Member List

NameCountryWGERC code Techniques of expertise Connected keyword of expertise Research interests
Cordomí Arnau
Universitat Autònoma de Barcelona
ESWG1, WG31. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Structural
  • Chemistry
  • Biophysical
1. EPR and Fluorescence spectroscopy
2. GPCR and transducer purification
3. X-ray crystallography
1. dimers
2. signaling complexes
3. signal transduction
Dr. Daniel Hilger
Philipps-Universität Marburg
DEWG1, WG31. Molecular biophysics
2. Biochemistry
3. Structural biology and its methodologies
  • Biophysical
  • Biochemical
  • Structural

1. Electron paramagnetic resonance
2. Protein purification
3. Crystallography
1. Structure and dynamics of GPCRs and their complexes
2. Molecular basis of GPCR-mediated signaling
3. Drug development
Tikhonova, Irina
Queen's University Belfast
Website
GBWG1, WG3, WG51. Computational biology
2. Fundamental aspects of synthetic biology and chemical biology
3. Biochemistry
  • Computational
  • Biochemical
  • Pharmacology

1. MD simulations
2. Virtual screening
3. Structure-function
1. Allosteric sites
2. Dimerization
3. Drug design
Gmeiner, Peter
FAU
Website
DEWG31. Medicinal chemistry
2. Neurological disorders
3. Imaging for medical diagnosis
  • Chemistry
  • Pharmacology
  • Computational

1. Synthesis
2. In vitro assays
3. Molecular dynamics
1. GPCR ligands
2. Drug discovery
3. Structure based design
Kolb, Peter
Philipps-University Marburg
Website
DEWG3, WG51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Pharmacology

1. Docking
2. Homology modelling
1. Ligand selectivity
2. Prediction of affinity/efficacy/bias
3. Chemical universe
Rafael Franco
Universitat de Barcelona
ESWG1, WG21. Biological chemistry
2. Biochemistry
3. Neural cell function, communication and signalling, neurotransmission
  • Biochemical
  • Pharmacology
  • Biophysical
Di Pizio Antonella
Leibniz-Institute for Food Systems Biology at TUM
Website
DEwg1, wg3 1. Food sciences
2. Food sciences
3. Medicinal chemistry
  • Computational
  • Structural
  • Chemistry
Abatematteo Francesca Serena
University of Bari Aldo Moro
Website
ITwg3, wg41. Medicinal chemistry
2. Medicinal chemistry
3. Biological chemistry
  • Chemistry
  • Pharmacology
  • Computational
1. GPCRS
2. CB2
3.
Sztyler Agnieszka
Charité Medical University Berlin
Website
DEwg1, wg2, wg3 1. Biochemistry
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Biophysical
  • Structural
1. Fluorescence spectroscopy
1. GPCR
2. arrestin
3. signal transduction
Hauser, Alexander
University of Copenhagen
DKWG1, WG2, WG3, WG4, WG51. Bioinformatics
2. Systems biology
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Computational
  • Structural
  • Biophysical

1. Data science
2. Structure analysis
1. GPCRs
2. Pharmacogenomics
3. Structure Biology
Tobin, Andrew
University of Glasgow
GBWG21. Cell signalling and signal transduction
2. Neural cell function, communication and signalling, neurotransmission
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biochemical
  • Pharmacology
  • Cell biology

1. Neuroscience
2. Gut physiology
3. Respiratory disease
Rinken Ago
University of Tartu
Website
EEwg1, wg3, wg4 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Neural cell function, communication and signalling, neurotransmission
  • Pharmacology
  • Biophysical
  • Biochemical
1. Ligand binding properties
2. Superresolution microscopy for receptors
3. Fluorescent probes for receptors
1. kinetic mechanism of ligand binding
2. Regulation of ligand binding and signal transduction
3. Novel methods for receptor research
Shahraki Aida
Philipps-University Marburg
DEwg11. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Computational biology
  • Computational
  • Structural
  • Pharmacology
1. high-throughput virtual screening
2. peptide-based agonists
3. structural studies
Isbilir Ali
Max Delbrück Center for Molecular Medicine
DEwg1, wg2, wg3, wg4 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Molecular aspects of endocrinology
  • Pharmacology
  • Cell biology
  • Biophysical
1. Microscopy
2. Multiplexed
3. Biased
Mamyrbekov Alibek
University of Copenhagen
DKwg51. Bioinformatics
2. Bioinformatics
3. Scientific computing, simulation and modelling tools
  • Computational
  • Computational
  • Computational
Kliewer Andrea
University Hospital Jena
DEwg2, wg3, wg41. Neural bases of behaviour
2. Neural bases of behaviour
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Behavioral
  • Pharmacology
  • Animal models
1. pain/addiction behavior
2. opioids
3. genetic opioid receptor models
1.
2.
3.
Bock Andreas
Max-Delbrueck-Center for Molecular Medicine
Website
DEwg1, wg2, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Pharmacology
  • Biochemical
  • Biophysical
1. G protein-coupled receptors
2. cyclic nucleotides
3. FRET
1. Compartmentalization
2. G protein-coupled receptors
3. Biomolecular condensates
Chevigné Andy
Luxembourg Institute of Health
LUwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Cell biology
  • Pharmacology
  • Structural
1. GPCR
2. Chemokine
3. signaling
ALMERICO ANNA MARIA
University of Palermo
Website
ITwg1, wg3, wg4 1. Method development in chemistry
2. Method development in chemistry
3. Bioinformatics
  • Computational
  • Chemistry
  • Biochemical
1. molecular modelling
2. synthesis and drug design
3. mechanism of action of new drugs
1. drug design and synthesis
2. QSAR and SAR analysis
3. antitumor/antivirus/antimicrobial agents
Kan Beki
Acibadem Mehmet Ali Aydinlar University
TRwg1, wg21. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Cell death (including senescence) and autophagy
  • Biochemical
  • Cell biology
  • Biophysical
1. Signal transduction cascades, second messengers

3. protein structure and function
1. GPCR signaling and G proteins
2. Neurodegeneration
3. Autophagy and mitophagy
Haran Tali
Technion
ILwg11. Molecular architecture and structure
2. Molecular architecture and structure
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Biophysical
  • Structural
  • Computational
1. Affinity and stability measurements
2. Flexibility measurements
3. Analysis of NGS data
1. Protein-DNA interactions
2. P53 functionality
3. Gene regulation
Bondar Alexey
Center for Nanobiology and Structural Biology
CZwg1, wg2, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Biophysical
  • Cell biology
  • Biochemical
1. clathrin
2. single-molecule imaging
3. preassembly
Xu Bo
uppsala university
SEwg1, wg2, wg3, wg41. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Cell signalling and signal transduction
3. 12. Applied Life Sciences and Biotechnology
  • Pharmacology
  • Cell biology
  • Biochemical
1. in vitro pharmacology
2. cell culture and transfection
3. in situ proximity ligation assay
1. signalling pathway
2. GPCR
3. biosensor development
Brkljačić Jelena
Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade
Website
RSwg2, wg31. Molecular aspects of endocrinology
2. Molecular aspects of endocrinology
3. Metabolism, biological basis of metabolism-related disorders
  • Biochemical
  • Biochemical
  • Animal models
1. Glucocorticoid receptor
2. Redox signalling
3. Metabolic disorders
Rosano Camillo
IRCCS Policlinico San Martino - Genova (I)
ITwg1, wg2, wg3, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Scientific computing, simulation and modelling tools
  • Structural
  • Computational
  • Biochemical
1. Crystallography
2. Molecular Simulations
1. Oncology
2. Drug Design
3.
Cevheroglu Orkun
Ankara University
Website
TRwg1, wg2, wg3, wg41. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Cell signalling and signal transduction
  • Biochemical
  • Cell biology
  • Biophysical
1. BRET
2. FRET
3. BiFC
de Graaf Chris
Sosei Heptares
Website
GBwg1, wg2, wg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Computational
  • Chemistry
  • Structural
1. Cheminformatics
2. Computational Medicinal Chemistry
3. Structure-Based Drug Discovery
1. G Protein-Coupled Receptors
2. Computer-Aided Drug Design
3. Structural Bioinformatics
Munk Christian
Copenhagen University
Website
DKwg51. Bioinformatics
2. Bioinformatics
3. Machine learning
  • Computational
  • Computational
  • Computational
1. GPCRs
2. Biased signalling
3. Structure analysis
MOREAU Christophe
CNRS
FRwg41. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds)
2. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds)
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Biophysical
  • Biochemical
  • Biochemical
1. electrophysiology
2. protein engineering
3. Ion channel-coupled receptor
1. electrical bionsensors
2. GPCRs
3. ion channel reporter
Bonnesen Cecilie
University of Copenhagen
DKwg1, wg2, wg3, wg4 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3.
  • Structural
  • Structural
  • Biochemical
Maccallini Cristina
University G. d'Annunzio of Chieti-Pescara
ITwg3, wg4 1. Medicinal chemistry
2. Medicinal chemistry
3. Analytical chemistry
  • Chemistry
  • Biochemical
  • Pharmacology
1. Synthesis
2. enzyme inhibition
3. nitric oxide
1. Synthesis
2. small molecules
3. nitric oxide
Goudet Cyril
Institut de Genomique Fonctionnelle
Website
FRwg11. Neural cell function, communication and signalling, neurotransmission
2. Neural cell function, communication and signalling, neurotransmission
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Pharmacology
  • Animal models
1. Neuropharmacology
2. Photopharmacology
3. Chronic pain
1. GPCR
2. Pain
3. Neuromodulation
Calebiro Davide
University of Birmingham
Website
GBwg1, wg2, wg3, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Molecular aspects of endocrinology
  • Biophysical
  • Pharmacology
  • Computational
1. single-molecule microscopy
2. FRET
3. quantitative biology
1. GPCRs
2. cAMP
3. signal compartmentalization
van der Es Daan
Leiden University
falsewg31. Organic chemistry
2. Organic chemistry
3. Biological chemistry
  • Chemistry
  • Chemistry
  • Chemistry
1. Organic Synthesis
2. Chemical Biology
3. Molecular Probes
Abboud Dayana
University of liege
BEwg1, wg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Metabolism, biological basis of metabolism-related disorders
  • Pharmacology
  • Animal models
  • Biochemical
1. GPCR
2. Orphan GPCR
3. Signal transduction
Kirovski Danijela
University of Belgrade
Website
RSwg31. Molecular aspects of endocrinology
2. Molecular aspects of endocrinology
3. Metabolomics
  • Animal models
  • Biochemical
  • Clinical
1. domestic animals
2. PCR technique
3. Loading tests
1. Domestic animals
2. cell signaling
3. metabolism
Daniel Legler
Biotechnology Institute Thurgau at the University of Konstanz
CHWG1, WG2, WG31. Mathematics
2. Mathematics
3. Mathematics
  • Computational
  • Computational
  • Computational

