R, KOR | IP1, cAMP, Ca2+ | Proliferation, immune function | Gruber | Christian | | Medical University of Vienna | Austria | | | | | | | | | | | | | | | | | |
Neuropsychiatric GPCRs, Class B1, G proteins | Generally GPCR-G protein interface | G protein activation and Arrestin recruitment | Hauser | Alexander | | University of Denmark | Denmark | | | | | | | | | | | | | | | | | |
G-protein molecules | Arachidonic acid pathway | Inflammatory cells | Hoxha | Malvina | | Catholic University Our Lady of Good Counsel | Albania | | | | | | | | | | | | | | | | | |
G-protein coupled receptors | G-protein, arrestin | G-protein activation | Hunyady | Laszlo | | Research Centre for Natural Sciences | Hungary | | | | | | | | | | | | | | | | | |
GPCRs, Adenylate cyclase, PKA, phosphodiesterase, beta-arrestin, GRKs | Gs/cAMP/PKA, beta-Arrestin-GPCR interaction, GRKs | cAMP, PKA, gene expression, steroidogenesis | Jean-Alphonse | Frederic | | CNRS | France | | | | | | | | | | | | | | | | | |
GPR37, Muscarinic Aceytlcholine Receptors, G proteins, proteins involved in autophagy and mitophagy, including ATG3 | Pathways and proteins related to the proteins listed above | Autophagy and mitophagy, inflammation | Kan | Beki | | Acibadem University | Turkey | | | | | | | | | | | | | | | | | |
GPR120; GPR21; CXCR4 | | | Kinsella | Gemma | | TU Dublin | Ireland | | | | | | | | | | | | | | | | | |
Beta2AR, M2,3AR, OXRs, PTH1R, opioids, CXCRs | G proteins, arrestins, GRKs | | Kolb | Peter | | Philipps-University Marburg | Germany | | | | | | | | | | | | | | | | | |
Membrane proteins (Adenosine receptors, P2X7, MmpL3, viroporins) | GPCR-Gi or arrestin | Any | Kolocouris | Antonios | | National and Kapodistrian University of Athens, Pharmacy | Greece | | | | | | | | | | | | | | | | | |
Muscarinic (M1,2,4), dopaminergic (D2,3) and melanocortin (MC4) receptors | G-protein coupled pathway | cAMP response | Laasfeld | Tonis | | University of Tartu | Estonia | | | | | | | | | | | | | | | | | |
Class B GPCRs | cAMP-dependent pathway, peptide-protein interactions | Regulation of gene expression | Latek | Dorota | | University of Warsaw | Poland | | | | | | | | | | | | | | | | | |
Adhesion GPCRs (especially family ADGRG), CMKLR1, PAR, Y receptor | | | Liessmann | Fabian | | Institute for Drug Discovery | Germany | | | | | | | | | | | | | | | | | |
GHSR-1a | Interaction with intra-cellular partner : G-protein, beta-Arrestin, regulatory proteins | | Louet | Maxime | | University of Montpellier | France | | | | | | | | | | | | | | | | | |
Purine receptors, orphan GPCRs | G protein signaling (all pathways), beta-arrestin translocation, new signaling paradigms | cAMP, Ca2+, beta-arrestin recruitment, microscopically visible changes | Mueller | Christa | | University of Bonn | Germany | | | | | | | | | | | | | | | | | |
GPCRs, RAMPs | GPCR-RAMP | Beta-arrestin, cAMP | Nemec | Katarina | | MDC Berlin | Germany | | | | | | | | | | | | | | | | | |
AT1R, TXA2R | AT1R - TXA2R Heterodimerization | FRET | Olgac | Abdurrahman | | Gazi University | Turkey | | | | | | | | | | | | | | | | | |
Orphan GPCRs (GPR37), Chemokine receptors, Spingosine 1 phosphate receptors | MAPK, Autophagy pathway, Atg3 protein interaction partners | Autophagy, cellular metabolism (mitochondria), Endosomal trafficking | Oz-Arslan | Devrim | | Acibadem University | Turkey | | | | | | | | | | | | | | | | | |
