Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Downstream signal transduction pathways;Downstream cellular responses Cell/Tissue culture experiments;In vivo animal experiments Structure-based investigations;Data science and/or ML/AI;Clinical/Translational studies;Optophysiological experiments;Electrophysiological experiments No Abboud Dayana *protected email* University of Liege Belgium
Ligand-receptor interactions (cell culture systems) Structure-based investigations No Acher Francine *protected email* University of Paris / CNRS France
Downstream signal transduction pathways;Downstream cellular responses;in vivo models Structure complexes;Ligand-receptor interactions (cell culture systems) Cell/Tissue culture experiments;In vivo animal experiments Structure-based investigations;Data science and/or ML/AI;Electrophysiological experiments No Andric Silvana *protected email* University of Novi Sad Faculty of Sciences Serbia
Ligand-receptor interactions (cell culture systems) Structure complexes;Downstream signal transduction pathways Cell/Tissue culture experiments;In vivo animal experiments Structure-based investigations;Clinical/Translational studies No Ardevol Anna *protected email* Universitat Rovira i Virgili Spain
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Cell/Tissue culture experiments Structure-based investigations;Data science and/or ML/AI;In vivo animal experiments No Bastiaan-Net Shanna *protected email* Wageningen UR; Food & Biobased Research Netherlands
Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Ligand-receptor interactions (cell culture systems) Cell/Tissue culture experiments Structure-based investigations;In vivo animal experiments No Benkel Tobias *protected email* University of Bonn Germany
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways Structure complexes;Downstream cellular responses Cell/Tissue culture experiments Structure-based investigations No Biebermann Heike *protected email* Charité University medicine Berlin Germany
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways Structure complexes;Downstream signal transduction pathways Cell/Tissue culture experiments Structure-based investigations;Electrophysiological experiments No Birgul Necla *protected email* University of Bogazici Turkey
Chemistry and mass spectrometry of proteins Downstream signal transduction pathways;Downstream cellular responses;phage display Chemical synthesis of peptide/protein ligands with posttranslational modifications Yes The study of the Sonic Hedgehog protein and its network interactions and development of peptide binders (antagonists) by phage display. Blanco-Canosa Juan Bautista *protected email* Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) Spain
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways Cell/Tissue culture experiments Cell/Tissue culture experiments No Bozon Veronique *protected email* INRAe and University of Tours France
Conformational ensembles/landscapes and kinetic barriers in GPCRs & kinetics of interactions between ligands/effectors and GPCRs Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses In vitro studies of GPCR energy landscape in lipid bilayers (nanodiscs) by NMR & study of kinetics of interations between ligands/effectors and GPCRs by single molecule force spectroscopy Cell/Tissue culture experiments;Optophysiological experiments Yes Our research is aimed at gaining insight into GPCR energy landscapes in complement to the plethora of 3D atomic structures available. In particular, we are interested by the allosteric regulation of the activation of GPCRs by the membrane/lipids. Solution-state NMR and single molecule force spectroscopies are the techniques we are currently using to study receptors embedded in lipid nanodiscs. For a given receptor, we would be interested by a collaboration that could help us to determine in which kind of membrane(s) (and lipids) that receptor could be preferentially localized and how a modification of the lipid composition can affect its activity. Catoire Laurent *protected email* CNRS/University of Paris France
Dynamics of complexes Structure-based investigations Structure-based investigations No Chabbert Marie *protected email* CNRS France
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Downstream signal transduction pathways;Downstream cellular responses Cell/Tissue culture experiments;Mutagenesis, receptor Pharmacology In vivo animal experiments;Optophysiological experiments;Electrophysiological experiments Yes Define the role of Autophagy in Neurogenerative diseases. Investigate Endosomal Signaling of GPCRs. Novel Interactive proteins of GPCRs and their involvement in physiology. Georgoussi Zafiroula (Iro) *protected email* Institute of Biosciences and Applications/National Centre for Scientific Research "Demokritos" Greece