1. GPCR signaling
2. Chemokine
3. Cell migration
Ler Daria
Eurofarm Centar Polyclinic
Website
falsewg1, wg2, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Proteomics
  • Clinical
  • Biochemical
  • Cell biology
1. molecular biomarkers
2. cancer biology
3.
KELES Didem
Izmir University of Economics
TRwg2, wg3 1. Fundamental mechanisms underlying cancer
2. Fundamental mechanisms underlying cancer
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Biochemical
  • Cell biology
1. Zymography
2. Western blotting
3. 3D spheroid
1. Cancer metastasis and extracellular matrix
2. Drug repurposing
3. Voltage gated sodium channels and signaling
Djordjevic Ana
Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade
Website
RSwg2, wg31. Molecular aspects of endocrinology
2. Molecular aspects of endocrinology
3. Molecular mechanisms of signalling pathways
  • Animal models
  • Biochemical
  • Cell biology
1.
2.
3.
DOGAN SONER
Yeditepe University, School of Medicine
Website
TRwg21. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Epigenetics and gene regulation
  • Animal models
  • Cell biology
  • Biochemical
1. cancer mouse model
2. micro RNA array by afymetrix
3. Pyrosquencing
1. Epigenetics
2. Ageing
3. Calorie restriction
Vojnović Milutinović Danijela
Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade
Website
RSwg2, wg31. Molecular aspects of endocrinology
2. Molecular aspects of endocrinology
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Animal models
  • Cell biology
1. protein expression
2. metabolic disorders
3. histological analysis
1. PCOS
2. glucocorticoids
3. insulin signaling pathway
Vavers Edijs
Latvian Institute of Organic Synthesis
Website
LVwg31. Neurological disorders
2. Neurological disorders
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Animal models
  • Behavioral
1. Drug discovery, Molecular mechanisms, Screening
2. Stroke, Traumatic brain injury, Dementia, Epilepsy
3. Animal behaviour, Learning and memory, Depression, Anxiety, Pain perception, Neurological severity assessment
1. Sigma-1 chaperone protein
2. Epileptogenesis
3. Novel compounds
Feeney Emma
University College Dublin
IEwg21. Sensation and perception
2. Sensation and perception
3. Epidemiology and public health
  • Behavioral
  • Structural
  • Clinical
1. Sensory evaluation
2. taste perception
3. psychophysics
1. taste perception
2. sensory evaluation
3. food structure
Lacivita Enza
University of Bary
ITwg31. Medicinal chemistry
2. Medicinal chemistry
3. Neuronal development, plasticity and regeneration
  • Chemistry
  • Pharmacology
  • Computational
1. GPCRs
2. neuroinflammation
3. biased agonism
Ghosh Eshan
Copenhagen University
Website
DKwg1, wg3, wg4, wg5 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Fundamental aspects of synthetic biology and chemical biology
  • Biochemical
  • Cell biology
  • Structural
1. Protein chemistry
2. Co-immunoprecipitation
3. Cryo-EM and Crystallography
1. GPCR Structural Biology
2. Macromolecular Assembly
3. Protein Evolution
Moreno Estefanía
University of Barcelona
Website
ESwg1, wg21. Biochemistry
2. Biochemistry
3. Neural cell function, communication and signalling, neurotransmission
  • Biochemical
  • Biochemical
  • Pharmacology
1. Biophysical and immunological techniques
2. Functional techniques
3. Pharmacological techniques
1. The biochemistry, physiology and pharmacology of G-protein coupled receptors
2. Heteromerization of G Protein Coupled Receptors
3. Neurodegenerative and neurological diseases
Tripp Emma
University of Birmingham
Website
GBwg1, wg2, wg3, wg4, wg51. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Metabolism, biological basis of metabolism-related disorders
  • Pharmacology
  • Cell biology
  • Computational
1. Microscopy
2. BRET
1. GPCRs
2. Cell signalling
3. Adipocytes
Finn Olav Levy
University of Oslo
Website
NOWG1, WG21. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Fundamental mechanisms underlying cardiovascular diseases
  • Pharmacology
  • Animal models
  • Biophysical

1. PDE assays
2. HFpEF
3. FRET
1. Serotonin receptors
2. Cyclic nucleotides
3. Phosphodiesterases
Fierro Fabrizio
Hebrew University
ILwg1, wg31. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Systems neuroscience and computational neuroscience
  • Computational
  • Structural
  • Biochemical
1. Homology modelling
2. Docking
3. Molecular Dynamics
1. GPCR
2. bitter taste receptors
3.
Ballante Flavio
Uppsala University
Website
SEwg3, wg4, wg5 1. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Computational
  • Computational
1. Structure-based drug design
2. Ligand-based drug design
3. Quantitative modelling
1. Drug design
2. Computational chemistry
3. Medicinal chemistry
Wilhelm Florian
ETH Zürich
CHwg1, wg2, wg41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Physics of biological systems
  • Biophysical
  • Pharmacology
  • Pharmacology
1. Atomic Force Microscopy
2. Ligand Binding
3. cellular FRET-based kinetic assays
1. Arrestin
2. GPCR Phosphorylation
3. GPCR Signaling
Mayor Jr Federico
Universidad Autónoma Madrid
ESwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Cell biology
  • Animal models
  • Biochemical
1.
2.
3.
Acher Francine
University Paris Descartes
Website
FRwg31. Medicinal chemistry
2. Medicinal chemistry
3. Neurological disorders
  • Chemistry
  • Pharmacology
  • Structural
1. medicinal chemistry
2. neuropharmacology
3. molecular modeling
1. glutamate
2. GPCRs
3. transporters
van Westen Gerard
Leiden University (LACDR)
Website
NLwg3, wg4 1. Artificial intelligence, intelligent systems, multi agent systems
2. Artificial intelligence, intelligent systems, multi agent systems
3. Medicinal chemistry
  • Computational
  • Computational
  • Computational
1. machine-learning
2. structure-based
3. proteochemometrics
1. neural-networks
2. GPCRs
3. oncology
Wolber Gerhard
Freie Universitaet Berlin
DEwg3, wg4, wg51. Medicinal chemistry
2. Machine learning
3.
  • Computational
  • Chemistry
  • Structural
1. virtual screening
2. dynophores
3. functional selectivity
Morra Giulia
Consiglio Nazionale delle Ricerche
ITwg1, wg3 1. Biocomputing and molecular computation
2. Biocomputing and molecular computation
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Computational
  • Computational
  • Computational
1. Modeling of allosteric phenomena
2. protein dynamics
3. Drug discovery
Innamorati Giulio
University of Verona
ITwg1, wg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Biochemical
  • Pharmacology
Mangiatordi Giuseppe Felice
National Research Council
ITwg1, wg2, wg3, wg4, wg51. Computational biology
2. Computational biology
3. Theoretical and computational chemistry
  • Computational
  • Biophysical
  • Structural
1. Drug Design, Structure Prediction
2. QM/MM, ADMET
3. Molecular Dynamic Simulation
1. Docking simulations
2. MD simulations
3. Cannabinoid receptors
Tatar Gizem
Karadeniz Technical University
TRwg21. Bioinformatics
2. Bioinformatics
3. Computational biology
  • Computational
  • Chemistry
  • Biophysical
1. Computational Drug Design
2. Computational Biology and Bioinformatics
3. Molecular Biology and Genetics
Krause Gerd
Leibniz-Forschungsinstitut für molekulare Pharmakologie (FMP)
Website
DEwg3, wg5 1. Molecular architecture and structure
2. Molecular architecture and structure
3. Molecular aspects of endocrinology
  • Pharmacology
  • Structural
  • Computational
1. molecular
2. bioinformatics
3. protein design
1. membrane proteins
2. structure-function relationshipss
3. pharmacological intervention
Ladds Graham
Cambridge
GBwg1, wg2, wg3, wg41. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Computational
  • Biochemical
1. GPCRs
2. Modelling
3. Pharmacology
Guccione Salvatore
Catania
Website
ITwg31. Medicinal chemistry
2. Medicinal chemistry
3. Organic chemistry
  • Computational
  • Computational
  • Computational
1. Drug Design
2. Drug synthesis
3.
Lebon Guillaume
Montpellier Universsity
FRwg1, wg2, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Macromolecular complexes
  • Biochemical
  • Structural
  • Pharmacology
1. Membrane protein
2. X-ray, cryoEM
3. GPCRs
1. GPCRs signal transduction
2. Structural Biology
3. pharmacology
Çubukçuoğlu Deniz Günseli
Ankara University
TRwg1, wg21. Stem cell biology
2. Stem cell biology
3. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology
  • Cell biology
  • Biophysical
  • Computational
1. cell culture
2. pcr, wb
3. microarray
1. heart failure
2. heart rhythm
3. molecular signaling of cardiomyocytes
Dr. Henry Vischer
Vrije Universiteit Amsterdam
NLWG1, WG3, WG3, WG41. Cell signalling and signal transduction
2. Biological chemistry
3. Medicinal chemistry
  • Cell biology
  • Pharmacology
  • Computational