Muscarinic and dopaminergic receptors | Physiological role of voltage dependence of GPCRs | | Parnas | Moshe | | Tel Aviv University | Israel | | | | | | | | | | | | | | | | | |
Viral GPCRs | Gq signaling, G12/13 signaling, Hippo signaling | Calcium mobilisation, cell proliferation, cancer growth | Pfeil | Eva | | Vrije Universiteit Amsterdam | Netherlands | | | | | | | | | | | | | | | | | |
GPCRs (chemokine receptors, especially CXCR3), arrestins, G proteins | Arrestin-mediated signaling | | Rajagopal | Sudarshan | | Duke University School of Medicine | USA | | | | | | | | | | | | | | | | | |
GPCR (muscarinic, dopamine, melanocortine, NP Y, LH, FSH, Fzl), sigma1 receptor, G(alpha) | Ligand binding (also big, protein type ligands), receptor-G protein interactions (subtype selectivity) | Activation/inhibition of cAMP (response to measure for all G proteins (using modified proteins)) | Rinken | Ago | | University of Tartu | Estonia | | | | | | | | | | | | | | | | | |
M1 muscarinic acetylcholine receptor | GPCR phosphorylation-mediated pathways | | Scarpa | Miriam | | University of Glasgow | United Kingdom | | | | | | | | | | | | | | | | | |
CXCR4 and ACKR3 | G proteins and beta-arrestins | Migration | Schlecht | Geraldine | | University Paris-Saclay | France | | | | | | | | | | | | | | | | | |
Atypical Chemokine Receptors (ACKRs) | Signaling by ACKRs | Cell migration | Thelen | Marcus | | Institute for Research in Biomedicine, Universita della Svizzera Italiana | Switzerland | | | | | | | | | | | | | | | | | |
BRAF, CRAF, NRAS, KSR, MEK, ERK, DUSP6, MDM2, MDM4, p53, eIF4A, eIF4F, mTOR, LAMTOR | ERK MAPK (RAS/RAF/MEK/ERK), BRAF-KSR, CRAF-KSR, BRAF-AMPK, CRAF-AMPK, MDM2-MDM4 | Proliferation, apoptosis, necroptosis, glycolysis, oxidative phosphorylation/mitochondrial respiration | Uldrijan | Stjepan | | Masaryk University | Czech Republic | | | | | | | | | | | | | | | | | |
GPCRs | | | Vanden Broeck | Jozef | | KU Leuven | Belgium | | | | | | | | | | | | | | | | | |
Cell surface receptors of natural killer cells and other lymphocytes, and their ligands | Activation/inhibition of NK cell cytotoxicity, interactions of NK cell receptors with their protein ligands | NK cell or cytotoxic T cell response to cancer, i.e., killing of tumour cells | Vanek | Ondrej | | Charles University, Faculty of Science | Czech Republic | | | | | | | | | | | | | | | | | |
Adrenergic receptors, free fatty acid receptors (FFARs), lactate receptors, adhesion GPCRs (GPR56, latrophilins) | Calcium, cAMP signals, etc. | Metabolism, exocytosis, morphology | Vardjan | Nina | | University of Ljubljana, Faculty of Medicine | Slovenia | | | | | | | | | | | | | | | | | |
Sigma-1 chaperone protein | Sigma-1 chaperone AND GABA-B receptor | | Vavers | Edijs | | Latvian Institute of Organic Synthesis | Latvia | | | | | | | | | | | | | | | | | |
Arrestins | G-protein-mediated signaling | | Vrecl | Milka | | University of Ljubljana | Slovenia | | | | | | | | | | | | | | | | | |
GPCRs with biased ligands; angiotensin receptor; chemokine receptors | | | Wingler | Laura | | Duke University | United States | | | | | | | | | | | | | | | | | |
Cystatins, stefins, protease inhibitors | | Proteostasis | Zerovnik | Eva | | Josef Stefan Institute | Slovenia | | | | | | | | | | | | | | | | | |
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