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Downstream cellular responses Cell/Tissue culture experiments Structure-based investigations;Data science and/or ML/AI Yes Gruber Christian *protected email* Medical University of Vienna Austria
Data science methods and integration of diverse datasets Downstream signal transduction pathways;Downstream cellular responses Data science and/or ML/AI;Clinical/Translational studies Cell/Tissue culture experiments;Clinical/Translational studies;Optophysiological experiments;Electrophysiological experiments No Hauser Alexander *protected email* University of Denmark Denmark
Downstream signal transduction pathways Downstream signal transduction pathways Structure-based investigations;Data science and/or ML/AI;Clinical/Translational studies Structure-based investigations;Data science and/or ML/AI;Clinical/Translational studies No Hoxha Malvina *protected email* Catholic University Our Lady of Good Counsel Albania
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways Ligand-receptor interactions (cell culture systems) Cell/Tissue culture experiments No Hunyady Laszlo *protected email* Research Centre for Natural Sciences Hungary
Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Cell/Tissue culture experiments Structure-based investigations;In vivo animal experiments No Jean-Alphonse Frederic *protected email* CNRS France
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Cell/Tissue culture experiments;Clinical/Translational studies;Electrophysiological experiments Structure-based investigations;Data science and/or ML/AI;In vivo animal experiments;Clinical/Translational studies;FRET, BRET Yes Planning : interaction between GPR 37 and cell death Kan Beki *protected email* Acibadem University Turkey
Ligand-receptor interactions (cell culture systems) Structure complexes;Downstream signal transduction pathways;Downstream cellular responses Molecular modelling; virtual screening; protein engineering Clinical/Translational studies Kinsella Gemma *protected email* TU Dublin Ireland
Structure complexes Downstream signal transduction pathways Data science and/or ML/AI Cell/Tissue culture experiments No Kolb Peter *protected email* Philipps-University Marburg Germany
Structure complexes Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses;Structural biology Structure-based investigations Cell/Tissue culture experiments;In vivo animal experiments Yes Development of ligands targeting adenosine receptors, Development of ligands targeting dimerization of adenosine receptors, Development of ligands targeting P2X7Rs Kolocouris Antonios *protected email* National and Kapodistrian University of Athens, Pharmacy Greece
Ligand-receptor interactions (cell culture systems) Structure complexes Data science and/or ML/AI;Image analysis Structure-based investigations;In vivo animal experiments No Laasfeld Tonis *protected email* University of Tartu Estonia
Structure complexes;Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Structure-based investigations;Data science and/or ML/AI Cell/Tissue culture experiments;In vivo animal experiments;Clinical/Translational studies Yes Animal research facility Latek Dorota *protected email* University of Warsaw Poland
Ligand-receptor interactions (cell culture systems) Structure-based investigations;Data science and/or ML/AI No Liessmann Fabian *protected email* Institute for Drug Discovery Germany
Structure complexes Structure complexes;Ligand-receptor interactions (cell culture systems) Structure-based investigations Structure-based investigations No Louet Maxime *protected email* University of Montpellier France
Structure complexes;Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;development and providing tool compounds Animal studies Cell/Tissue culture experiments;Structure-based investigations;chemical synthesis of small molecules In vivo animal experiments;Clinical/Translational studies;Electrophysiological experiments Yes In vivo studies - different animal models in inflammatory diseases, neurodegenerative diseases, cancer, immunotherapy of cancer and infection Mueller Christa *protected email* University of Bonn Germany
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Structure complexes Cell/Tissue culture experiments Structure-based investigations;Data science and/or ML/AI;In vivo animal experiments;Clinical/Translational studies No Nemec Katarina *protected email* MDC Berlin Germany
Structure complexes Structure complexes;Ligand-receptor interactions (cell culture systems) Structure-based investigations Cell/Tissue culture experiments;Structure-based investigations No Olgac Abdurrahman *protected email* Gazi University Turkey
Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Ligand-receptor interactions (cell culture systems) Cell/Tissue culture experiments;In vivo animal experiments Structure-based investigations;Data science and/or ML/AI;Clinical/Translational studies No Oz-Arslan Devrim *protected email* Acibadem University Turkey