Bräuner-Osborne Hans
University of Copenhagen
Website
DKwg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Computational
  • Computational
1. GPCR
2. molecular pharmacology
3. mechanism-of-action
Cabadak Hulya
Marmara University School of Medicine
TRwg2, wg31. Molecular mechanisms of signalling pathways
2. Cell cycle, division and growth
3. Cell death (including senescence) and autophagy
  • Cell biology
  • Pharmacology
  • Biochemical
1. Cell culture and western blotting
2. Signalling pathway detection with ELİSA (NO,cAMP,Ca etc.)
3. Nücleic acid isolation (DNA,RNA) ,Real time PCR,
1. GPCR and G proteins, Cell growth and Death Pathway
2. Drug effects on GPCR and related signalling pathways
Biebermann Heike
Charité Universitätsmedizin Berlin
Website
DEwg2, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Biochemical
1. signalling modulation
2. biased signaling
3. pathway selected ligands
Danielson Helena
Uppsala University
SEwg1, wg3, wg41. Biochemistry
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biochemical
  • Biophysical
  • Structural
1. Molecular interactions
2. Molecular interactions
1. Molecular interactions
2. Drug discovery
3. Method development
CASTEL Hélène
University Rouen Normandie
Website
FRwg1, wg2, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Neural cell function, communication and signalling, neurotransmission
  • Cell biology
  • Animal models
  • Behavioral
1. Invasion
2. Transparization iDISCO
3. cell behavior
1. Neuro-oncology
2. animal behavior
3. Cancer
Daver Henrik
University of Copenhagen
DKwg1, wg3 1. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational
1. MD simulations
2. DFT calculations
1. Protein-protein interactions
2. Computational drug design
Gutierrez de Teran Hugo
Uppsala University
Website
SEwg3, wg4, wg5 1. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Biocomputing and molecular computation
  • Computational
  • Structural
  • Chemistry
1. Molecular Dynamics
2. Structural Bioinformatics
3. Free Energy Calculations
1. GPCR
2. Free Energy
3. adenosine receptors
Erol Ismail
Gebze Technical University
TRwg1, wg4, wg5 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Biocomputing and molecular computation
  • Computational
  • Structural
  • Biophysical
1. GPCRs
2. Molecular simulations
3. oligomerization
Iatrou Kostas
National Centre for Scientific Research "Demokritos"
Website
GRwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Sensation and perception
  • Biochemical
  • Pharmacology
  • Behavioral
1. cell-based screening systems
2. ligand binding assays
3. insect attraction-repellence assays
1. insects
2. odorant receptors
3. olfactory function modulators
Simon Icaro Ariel
University of Copenhagen
DKwg1, wg2, wg3, wg4, wg51. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Biocomputing and molecular computation
  • Computational
  • Chemistry
  • Structural
1. Molecular dynamics
2. Structure-activity relationships
3. Homology modeling
1. molecular modeling
2. gpcr
3. biased signalling
IJzerman Ad
Leiden University
falsewg31. Medicinal chemistry
2. Medicinal chemistry
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Chemistry
  • Computational
1. GPCR, adenosine receptors
2. new chemical entities, chemical probes
3. homology modeling, (Q)SAR
1. target binding kinetics
2. allosteric modulation
3. GPCR structure
Sylte Ingebrigt
UiT The Arctic University of Norway
NOwg1, wg31. Theoretical and computational chemistry
2. Molecular architecture and structure
3. Medicinal chemistry
  • Computational
  • Pharmacology
  • Chemistry
1. Virtual ligand screening
2. Molecular dynamics simulations
3. Homology modeling and in silico mutations
1. G-protein coupled receptors
2. Transporter proteins
3. Molecular mechanisms
Moreira Irina
Coimbra University
Website
PTwg1, wg4, wg5 1. Computational biology
2. Computational biology
3. Machine learning
  • Computational
  • Chemistry
  • Structural
1. Deep-learning
2. Drug discovery
3. GPCR function-structure
Georgoussi Zafiroula-Iro
National Centre for Sceintific Research "Demokritos"
Website
GRwg1, wg2, wg3, wg4, wg51. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Neural cell function, communication and signalling, neurotransmission
  • Cell biology
  • Pharmacology
  • Biochemical
1. GPCR function
2. Bias signaling
3. GPCR pharmacology
1. Opioid receptors
2. G and RGS proteins and effectors
3. G protein signaling-dependent behaviors
Hanson Julien
University of Liège
Website
BEwg1, wg2, wg3, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Pharmacology
  • Cell biology
1. orphan GPCR
2. Endocrinology
3. Metabolism
Grimes Jak
University of Birmingham
GBwg1, wg2, wg41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Physics of biological systems
  • Biophysical
  • Pharmacology
  • Cell biology
1. Single-Molecule Microscopy
2. GPCR
3. Cell-based assays
1. single-particle tracking of GPCRs
2. Receptor Pharmacology
3. Computational analysis of receptor dynamics
golebiowski jerome
U cote d azur
Website
FRwg31. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Pharmacology
1. smell
2. taste
García Nafría Javier
Institute of Biocomputation and Physics of Complex Systems, University of Zaragoza
ESwg11. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Macromolecular complexes
  • Structural
  • Biophysical
  • Biochemical
1. membrane protein complexes
2. structural biology
3. cryo-EM
Mathiesen Jesper
Zealand Pharma
DKwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Cell signalling and signal transduction
  • Pharmacology
  • Biochemical
  • Structural
Tiemann Johanna
University Leipzig
DEwg1, wg2, wg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Computer graphics, computer vision, multi media
  • Computational
  • Structural
  • Pharmacology
1. MD
2. Modeling
3. Design
1. GPCR dynamics
2. Dynamic network
3. Knowledge collection
Blanco Canosa Juan Bautista
Institute for Advanced Chemistry of Catalonia
Website
ESwg3, wg41. Biological chemistry
2. Biological chemistry
3. Organic chemistry
  • Chemistry
  • Chemistry
  • Biophysical
1. Sonic Hedgehog
2. protein synthesis
3. posttranslation modifications
Villà-Freixa Jordi
Universitat Internacional de Catalunya
ESwg1, wg31. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions
2. Theoretical and computational chemistry
3. Fundamental aspects of synthetic biology and chemical biology
  • Computational
  • Chemistry
  • Structural
1. Molecular Dynamics
2. Enzymes
3. Modelling
1. Enzyme catalysis
2. Molecular modelling
3. Protein interactions
Voß Jan Hendrik
University of Bonn
DEwg1, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3.
  • Pharmacology
  • Biochemical
  • Computational
1. Radioligand-binding experiments
2. Site-directed mutagenesis
3. Molecular dynamics
1. Binding kinetics
2. Structure-function relationship
3.
Springael Jean-Yves
Université Libre de Bruxelles
Website
BEwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. 9. Immunity and Infection
  • Pharmacology
  • Biochemical
  • Biophysical
1. Binding (Caturation/Competition/Association-Dissociation kinetics)
2. Signaling (G prot/Arrestin/cAMP/Ca/MAPK/Endocytosis/Chemotaxis)
3. BRET
1. GPCR
2. chemokine
3. BRET
Harpsøe Kasper
University of Copenhagen
Website
DKwg3, wg5 1. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Bioinformatics
  • Computational
  • Computational
  • Computational
1. Ligand binding mode prediction
2. Molecular dynamics simulation
3. In silico prediction of protein mutagenesis
1. Biased agonists
2. Inhibitors of G protein mediated signaling
3. Analysis of ligand binding determinants
Nemec Katarina
Max Delbrück Center for Molecular Medicine
Website
DEwg1, wg2, wg3, wg4, wg51. Biological chemistry
2. Biological chemistry
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Cell biology
  • Biochemical
1. GPCR
2. RAMP
3. HTS
Tate, Chris
MRC Laboratory of Molecular Biology
Website
GBWG1, WG41. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Macromolecular complexes
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Structural
  • Biophysical
  • Biochemical

1. cryo-EM & X-ray crystallography
2. ITC & SPR
3. Expression & purification
1. GPCR complexes
2. Structure
3. Dynamics
Vachkova Ekaterina
Trakia University
Website
BGwg1, wg2 1. Stem cell biology
2. Stem cell biology
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Animal models
  • Biochemical
1. isolation stem cells
2. aplication of stem cells and their products
3. nutritional factors
1. stem cells
2. adipose tissue
3. regenerative medicine
Jonas Kim
King’s College London
GBwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Molecular aspects of endocrinology
  • Cell biology
  • Pharmacology
  • Biochemical
1. Single molecule imaging
2. GPCR
3. GPCR
1. GPCRs
2. Endocrinology
3. Cellular signalling
Krasel, Cornelius
Philipps-University Marburg
Website
DEWG11. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Mathematics (applications in science and industry)
  • Pharmacology
  • Biochemical
  • Cell biology

Nativi, Cristina
University of Florence
Website
ITWG31. Organic chemistry
2. Glycomics/Lipidomics
3. Glycobiology
  • Chemistry
  • Computational
  • Computational

1. In vitro tests
2. Animal model
3. Glycobiology
Sotelo, Eddy
University of Santiago de Compostela
Website
ESWG2, WG3, WG41. Medicinal chemistry
2. Biological chemistry
3. Fundamental aspects of synthetic biology and chemical biology
  • Chemistry
  • Chemistry
  • Pharmacology

1. Synthesis ligands
2. conjugation strategies
3. GPCRs
1. Optimization of new ligands
2. New conjugation strategies
3. Biasedligands, allosteric modulators and bitopic ligands
Osborne, Greg
Heptares Therapeutics
Website
GBWG1, WG2, WG3, WG41. Mathematics (applications in science and industry)
2. Mathematics (applications in science and industry)
3. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational

Alves Isabel
U. of Bordeaux
FRwg1, wg3, wg41. Molecular mechanisms of signalling pathways
2. Spectroscopic and spectrometric techniques
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Biophysical
  • Biophysical
  • Biochemical
1. plasmon resonance
2. calorimetry
3. signal transduction cascades
1. lipid impact in signal transduction
2. membrane active peptides
3. receptor reconstitution in model membranes
Liebscher, Ines
Leipzig University
DEWG1, WG21. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Biochemical
  • Pharmacology
  • Animal models

1. Adhesion GPCR
2. Mechano-activation
3. Deorphanization
Dr. Julie Sanchez
University of Nottingham
UKWG1, WG2, WG31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics
  • Pharmacology
  • Cell biology
  • Pharmacology

1. BRET - FRET
2. Fluorescent biosensors
3. Ligand characterisation
1. GPCR signalling and modulation
2. GPCRs involved in CNS disorders and pain
3. Chemokine receptors
Nikolic Katarina
University of Belgrade, Faculty of Pharmacy
Website
RSwg3, wg51. Medicinal chemistry
2. Medicinal chemistry
3. Systems neuroscience and computational neuroscience
  • Computational
  • Chemistry
  • Biochemical
1. Computer-Aided Drug Design
2. Molecular Dynamic Simulations
3. Virtual Screening
1. serotonin receptors antagonists
2. alpha2/imidazoline receptor agonists
3. kinase inhibitors
Kosloff Mickey
University of Haifa
Website
ILwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Computational
  • Biochemical
  • Structural
1. Structural bioinformatics

1. G proteins, GAPs, effectors
2. Interaction specificity
3. Signaling complexes
Kostenis Evi
University of Bonn
DEwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Biochemical
1. signal transduction
2. signal transduction
3. signal transduction
1. GPCR
2. G Protein
3. signal transduction
Khakurel Krishna
Institute of Physics
CZwg3, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Scientific computing, simulation and modelling tools
  • Structural
  • Computational
  • Biophysical
1. MicroED, CryoEM
2. Data Analysis, Computational tools Development
3. Spectroscopy and microscopy
1.
2.
3.
Chung Ka Young
Sungkyunkwan University
falsewg11. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Cell signalling and signal transduction
  • Structural
  • Biochemical
  • Cell biology
1. GPCR signaling
2. Protein conformation
Laasfeld Tõnis
University of Tartu
Website
EEwg4, wg5 1. Method development in chemistry
2. Method development in chemistry
3. Systems biology
  • Pharmacology
  • Pharmacology
  • Computational
1. GPCR
2. Ligand binding models
3. Bioimage analysis
1. deep learning for bioimage analysis
2. superresolution microscopy
3. kinetic models of ligand binding
Lamghari Meriem
Institute Of Biomedical Engineering/Institute for Research and Innovation in Health Sciences
Website
PTwg21. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 7. Physiology, Pathophysiology and Endocrinology
  • Cell biology
  • Animal models
  • Cell biology
1. Microfluidic for cells communication studies
2. 3D cell culture models
3. Bioengineering
Barki-Harrington Liza
University of Haifa
ILwg1, wg2, wg3 1. Protein synthesis, modification, turnover
2. Protein synthesis, modification, turnover
3. Biochemistry
  • Biochemical
  • Cell biology
  • Pharmacology
1. GPCR
2. cyclooxygenase
3. protease
Stoddart Leigh
University of Nottingham
GBwg3, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Biophysical
  • Pharmacology
1. Resonance Energy Transfer (BRET, FRET)
2. Fluorescence correlation spectroscopy
3. Binding kinetics
1. Binding kinetics
2. Membrane organisation of receptors
3. GPCR fluorescent ligands
pardo leonardo
universidad autonoma de barcelona
Website
ESwg3, wg4 1. Computational biology
2. Computational biology
3. Bioinformatics
  • Computational
  • Computational
  • Computational
1. molecular dynamics
2. virtual screening
1. oligomerization
2. drug design
Nygaard Mads Mørup
University of Copenhagen
DKwg31. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Biochemistry
  • Structural
  • Computational
  • Computational
1. Peptides
2. Simulations
Leopoldo Marcello
Università degli Studi di Bari Aldo Moro
ITwg3, wg4 1. Medicinal chemistry
2. Medicinal chemistry
3. Fundamental aspects of synthetic biology and chemical biology
  • Chemistry
  • Pharmacology
  • Animal models
1. Allosteric modulators
2. Orphan Receptors
3. Biased agonists
Tahk Maris-Johanna
University of Tartu
Website
EEwg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Biochemistry
  • Biochemical
  • Biochemical
  • Biochemical
1. Genetically encoded FRET-based biosensors assays for cAMP and apoptosis
2. Fluorescence anisotropy
3. Making and using baculoviruses and BacMam systems
1. Cell signaling pathways
2. Ligand-receptor interactions
3. Biosensors
martinez Karen
University of Copenhagen
DKwg1, wg2, wg3, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Surface science and nanostructures
  • Biophysical
  • Computational
  • Computational
1. fluorescence microscopy

Floor Martin
University of Vic
Website
ESwg1, wg3, wg4 1. Biocomputing and molecular computation
2. Biocomputing and molecular computation
3. Fundamental aspects of synthetic biology and chemical biology
  • Biochemical
  • Biophysical
  • Computational
1. Protein design
2. Enzyme design
3. Structural bioinformatics
Szpakowska Martyna
Luxembourg Institute of Health
LUwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Cell biology
  • Pharmacology
  • Structural
1. GPCR
2. Chemokines
Niv Masha
The Hebrew University of Jerusalem, Israel
Website
ILwg3, wg5 1. Biochemistry
2. Biochemistry
3. Food sciences
  • Computational
  • Behavioral
  • Chemistry
1. homology modeling
2. sensory studies
3. chemoinformatics
1. GPCRs
2. taste receptors
3. drug discovery
Vrecl Fazarinc Milka
University of Ljubljana, Veterinary Faculty
Website
SIwg11. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Morphology and functional imaging of cells and tissues
  • Cell biology
  • Biophysical
  • Cell biology
1. confocal microscopy
2. BRET
3. fluorometric measurements
1. GPCRs
2. protein-protein interactions
3. ntracellular signaling
STOEBER MIRIAM
University of Geneva
Website
CHwg1, wg2, wg3, wg4, wg5 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Neural cell function, communication and signalling, neurotransmission
  • Cell biology
  • Biochemical
  • Pharmacology
1. Microscopy1. Subcellular Location
2. Signal Transduction
3. Neuropharmacology
Misicka-Kesik Alekssandra
University of Warsaw
PLwg11. Medicinal chemistry
2. Medicinal chemistry
3. Analytical chemistry
  • Chemistry
  • Pharmacology
  • Computational
1. HPLC MS
2. pain study
1. bifuncional peptidomimetics
2. MOR, DOR
3. melanocortin MC4 receptors
Wozniak Monika
University in Liege
BEwg2, wg3, wg4 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. 6. Cellular and Developmental Biology
  • Pharmacology
  • Biochemical
  • Cell biology
Grigorova Natalia
Trakia University
Website
BGwg1, wg21. Metabolism, biological basis of metabolism-related disorders
2. Metabolism, biological basis of metabolism-related disorders
3. Food sciences
  • Animal models
  • Cell biology
  • Biochemical
1. obesity-related disorders
2. bioactive food additives
3. signal transduction
Vardjan Nina
University of Ljubljana, Faculty of Medicine
SIwg21. 8. Neuroscience and Neural Disorders
2. 8. Neuroscience and Neural Disorders
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Cell biology
  • Biochemical
  • Animal models
1. Fluorescence Microscopy, Live cell imaging, IHC, ICC
2. WB, Biochemical assays
3. Drosophila, Rodents (mouse, rat) - animal models of neurological disorders
1. Astroglia physiology
2. GPCR-mediated cell signalling, metabolism, exocytosis
3. Neuorodegeneration
Saraiva Nuno
Universidade Lusófona
Website
PTwg1, wg2, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Cytoskeleton and cell behaviour
  • Cell biology
  • Cell biology
  • Cell biology
1. ROS and Ca2+ signalling
2. Cell motility
3. Cancer progression
Velickovic Natasa
Institute for biological research Sinisa Stankovic
Website
RSwg2, wg31. Metabolism, biological basis of metabolism-related disorders
2. Metabolism, biological basis of metabolism-related disorders
3. Non-communicable diseases
  • Biochemical
  • Animal models
  • Biochemical
1. protein expression
2. animal model of metabolic disease
3. hormone analysis
1. diabetes
2. hepatic metabolism
3. endocrinology
Sensoy Ozge
Istanbul Medipol University
TRwg1, wg2, wg3 1. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Cell signalling and signal transduction
  • Computational
  • Biophysical
  • Structural
1. Molecular dynamis simulation
2. Computational biophysics
3. Computational structural biology
1. GPCR biased signaling
2. Neurological disorders
3. Cancer
Pascale Crépieux
CNRS
Website
FRwg1, wg21. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Molecular aspects of endocrinology
  • Cell biology
  • Pharmacology
  • Computational
1. GPCR
2. VHH
3. Signaling Network
1. GPCR
2. signaling networks
3. mRNA translation
Scheerer Patrick
Charité - Universitätsmedizin Berlin
Website
DEwg1, wg2, wg3, wg4, wg51. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Structural
  • Biophysical
  • Biochemical
1. Protein X-ray Crystallography
2. Time-resolved Methods
3. Signal Transduction
1. Structural biology and Dynamics on GPCRs
2. Activation mechanisms of GPCRs
3. GPCR Signal Transduction
Jockers Ralf
University of Paris
Website
FRwg2, wg3 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Cell signalling and signal transduction
  • Biochemical
  • Pharmacology
  • Animal models
1. GPCR
2. Melatonin
3. Leptin
Reiner-Link David
University of Copenhagen
DKwg1, wg2, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular mechanisms of signalling pathways
3. Biological chemistry
  • Pharmacology
  • Biochemical
  • Chemistry
1. Analytical GPCR Pharmacology
2. Biochemistry of Proteins
3. Spectroscopic Analytics
1. Ligand-Receptor Binding Kinetics
2. Biased Signalling
3. Allosterism and GPCR Oligomerization
Lane Rob
University of Nottingham
Website
GBwg1, wg2, wg3, wg4 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Fundamental aspects of synthetic biology and chemical biology
  • Pharmacology
  • Cell biology
  • Structural
Zorec Robert
Univerza v Ljubljani, Medicinska fakulteta
SIwg21. Organelle biology and trafficking
2. Organelle biology and trafficking
3. 7. Physiology, Pathophysiology and Endocrinology
  • Cell biology
  • Biophysical
  • Pharmacology
1. electrophysiology
2. super-resolution microscopy
1. membrane fusion
2. astrocytes and neurodegeneration
3. cancer cell vaccine
Yvinec Romain
INRA
Website
FRwg1, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
1.
2.
3.
Rosenkilde Mette
UCPH
Website
DKwg1, wg2, wg3 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Biological chemistry
  • Pharmacology
  • Biochemical
  • Clinical
1. Signal transduction, biased signaling
2. kinetics and dynamics of receptor-ligand interactions
3. translational sciences
Castro Rui
Faculty of Pharmacy, University of Lisbon
Website
PTwg21. Metabolism, biological basis of metabolism-related disorders
2. Metabolism, biological basis of metabolism-related disorders
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Cell biology
  • Animal models
1. Liver Disease
2. microRNAs
3. biomarkers & therapies
Sencanski Milan
Vinča Institute of Nuclear Sciences
Website
RSwg31. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational
1. GPCRs
2. Chronic and infectious diseases
3. Drug repurposing
Filipek Slawomir
University of Warsaw
Website
PLwg1, wg2, wg3, wg4, wg51. Biocomputing and molecular computation
2. Biocomputing and molecular computation
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational
1. molecular modeling and dynamics
2. drug design
3. web-based tools
1. GPCRs
2. signaling and biased signaling
3. ligand gated ion channels
Mistry Shailesh
University of Nottingham
Website
GBwg31. Medicinal chemistry
2. Medicinal chemistry
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Chemistry
  • Chemistry
  • Chemistry
1. Peptide and small molecule synthesis
2. Drug discovery
3. Chemical tool development (e.g. fluorescent ligands)
1. GPCRs
2. Allosteric and orthosteric ligands
3. Fluorescent probes
Prömel Simone
Universität Leipzig
DEwg1, wg21. Biochemistry
2. Cell signalling and signal transduction
3. Developmental genetics in animals and plants
  • Cell biology
  • Biochemical
  • Animal models
1. Adhesion GPCRs
2. Signalling
3. Physiological functions
Hansen Trond Vidar
University of Oslo
Website
NOwg31. 2. Physics and Chemistry
2. 2. Physics and Chemistry
3. Biological chemistry
  • Chemistry
  • Structural
  • Biochemical
1. Organic chemistry
2. Lipids
3. GPCRs
1. Medicinal chemistry
2. Agonists
3. Resolution of inflammation
Kukaj Taulant
Friedrisch Schiller University Jena
DEwg11. Molecular architecture and structure
2. Molecular architecture and structure
3. Medicinal chemistry
  • Biophysical
  • Cell biology
  • Pharmacology
Møller Thor
University of Copenhagen
DKwg1, wg3, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Pharmacology
  • Pharmacology
  • Biophysical
1. Second messenger signaling assays
2. Receptor trafficking
3. Fluorescence microscopy
1. Receptor trafficking
2. Intracellular signaling
3. Biosensors
Waldhoer Maria
InterAx Biotech
Website
CHwg2, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Computational biology
  • Pharmacology
  • Cell biology
  • Computational
FOGEL Wieslawa Agnieszka
Medical University of Lodz
Website
PLwg21. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Animal models
  • Pharmacology
  • Biochemical
1. animal models
2. Biochemical Pharmacology
3. behavioral
1. CNS disorders
2. animal models
3. GPCRs ligands
leroy xavier
Domain Therapeutics
FRwg1, wg2, wg3, wg4, wg51. Innate immunity
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Immunological mechanisms in disease
  • Pharmacology
  • Biochemical
  • Animal models
1. BRET; Spatiotemparal; GPCRs
2. Inflammasome
3. Immuno oncology
1. Immuno-oncology
2. GPCRs
3. Antibodies
Stefanachi, Angela
Università degli studi di Bari Aldo Moro
Website
ITWG3, WG41. Medicinal chemistry
2. Organic chemistry
3. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions
  • Chemistry
  • Cell biology
  • Computational