Downstream cellular responses;physiological role - effect on behavior In vivo animal experiments;Electrophysiological experiments No Parnas Moshe *protected email* Tel Aviv University Israel
Downstream signal transduction pathways Downstream cellular responses Cell/Tissue culture experiments Cell/Tissue culture experiments;Structure-based investigations No Pfeil Eva *protected email* Vrije Universiteit Amsterdam Netherlands
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses Cell/Tissue culture experiments;In vivo animal experiments Structure-based investigations;Data science and/or ML/AI No Rajagopal Sudarshan *protected email* Duke University School of Medicine USA
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways Structure complexes;Downstream cellular responses Cell/Tissue culture experiments Structure-based investigations;Clinical/Translational studies Yes Projects, where we can implement our ultrasensitive assay system, which enables to characterize intermolecular interactions with single molecule sensitivity and assay systems where multiple fluorescent proteins and other players have to be expressed in the same cells and their network has to be studied. And development of assay systems for screening of clinical samples. Rinken Ago *protected email* University of Tartu Estonia
Physiological and behavioural responses Structure complexes;Ligand-receptor interactions (cell culture systems) Cell/Tissue culture experiments;In vivo animal experiments Cell/Tissue culture experiments;Structure-based investigations Scarpa Miriam *protected email* University of Glasgow United Kingdom
Downstream cellular responses;In vivo and skin organoid models Cell/Tissue culture experiments;In vivo animal experiments;Clinical/Translational studies Structure-based investigations;Data science and/or ML/AI;Optophysiological experiments No Schlecht Geraldine *protected email* University Paris-Saclay France
No Thelen Marcus *protected email* Institute for Research in Biomedicine, Universita della Svizzera Italiana Switzerland
Downstream signal transduction pathways;Downstream cellular responses Structure complexes;Downstream signal transduction pathways Cell/Tissue culture experiments Structure-based investigations;In vivo animal experiments No Uldrijan Stjepan *protected email* Masaryk University Czech Republic
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways;Downstream cellular responses;RNAi in vivo (insects) Structure complexes;Downstream signal transduction pathways;Downstream cellular responses Cell/Tissue culture experiments;in vivo RNAi (insects) Structure-based investigations;Data science and/or ML/AI;Optophysiological experiments;Electrophysiological experiments Yes We are interested in GPCR signaling & evolution and happy to join any initiatives including GPCR studies and applications involving arthropods/insect (pests) Vanden Broeck Jozef *protected email* KU Leuven Belgium
Structure complexes;Ligand-receptor interactions (cell culture systems) Structure complexes;Ligand-receptor interactions (cell culture systems) Structure-based investigations;Production of recombinant glycoproteins in human cell line with defined glycosylation state for X-ray crystallography, or isotope-labelled for NMR Cell/Tissue culture experiments;Structure-based investigations No Vanek Ondrej *protected email* Charles University, Faculty of Science Czech Republic
Downstream signal transduction pathways;Downstream cellular responses Ligand-receptor interactions (cell culture systems) Cell/Tissue culture experiments;Optophysiological experiments;Electrophysiological experiments In vivo animal experiments;Clinical/Translational studies No Vardjan Nina *protected email* University of Ljubljana, Faculty of Medicine Slovenia
Ligand-receptor interactions (cell culture systems) Downstream signal transduction pathways In vivo animal experiments Electrophysiological experiments No Vavers Edijs *protected email* Latvian Institute of Organic Synthesis Latvia
Ligand-receptor interactions (cell culture systems);Downstream signal transduction pathways Structure complexes Cell/Tissue culture experiments;In vivo animal experiments;Electrophysiological experiments Structure-based investigations;Data science and/or ML/AI No Vrecl Milka *protected email* University of Ljubljana Slovenia
Structure complexes;Ligand-receptor interactions (cell culture systems) Structure complexes;Downstream signal transduction pathways;Downstream cellular responses Cell/Tissue culture experiments;Structure-based investigations Data science and/or ML/AI;In vivo animal experiments;Clinical/Translational studies No Wingler Laura *protected email* Duke University United States
Downstream signal transduction pathways Structure complexes;Downstream signal transduction pathways;protein aggregation and condensation Electrophysiological experiments Yes Downstream effects of protein aggregation, membranes perforation Zerovnik Eva *protected email* Josef Stefan institute Slovenia