1. parallel synthesis
2. GPCR
3. Crystal structures
1. CB2
2. Cancer
3. Neurodegeneration
Paparde, Artūrs
Rīga Stradiņš university
Website
LVWG21. Fundamental mechanisms underlying cardiovascular diseases
2. Comparative physiology and pathophysiology
3. Organ physiology and pathophysiology
  • Computational
  • Computational
  • Computational

1. Atherosclerosis
2. Cardiovascular adaptation
3. (Patho-) physiology of atherosclerosis
Plouffe, Bianca
Queen's University Belfast
Website
GBWG2, WG31. Cell signalling and signal transduction
2. Fundamental mechanisms underlying cancer
3. Fundamental mechanisms underlying cardiovascular diseases
  • Pharmacology
  • Cell biology
  • Cell biology

1. GPCRs
2. compartmentalised G protein signalling
3. compartmentalised G protein signalling
1. Compartmentalised G protein signalling
2. GPCR signalling
Tautermann, Christofer
Boehringer Ingelheim Pharma GmbH & Co KG
DEWG2, WG31. Theoretical and computational chemistry
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Computational

1. Homology Modeling
2. MD simulations
3. Quantum Chemistry
1. Drug design
2. Computational chemistry
3. GPCR models
Gloriam, David
University of Copenhagen
DKWG3, WG51. Web and information systems, database systems
2. Theoretical and computational chemistry
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Computational
  • Structural
  • Pharmacology

1. open access databases
2. structure determination
3. ligand identification and optimisation
1. Open access databases
2. Computational drug design
3. Structure determination
Carlsson, Jens
Uppsala University
Website
SEWG3, WG4, WG51. Bioinformatics
2. Medicinal chemistry
3. Theoretical and computational chemistry
  • Computational
  • Computational
  • Computational

1. Virtual screening (Molecular docking)
2. Molecular dynamics simulations
3. Homology modeling
1. Polypharmacology/Selective/Biased ligands
2. Structural basis of GPCR activation
3. Accurate structural models of ALL GPCRs
Bennett, Kirstie
Sosei Heptares
Website
GBWG31. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Cellular and Developmental Biology
3. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Computational

1. GPCR
2. Molecular Pharmacology
Wessel Andressen, Kjetil
University of Oslo
Website
NOWG11. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Biophysical
  • Biophysical
  • Pharmacology

1. FRET
2. biosensor cGMP
3. biosensors
1. cGMP
2. 5-HT7 receptor
3. Cardiomyocyte
Lazar, Josef
Institute of Organic Chemistry and Biochemistry CAS
Website
CZWG1, WG2, WG3, WG41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Cell signalling and signal transduction
3. Spectroscopic and spectrometric techniques
  • Biophysical
  • Cell biology
  • Structural

1. polarization microscopy
2. G protein signaling
1. Cell signaling
2. Advanced optical microscopy
3. G proteins
Canals, Meritxell
University of Nottingham
GBWG1, WG2, WG3, WG41. Molecular mechanisms of signalling pathways
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Pharmacology
  • Cell biology
  • Biochemical

1. Opioid receptors
2. GPCRs
3. Signalling
Radi, Marco
University of Parma
Website
ITWG31. Medicinal chemistry
2. Method development in chemistry
3. Organic chemistry
  • Chemistry
  • Small molecules
  • Docking

1. small molecules
2. docking
3. combinatorial chemistry
1. CCR6
2. CXCR4
3. GPER-1
Contino, Marialessandra
University of Bari
ITWG3, WG41. Biological chemistry
2. Molecular mechanisms of signalling pathways
3. Neurological disorders
  • Pharmacology
  • Biochemical
  • Cell biology

1. GPCRs
2. GPCRs
3. GPCRs
1. GPCRs
2. Cancer
3. Neurodegeneration
Dubiel, Mariam
Heinrich Heine University of Duesseldorf
Website
DEWG11. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Neurological disorders
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Biochemical
  • Chemistry

Chabbert, Marie
CNRS
FRWG11. Computational biology
2. Molecular mechanisms of signalling pathways
3. Bioinformatics
  • Computational
  • Structural
  • Biophysical

1. GPCR
2. Biased Signaling
3. Molecular Simulations
Fardilha, Margarida
University of Aveiro
Website
PTWG2, WG31. Biochemistry
2. Genetics, ’Omics’, Bioinformatics and Systems Biology
3. Physiology, Pathophysiology and Endocrinology
  • Biochemical
  • Cell biology
  • Clinical

1. Male reproduction
2. Sperm motility
3. Protein phosphatase 1
Solano, Maria Marti
MRC Laboratory of Molecular Biology
GBWG1, WG31. Molecular mechanisms of signalling pathways
2. Computational biology
3. Systems biology
  • Computational
  • Structural
  • Pharmacology

1. Pharmacogenomics
2. Signalling bias
3. Structural Biology
Corminboeuf, Olivier
Idorsia Pharmaceuticals Ltd
Website
FRWG1, WG2, WG3, WG41. Medicinal chemistry
2. Immunological mechanisms in disease
3. Pharmacology and pharmacogenomics
  • Chemistry
  • Biochemical
  • Pharmacology

1. Medicinal Chemistry
2. Oncology
3. Immunology
D'Ursi, Pasqualina
National Research Council
Website
ITWG11. Molecular architecture and structure
2. Bioinformatics
3. Medicinal chemistry
  • Structural
  • Biochemical
  • Pharmacology

1. Protein
2. Function
3. drug design
1. Bionformatics
2. Protein structure activity
3. Drug design
Dr. Henri Xhaard
University of Helsinki
FIWG3, WG51. Molecular architecture and structure
2. Bioinformatics
3. Web and information systems, database systems
  • Computational
  • Structural
  • Biochemical

1. Databases for sequence/structure analysis
2. Protein and protein-ligand complexes modeling
3. Virtual ligand screening and design
1. Machine learning
2. Ligand design
3. Structural modeling
Kiec-Kononowicz Katarzyna
Jagiellonian University
PLwg31. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
1. medicinal chemistry
2. GPCRs
3. drug-like properties
Kozielewicz Pawel
Karolinska Institutet
SEwg2, wg3 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Biocomputing and molecular computation
  • Pharmacology
  • Cell biology
  • Computational
1. Receptors
2. signaling
3. molecular dynamics
1. GPCRs
2. small ligands
3. drug discovery
Frank Philippe
University of Tours
FRwg1, wg2, wg3, wg4, wg51. Fundamental mechanisms underlying cancer
2. Lipid biology
3. Fundamental mechanisms underlying cardiovascular diseases
  • Animal models
  • Cell biology
  • Biochemical
1. Breast cancer model
2. Lipid metabolism
3. Lipid quantitification
1. Breast Cancer
2. Cholesterol metabolism
3. Atherosclerosis
Leurs Rob
Vrije Universiteit
falsewg1, wg2, wg3, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Chemistry
  • Computational
1. histamine receptors
2. chemokine receptors
Schiedel Anke
University of Bonn
DEwg1, wg2 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Cell biology
  • Pharmacology
  • Computational
1. GPCR
2. signal transduction
3. protein protein interactions
Sposini Silvia
CNRS
FRwg1, wg2, wg3, wg4, wg5 1. Organelle biology and trafficking
2. Organelle biology and trafficking
3. Cell signalling and signal transduction
  • Biophysical
  • Pharmacology
  • Cell biology
1. TIRF microscopy
2. Receptor Signalling
3. Neuronal cultures
1. GPCR
2. Membrane Trafficking
3. Endosomal signalling
Bradley Sophie
University of Glasgow
GBwg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Behavioral
  • Animal models
Garcia-Sosa Alfonso T.
University of Tartu
Website
EEwg3, wg5 1. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Medicinal chemistry
  • Computational
  • Computational
  • Computational
1. drug design
2. drug discovery
3. molecular simulation
Tunaru Sorin
Institute of Biochemistry, Romanian Academy
ESwg2, wg3 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Lipid biology
  • Pharmacology
  • Cell biology
  • Biochemical
1. orphan GPCR, drug discovery, assay development
2. lipolysis, pancreatic beta cells, insulin signaling
3. ligand purification,
1. obesity
2. drug addiction
3. neurodegeneration
Uldrijan Stjepan
Masaryk University
Website
CZwg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Cell cycle, division and growth
  • Cell biology
  • Biochemical
  • Pharmacology
1. Cell signaling
2. ERK pathway
3. Melanoma
Murga, Cristina
Universidad Autónoma de Madrid
Website
ESWG2, WG31. Cell signalling and signal transduction
2. Metabolism, biological basis of metabolism-related disorders
3. Organ physiology and pathophysiology
  • Biochemical
  • Animal models
  • Cell biology

1. Western Blot
2. Glucose and Insulin tolerance tests
3. Immunofluorescence
1. Signalling
2. Pathophysiology
3. Metabolism
Kellenberger, Esther
Université de Strasbourg
Website
FRWG31. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Structural

1. virtual screening
2. docking
3. pharmacophore
1. Molecular recognition
2. Structure-activity relationship
3. G-protein coupled receptor
Nyagulova Kandemish, Emilia
Bahçeşehir University
Website
TRWG21. Molecular mechanisms of signalling pathways
2. Non-coding RNAs
3. Cell signalling and signal transduction
  • Cell biology
  • Cell biology
  • Cell biology

1. Cell culture
2. Gene expression
3. Protein expression
1. Cell signaling
2. Cancer
3. Non-coding RNAs
Žerovnik, Eva
Institute "Jožef Stefan"
SIWG1, WG3, WG4, 1. Physical chemistry of biological systems
2. Biological chemistry
3. Nanophysics
  • Biochemical
  • Biophysical
  • Cell biology

1. CD, NMR
2. AFM, TEM, STED
3. Western blots, proteomics
1. Protein folding
2. Protein aggregation
3. Cascade of neurodegeneration
Hamann, Jörg
Amsterdam University Medical Centers
NLWG21. Immunological mechanisms in disease
2. Regulation and effector functions of the immune response
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Animal models
  • Clinical

1. Expression profiling
2. Zebrafish
3. Multiple sclerosis
1. Adhesion GPCRs
2. Microglia
3. T cells
M Keseru, György
Research Center for Natural Sciences
Website
HUWG31. Medicinal chemistry
2. Fundamental aspects of synthetic biology and chemical biology
3. Theoretical and computational chemistry
  • Chemistry
  • Chemistry
  • Computational

1. Medicinal chemistry
2. Chemical biology
3. Drug design
Bermudez, Marcel
Freie Universität Berlin
Website
DEWG1, WG3, WG51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational

1. virtual screening
2. molecular dynamics
3. drug design
1. GPCR pharmacology
2. Rational drug design
3. Signal tranduction
Capiod, Thierry
Université Paris-Descartes
Website
FRWG2, WG31. Cellular and Developmental Biology
2. Physiology, Pathophysiology and Endocrinology
3. Immunity and Infection
  • Cell biology
  • Cell biology
  • Biophysical

1. Prostate
2. Cancer
3. Calcium
Sommer, Martha
Charité Medical University Berlin
Website
DEWG1, WG21. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Biochemistry
  • Biophysical
  • Biochemical
  • Biochemical

1. Arrestin activation mechanism
2. Arrestin-GPCR interactions
3. Biological roles of arrestin
Stark, Holger
Heinrich Heine University Düsseldorf
Website
DEWG1, WG2, WG31. Cell signalling and signal transduction
2. Glycomics/Lipidomics
3. Neural cell function, communication and signalling, neurotransmission
  • Chemistry
  • Pharmacology
  • Biochemical

1. Drug design
2. GPCR screening
3. enzyme screening
1. Medicinal Chemistry
2. Drug development
3. Neurotransmitter
Mordalski, Stefan
Intomics A/S
DKWG1, WG31. Molecular mechanisms of signalling pathways
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)

  • Computational
  • Computational
  • Computational

Horvat Anemari
University of Ljubljana, Faculty of Medicine
SIwg1, wg2, wg3, wg4, wg51. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Metabolism, biological basis of metabolism-related disorders
  • Cell biology
  • Animal models
  • Biochemical
1. Metabolism
2. cAMP and Ca2+ signaling
3. Neurodegeneration
Laurenzana Anna
University of Florence
ITwg21. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Cell junctions, cell adhesion, cell communication and the extracellular matrix
  • Cell biology
  • Biochemical
  • Clinical
1. cell membrane receptors
2. protein immunoprecipitation
3. Xenograft models of human cancer
1. cell biology
2. molecular biology
3. cancer
Markus Muttenthaler
University of Vienna
Website
ATWG2, WG3, WG4, WG51. Biological chemistry
2. Medicinal chemistry
3. Pharmacology and pharmacogenomics
  • Chemistry
  • Pharmacology
  • Biochemical

1. Peptides
2. GPCRs and Ion channels
1. Neuropeptides
2. Venoms to Drugs
3. Medicinal Chemistry
Thorsen Thor S.
University of Copenhagen
Website
DKwg1, wg2, wg31. Molecular architecture and structure
2. Molecular architecture and structure
3. Physical chemistry of biological systems
  • Structural
  • Pharmacology
  • Cell biology
1. electron microscopy
2. drug design
3. signaling
1. membrane proteins
2. drug design
3. structure determination
Namasivayam Vigneshwaran
University of Bonn
DEwg3, wg4, wg51. Artificial intelligence, intelligent systems, multi agent systems
2. Artificial intelligence, intelligent systems, multi agent systems
3. Theoretical and computational chemistry
  • Computational
  • Computational
  • Computational
Cong, Xiaojing
Université Côte d'Azur
FRWG1, WG2, WG31. Theoretical and computational chemistry
2. Physical chemistry of biological systems
3. Bioinformatics
  • Computational
  • Biophysical
  • Chemistry

Franziska Heydenreich
Stanford University
USWG1, WG21. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Computational biology
  • Pharmacology
  • Biophysical
  • Computational

1. cell signalling
2. fluorescence
3. data science
1. Signalling
2. Conformations
vischer henry
Vrije Universiteit Amsterdam
NLwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Biological chemistry
3. Medicinal chemistry
  • Cell biology
  • Pharmacology
  • Computational
Scarpa Miriam
University of Glasgow
GBwg2, wg31. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Neurological disorders
  • Biochemical
  • Pharmacology
  • Behavioral
Schöneberg Torsten
Leipzig University
DEwg2, wg31. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Evolutionary genetics
  • Biochemical
  • Animal models
  • Pharmacology
Łażewska Dorota
Jagiellonian University Medical College
PLwg2, wg31. Medicinal chemistry
2. Medicinal chemistry
3. Organic chemistry
  • Chemistry
  • Chemistry
  • Chemistry
1. synthesis of GPCR ligands
2. medicinal chemistry
1. GPCR ligands
2. CNS disorders
3. drug synthesis
Esguerra Neira Mauricio
University of Copenhagen
DKwg1, wg51. Web and information systems, database systems
2. Molecular mechanisms of signalling pathways
3. Computational biology
  • Computational
  • Chemistry
  • Structural
1. gpcr
2. knowledge based analysis
3. interaction networks and prediction
Chevillard Florent
Idorsia Pharmaceuticals Ltd
CHwg3, wg4, wg51. Theoretical and computational chemistry
2. Machine learning
3. Bioinformatics
  • Computational
  • Pharmacology
  • Biochemical
1. Fragment
2. GPCR
3. Modeling
Doğan Berna
Bahcesehir University
TRwg1, wg2, wg3, wg41. Physical chemistry
2. Theoretical and computational chemistry
3. Machine learning
  • Computational
  • Computational
  • Computational
Gentry Patrick
University of Copenhagen
DKwg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular mechanisms of signalling pathways
3. Medicinal chemistry
  • Pharmacology
  • Chemistry
  • Computational
1. GPCR
2. Medicinal Chemistry
1. GPCR
2. Orphan receptors
3. Allosteric modulators
O'Brien Shannon
University of Birmingham
GBwg1, wg21. Molecular mechanisms of signalling pathways
2. Metabolism, biological basis of metabolism-related disorders
3. Molecular aspects of endocrinology
  • Pharmacology
  • Cell biology
  • Computational
1. G protein-coupled receptors
2. cell signalling
3. protein-protein interactions
Gabrielsen Mari
UiT Arctic University of Norway
NOwg31. Theoretical and computational chemistry
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Psychiatric disorders
  • Computational
  • Pharmacology
  • Computational
1. GPCRs
2. Molecular modelling
3. Pharmacology
Russotto Clizia
UiT - Arctic University of Norway
NOwg1, wg2, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Scientific computing, simulation and modelling tools
3. Imaging for medical diagnosis
  • Computational
  • Computational
  • Computational
1. molecular modelling

1. P.E.T. radioactive tracers
2. GnR-Hr
3. Glioblastoma
Koszegi Zsombor
University of Birmingham
GBwg11. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Cell biology
  • Biochemical
  • Computational
1. single-molecule
2. microscopy
1. single-molecule
2. TIRF
3. GPCR
Middleton Daniel
University of Copenhagen
DKwg1, wg3, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Structural
  • Biochemical
  • Pharmacology
Lanoiselée Yann
University of Birmingham
GBwg1, wg2, wg3, wg41. 1. Mathematics (applications in science and industry)
2. Statistical physics
3. Physics of biological systems
  • Computational
  • Biophysical
  • Computational
1. diffusion
2. complex systems
3. inverse problems
Zarzycka Barbara
Vrije Universiteit Amsterdam
NLwg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Molecular architecture and structure
  • Computational
  • Structural
  • Biophysical
1. computer-aided drug design
2. molecular modulators
3. medicinal chemistry
Andric Silvana
Faculty of Sciences, University of Novi Sad
RSwg21. Cell signalling and signal transduction
2. Molecular aspects of endocrinology
3. Molecular mechanisms of signalling pathways
  • Animal models
  • Cell biology
  • Biochemical
Bećin Alisa
University of Novi Sad (UNS)
RSwg21. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Molecular aspects of endocrinology
  • Cell biology
  • Cell biology
  • Cell biology
1. Transcriptomic analysis
2. Photometric analysis
3. Immuno assays
1. Chronobiology
2. Stress
3. Leydig cells
Radovic Pletikosic Sava
University of Novi Sad
RSwg21. Molecular aspects of endocrinology
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Animal models
  • Cell biology
  • Biochemical
1. knockout mice
2. RNA/DNA/protein manipulation and analyses
3. enzyme immunoassays
1. mitochondrial dynamics
2. steroidogenesis
3. insulin and IGF1 receptors
Marinković Dijana
University of Novi Sad, Serbia
RSwg21. Cell signalling and signal transduction
2. Molecular aspects of endocrinology
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Cell biology
  • Biochemical
1. DNA/RNA/protein manipulation

1. Chronobiology
2. Leydig cells
Miljus Tamara
University of Birmingham
GBwg1, wg31. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Biochemistry
  • Biophysical
  • Structural
  • Pharmacology
1. GPCRs
2. biased signalling
3. molecular basis of GPCR signalling
Harwood Clare
University of Nottingham
GBwg11. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Pharmacology
  • Biochemical
  • Computational
1. molecular efficacy
2. single molecule pharmacology
Ambriović-Ristov Andreja
Ruđer Bošković Institute
HRwg1, wg21. Cell junctions, cell adhesion, cell communication and the extracellular matrix
2. Cytoskeleton and cell behaviour
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Cell biology
  • Biophysical
1. adhesome analysis using proteomics
2. in vitro cell migration and invasion
3. immunofluorescence
1. integrin adhesion complexes
2. cancer
3. crosstalk between GPCRs and integrins
Hanson Julien
University of Liège
BEwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Organ physiology and pathophysiology
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Pharmacology
  • Cell biology
1. Complementation assay
2. BRET
3. GPCR
1. orphan GPCR
2. Endocrinology
3. Metabolism
Rovira Xavier
Medicinal Chemistry & Synthesis group
Institute for Advanced Chemistry of Catalonia (IQAC)
Spanish National Research Council (CSIC)
ESwg1, wg3, wg51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Photochemistry
  • Pharmacology
  • Cell biology
  • Structural
1. Molecular pharmacology
2. Receptor signalling
3. Ligand-receptor interactions
1. Photopharmacology
2. GPCR
3. Bias Signalling
Brünle Steffen
Paul Scherrer Institute
CHwg1, wg2, wg3, wg4, wg51. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Structural
  • Biophysical
  • Biochemical
1. Protein X-ray Crystallography, Cryo-EM
2. Time-resolved X-ray crystallography
3. GPCR Signal Transduction
1. Structural Biology on GPCRs
2. Allosteric Modulation of GPCRs
3. Drug-discovery
Autore Flavia
Sosei-Heptares
CHwg1, wg2, wg3, wg4, wg51. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Biochemistry
  • Structural
  • Biochemical
  • Cell biology
Minos Matsoukas
University of Patras
GRwg1, wg31. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Biocomputing and molecular computation
3. Bioinformatics
  • Computational
  • Structural
  • Pharmacology
Maiju Rinne
University of Helsinki
FIwg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Medicinal chemistry

  • Pharmacology

  • Computational

  • Biochemical

1. Drug discovery
2. Structure modeling
3. Signaling pathways
1. GPCR evolution
2. Orexin system
3. Structural modeling
Christoffer K. Goth
University of Copenhagen
DKwg2, wg3, wg41. Cell signalling and signal transduction
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Glycobiology
  • Cell biology
  • Pharmacology
  • Biochemical

1. Chemokine receptors
2. Post translation modifications
3. Biased signaling
Rebeca Diez-Alarcia
University of the Basque Country UPV/EHU
Website
ESwg1, wg2, wg31. Neural cell function, communication and signalling, neurotransmission
2. Psychiatric disorders
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Biochemical
  • Animal models

1. Neuropyschopharmacology
2. GPCR
3. Cell signaling
Jesús Giraldo
Universitat Autònoma de Barcelona
Website
ESwg1, wg2, wg31. Biocomputing and molecular computation
2. Molecular mechanisms of signalling pathways
3. Biological chemistry
  • Computational
  • Pharmacology
  • Chemistry

1. GPCR allostery and dynamics
2. Quantitative pharmacology
3. Drug design
1. GPCR oligomerization
2. GPCR allostery
3. GPCR dynamics
Linda Johansson
University of Gothenburg
SEwg1, wg2, wg31. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Molecular mechanisms of signalling pathways
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Structural
  • Biophysical
  • Pharmacology

1. Crystallography
2. Cryo-EM
3. Signaling assays
1. Structural determination of GPCRs
2. GPCR dimerization
3. Orphan GPCRs
Jacopo Tricomi
University of Florence
ITwg11. Organic chemistry
2. Glycobiology
3. Biological chemistry
  • Chemistry
  • Computational
  • Computational

AYDIN Banu
Marmara University School of Medicine
TRwg2, wg31. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Cell biology
  • Biochemical
  • Pharmacology
1. Cell culture
2. Signal transduction cascades
3. RNA, DNA expression
1. cell signaling
2. cell proliferation
3. cancer molecular biology
Christa Müller
University of Bonn
Website
DEwg1, wg2, wg3,wg41. Medicinal chemistry
2. Biological chemistry
3. Cell signalling and signal transduction
  • Chemistry
  • Pharmacology
  • Cell biology

1. Drug development
2. GPCRs and ectonucleotidases
3. Purinergic signaling
1. Purines and their membrane targets
2. Orphan GPCRs
3. Ectonucleotidases
Szalai Bence
Semmelweis University
HUwg1, wg21. Systems biology
2. Computational biology
3. Transcriptomics
  • Computational
  • Pharmacology
  • Computational
1. perturbation transcriptomics
2. cancer drug sensitivity
3. machine learning
1. perturbation gene expression profiles
2. role in GPCRs in cancer
3. drug repurposing
Georgi Kanev
InterAx
CHwg1, wg41. Artificial intelligence, intelligent systems, multi agent systems
2. Bioinformatics
3. Structural biology and its methodologies
  • Computational
  • Structural
  • Chemistry
1. Machine learning
2. Ligand binding
3. Cheminformatics
1. Deep learning
2. Virtual screening
3. ADRB2
Marta Busnelli
CNR
ITwg1, wg2, wg31. Cell signalling and signal transduction
2. Biological chemistry
3. Neural cell function, communication and signalling, neurotransmission
  • Pharmacology
  • Biochemical
  • Animal models
1. oxytocin/vasopressin receptor
2. functional selective agonists
3. cell signalling
Belgin BUYUKAKILLI
Mersin University
TRwg21. Physics of biological systems
2. Neural cell function, communication and signalling, neurotransmission
3. Neurological disorders
  • Biophysical
  • Animal models
  • Biophysical
1. Neurobiopyhsics
2. ischemia-reperfusion, alzheimer
3. Cell biophysic
1. Motor dysfunction
2. Neuropathy
3. Hypoxic-ischemic injury
Maxime Louet
Université de Montpellier
FRwg1, wg31. Molecular architecture and structure
2. Theoretical and computational chemistry
3. Physics of biological systems
  • Computational
  • Structural
  • Biophysical
1. Molecular Modeling
2. Membrane protein structure
3. Conformational ensemble
1. GPCR
2. protein-protein interactions
3. protein motions
Nicolas Floquet
Centre National de la Recherche Scientifique (CNRS)
FRwg1, wg31. Molecular architecture and structure
2. Theoretical and computational chemistry
3. Physics of biological systems
  • Computational
  • Structural
  • Biophysical
1. Molecular Dynamics Simulations
2. Analysis of Structures
3. Conformational ensembles
1. GPCR
2. protein-protein interactions
3. ligand design and selectivity
Bernard Masri
Institut Cochin - INSERM U1016
FRwg1, wg31. Molecular aspects of endocrinology
2. Fundamental mechanisms underlying cancer
3. Fundamental mechanisms underlying cardiovascular diseases
  • Cell biology
  • Pharmacology
  • Computational
1. Resonance Energy Transfer 1. GPCR
2. Signaling
3. Cancer
Rita Melo
Instituto Superior Tecnico
PTwg1, wg3, wg4,wg51. Theoretical and computational chemistry
2. Computational biology
3. Machine learning
  • Biochemical
  • Structural
  • Computational
1. drug design
2. protein-protein interface
3. machine learning
1. molecular modeling
2. protein-protein interface
3. machine learning
Necla Birgül
Bogazici University
TRwg21. Molecular genetics, reverse genetics, forward genetics, genome editing
2. Computational biology
3. Cell signalling and signal transduction
  • Cell biology
  • Structural
  • Behavioral
1. Cell culture
2. Molecular Dynamic and Simulation
3. Knock-out
1. Deorphanising GPCRs
2. CRISPR/Cas9 technology
3. Purification of ligands
Nuska Tschammer
Crelux, a WuXi AppTec Company
DEwg41. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Medicinal chemistry
3. Pharmacology and pharmacogenomics
  • Biophysical
  • Biochemical
  • Structural
1. MicroScale Thermophoresis
2. FRET
1. Target-to-hit
2. DNA encoded libraries
3. Fragment screening
Claudia Stäubert
Leipzig University, Medical Faculty
DEwg1, wg2,1. Cell signalling and signal transduction
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Pharmacology
  • Cell biology
1. Metabolism
2. GPCR
1. GPCR
2. Signaling, trafficking
3. Evolution, metabolism
Lucie Pellissier
PRC UMR INRAE CNRS university of Tours
FRwg1, wg2, wg3,wg41. Pharmacology and pharmacogenomics
2. Psychiatric disorders
3. Neuronal development, plasticity and regeneration
  • Pharmacology
  • Animal models
  • Cell biology
1. RNAseq
2. BRET
1. Autism
2. Oxytocin
Desislava Nesheva
University of Nottingham
UKwg31. Pharmacology and pharmacogenomics
2. Regulation and effector functions of the immune response
3. Medicinal chemistry
  • Pharmacology
  • Cell biology
  • Biochemical
1. In vitro signalling assay, ligand binding in vitro
2. Cell culture, molecular cloning
3. ELISA
1. GPCR pharmacology
2. Cell signalling
3. Chemokines
Mr. Jack Lochray
University of Nottingham
UKwg1, wg2, wg3, wg4, wg51. Cell signalling and signal transduction
2. Molecular biophysics
3. Biological chemistry
  • Pharmacology
  • Cell biology
  • Biophysical
Dr. Laura Humphrys
Universität Regensburg
DEwg1, wg2, wg3, wg4, wg51. Cellular and Developmental Biology
2. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Neuroscience and Neural Disorders
  • Pharmacology
  • Cell biology
  • Biochemical
1. GPCR
Dr. Biljana Stankovic
Institute of molecular genetics and genetic engineering University of Belgrade
RSwg51. Bioinformatics
2. Biostatistics
3. Genomics
  • Computational
  • Cell biology
  • Pharmacology
1. Programming
2. Functional genomics
3. Drug-gene interactions
1. Bioinformatics
2. Pharmacogenomics
3. Biomedicine
Dr. Nikola Kotur
Institute of Molecular Genetics and Genetic Engineering
RSwg51. Genetics, ’Omics’, Bioinformatics and Systems Biology
  • Cell biology
  • Clinical
  • Computational
Mr. Leonhard Schink
Biotechnologie Institut Thurgau an der Universität Konstanz
Website
DEwg1, wg2, wg3, wg4, wg51. Organelle biology and trafficking
2. Molecular mechanisms of signalling pathways
3. Adaptive immunity
  • Cell biology
  • Animal models
  • Biochemical
Bradley Hoare
University of Nottingham
UKwg1, wg2, wg3, wg41. Biochemistry
2. Cell signalling and signal transduction
3. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions
  • Pharmacology
  • Biochemical
  • Cell biology
Ms. Nicola Dijon
University of Nottingham
UKwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Mathematics
3. Mathematics
  • Computational
  • Computational
  • Computational
Christoph Matti
Biotechnology Institute at the University of Konstanz
CHwg1, wg2, wg41. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Cellular and Developmental Biology
3. Immunity and Infection
  • Biochemical
  • Cell biology
  • Chemistry
1. Confocal Micrscopy
2. BRET
3. Protein production and cellular assays
Lisa Forster
University of Regensburg
DEwg1, wg2, wg3, wg4,wg51. Medicinal chemistry
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Pharmacology
  • Biochemical
  • Cell biology
1. Assay development
2. Unraveling of signalling pathways
Graeme Milligan
University of Glasgow
UKwg1, wg41. Mathematics
2. Mathematics
3. Mathematics
  • Computational
  • Computational
  • Computational
Atakan Aydin
Max-Delbrück-Center
DEwg21. Biological chemistry
2. Medicinal chemistry
3. Systems biology
  • Cell biology
  • Pharmacology
  • Animal models
Pawel Krawinski
Trinity College Dublin
IEwg1, wg41. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Biochemistry
  • Structural
  • Biochemical
  • Computational
Nicoli Alessandro
Leibniz-Institut für Lebensmittel-Systembiologie an der Technischen Universität München
DEwg41. Theoretical and computational chemistry
2. Molecular architecture and structure
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
1. MD, Homology Modelling

Schulte Gunnar
Karolinska Institute
SEwg2, wg31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Pharmacology
  • Biochemical
  • Biophysical
1. WNT
2. Frizzled
3. GPCR
Casajuana-Martin Nil
Universitat Autonoma Barcelona
ESwg1, wg31. Bioinformatics
2. Scientific computing, simulation and modelling tools
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational
1. Molecular dynamics
2. Homology modeling
3. Data analysis
1. GPCR activation
2. Molecular simulations
3. GPCR Oligomerization
Sykes David
University of Nottingham
GBwg1, wg2, wg3, wg41. 7. Physiology, Pathophysiology and Endocrinology
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. 8. Neuroscience and Neural Disorders
  • Pharmacology
  • Cell biology
  • Biochemical
1. GPCRs
2. Cell Signalling
3. FRET & BRET
1. GPCRs
2. Cell SIgnalling
3. Biophysical techniques
Milicevic Jelena
Vinča Institute of Nuclear Sciences
RSwg31. Organic chemistry
2. Medicinal chemistry
3. Physical chemistry
  • Computational
  • Computational
  • Computational
Honkisz-Orzechowska Ewelina
Jagiellonian University
PLwg1, wg2, wg3, wg4, wg51. Molecular mechanisms of signalling pathways
2. Morphology and functional imaging of cells and tissues
3. Neurological disorders
  • Cell biology
  • Pharmacology
  • Biochemical
1. neuroprotection
2. GPR18
3. autophagy
Holliday Nicholas
University of Nottingham
GBwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Biochemical
  • Cell biology
1. GPCR signalling
2. kinetics
3. molecular pharmacology
Mega Tiber Pinar
Marmara University, School of Medicine
TRwg1, wg2, wg31. Cell signalling and signal transduction
2. Cell death (including senescence) and autophagy
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Cell biology
  • Biophysical
  • Pharmacology
1. Cell culture and apoptosis assay
2. Western Blotting
3. in vitro assays
1. Cell signaling and signal transduction
2. Cell death
Mokrosinski Jacek
University of Cambridge
GBwg1, wg21. Molecular mechanisms of signalling pathways
2. Metabolism, biological basis of metabolism-related disorders
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Cell biology
  • Biochemical
Brocos-Mosquera Iria
University of the Basque Country
ESwg1, wg2, wg31. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology
3. 8. Neuroscience and Neural Disorders
  • Pharmacology
  • Biochemical
  • Cell biology
Ulven Trond
University of Copenhagen
DKwg31. Medicinal chemistry
2. Lipid biology
3. Organic chemistry
  • Chemistry
  • Pharmacology
  • Computational
Kurt Mehmet Hanifi
SEwg1, wg2, wg31. Scientific computing, simulation and modelling tools
2. Macromolecular complexes
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Computational
  • Biophysical
  • Structural
Llinas del Torrent Claudia
Universitat Autonoma Barcelona
ESwg1, wg2, wg3, wg51. Bioinformatics
2. Macromolecular complexes
3. Molecular mechanisms of signalling pathways
  • Computational
  • Biochemical
  • Pharmacology
Jiménez-Rosés Mireia
University of Nottingham
GBwg1, wg3, wg41. Scientific computing, simulation and modelling tools
2. Bioinformatics
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Computational
  • Computational
  • Structural
1. Molecular dynamic simulations
2. Virtual screening
3. Structure-Based Drug Discovery
Cunningham Margaret
University of Strathclyde
UKwg2, wg31. Molecular mechanisms of signalling pathways
2. Fundamental mechanisms underlying cardiovascular diseases
3. Cell signalling and signal transduction
  • Pharmacology
  • Cell biology
  • Biochemical
1. Pharmacology
2. Receptor trafficking
3. Protein-protein interaction techniques
1. Cardiovascular GPCRs

Gustavsson Martin
University of Copenhagen
DKwg1, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Macromolecular complexes
3. Molecular mechanisms of signalling pathways
  • Structural
  • Biochemical
  • Structural
1. Crystallography
2. Binding and signaling assays
3. NMR
1. Receptor structure and dynamics
2. Receptor:ligand interactions
3. Chemokine receptors
Hesse Sarah
University of Glasgow
GBwg2, wg3, wg51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Neurological disorders
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Pharmacology
  • Animal models
1. M1 muscarinic receptor
2. ligand in vitro characterisation
3. Alzheimer disease models
1. Drug studies
2. Microscopy
3. Animal Models
Eckel Juergen
Center of Competence for Innovative Diabetes Therapy - KomIT
DEwg2, wg31. 7. Physiology, Pathophysiology and Endocrinology
2. 10. Applied Medical Technologies, Diagnostics, Therapies and Public Health
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Biochemical
  • Cell biology
  • Pharmacology
1. Physiology of signal transduction
2. Diabetes and metabolic syndrome
3. Drug development
Stoeger Verena
wg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Molecular genetics, reverse genetics, forward genetics, genome editing
3. Molecular aspects of endocrinology
  • Cell biology
  • Biochemical
  • Pharmacology
1. CRISPR/Cas9, stable/transient transfections, ddPCR
2. ELISA, FACS, IHC, Western Blot
3. human intervention studies, organ tissue bath, homolgy modelling, docking
1. signal transduction peripheral taste & odor receptors
2. functional role of the peripheral sensory system
Granier Sebastien
INSERM
FRwg1, wg31. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Biochemical
  • Structural
  • Pharmacology
Ardévol Anna
Universitat Rovira i Virgili
ESwg2, wg31. Food sciences
2. Metabolism, biological basis of metabolism-related disorders
3. Molecular aspects of endocrinology
  • Biochemical
  • Animal models
  • Cell biology
1. Enterohormones
2. Rat
3. Ussing chamber
1. Ecnomotopic Taste receptors
2. Gastrointestinal tract
3. Enterohormone secretion
Rodríguez Gallego Esther
Universitat Rovita i Virgili
ESwg2, wg3, wg41. Biochemistry
2. Molecular mechanisms of signalling pathways
3. Metabolism, biological basis of metabolism-related disorders
  • Biochemical
  • Cell biology
  • Animal models
1. western blot
2. electron microscopy
3. nutritional studies
1. metabolism
2. autophagy
3. biomarkers discovery
Oz Arslan Devrim
Acibadem University
TRwg1, wg21. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Molecular mechanisms of signalling pathways
3. Cell signalling and signal transduction
  • Cell biology
  • Biochemical
  • Biophysical
1. Cellular imaging
2. Western blot
3. Protein interaction
1. Cellular signalling mechanisms
2. Autophagy
3. Mitochondrial dynamics
Allikalt Anni
FAU Erlangen-Nürnberg
DEwg1, wg3, wg41. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Medicinal chemistry
3. Neurological disorders
  • Pharmacology
  • Structural
  • Biochemical
1. Ligand binding assays
2. Protein expression and purification
3. Novel compounds
1. Structural biology
2. Structure based design
3. Novel methods
Peach Chloe
Centre of Membrane Proteins and Receptors, University of Nottingham
GBwg1, wg2, wg41. Molecular mechanisms of signalling pathways
2. 6. Cellular and Developmental Biology
3. 7. Physiology, Pathophysiology and Endocrinology
  • Pharmacology
  • Cell biology
  • Pharmacology
1. Receptor Tyrosine Kinases
2. G Protein-Coupled Receptors
3. Spatiotemporal Dynamics
Arrate Itziar
Unibersity of the Basque Country
ESwg1, wg2, wg31. Cell cycle, division and growth
2. Psychiatric disorders
3. Neural cell function, communication and signalling, neurotransmission
  • Pharmacology
  • Biochemical
  • Cell biology
1. gprc
2. Biased agonism
3. serotonin 2A receptor
Ullrich Annika
Friedriach-Alexanderuniversuität Erlangen-Nürnberg
DEwg1, wg31. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Structural
  • Pharmacology
  • Biochemical
1. structure determination
2. interactions
3. signaling pathway
Navarro Brugal Gemma
University of Barcelona
ESwg1, wg2, wg31. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Cell biology
  • Pharmacology
1. GPCR
2. Drug adiction
3. neurodegeneration
Rivas Santisteban Rafael
Universitat de Barcelona
ESwg11. Macromolecular complexes
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Pharmacology
  • Biochemical
  • Cell biology
Lillo Jové Jaume
Universitat de Barcelona
ESwg11. Macromolecular complexes
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Pharmacology
  • Biochemical
  • Cell biology
Lillo Marquez Alejandro
University of Barcelona
ESwg1, wg2, wg31. Neurological disorders
2. Immunological mechanisms in disease
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Pharmacology
  • Animal models
1. Neuroscience
2. Neurodegeneration
3. Autoimmunity
JEAN-ALPHONSE Frederic
CNRS-INRAE
FRwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Molecular aspects of endocrinology
  • Pharmacology
  • Cell biology
  • Pharmacology
1. cAMP
2. Imaging
3. biased ligands
1. GPCR
2. Endosomes
3. Gonadotropins
Orun Oya
Marmara University School of Medicine
TRwg2, wg31. Molecular mechanisms of signalling pathways
2. Quantitative genetics
3. Cell signalling and signal transduction
  • Cell biology
  • Biophysical
  • Biochemical
1. recombinant DNA tech, cloning
2. protein purification, FRET
3. gene and protein quantification methods
1. molecular biology of cancer
2. genetic regulations
3. cell signaling
Cecon Erika
Istitut Cochin, CNRS, INSERM, Université de Paris
FRwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Metabolism, biological basis of metabolism-related disorders
  • Cell biology
  • Pharmacology
  • Animal models
Ding Tianyi
Queen's University of Belfast
GBwg1, wg2, wg3, wg4, wg51. Macromolecular chemistry
2. Molecular architecture and structure
3. 2. Physics and Chemistry
  • Pharmacology
  • Computational
  • Biochemical
Casanovas Ferrero Mireia
University of Barcelona
ESwg1, wg2, wg31. Biochemistry
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Neurological disorders
  • Biochemical
  • Pharmacology
  • Cell biology
1. GPCR
2. addiction
Ben Shoshan-Galeczki Yaron
Hebrew university of Jerusalem
ILwg1, wg3, wg41. Food sciences
2. Bioinformatics
3. Biochemistry
  • Computational
  • Structural
  • Biochemical
1. Docking
2. Modeling
3. Sugars
1. Sweet taste receptor
2. Docking
3. MD
Decker Michael
Universität Würzburg
DEwg31. Medicinal chemistry
2. Neurological disorders
3. Organic chemistry
  • Chemistry
  • Pharmacology
  • Computational
1. organic
2. in vitro
1. Alzheimer's disease
2. Photopharmacology
3. Hybrid molecules
Schmidt Esther
Boehringer Ingelheim Pharma GmbH & Co KG
DEwg2, wg3, wg41. Cell signalling and signal transduction
2. Psychiatric disorders
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Cell biology
  • Pharmacology
  • Pharmacology
1. label-free holistic cell analysis
2. high throughput screening
3. MALDI-based binding assays for membrane proteins
1. orphan GPCRs
2. immunology
3. psychiatric disorders
Steinmüller Sophie
Julius-Maximilians-Universität Würzburg
DEwg31. Medicinal chemistry
2. Photochemistry
3. Neurological disorders
  • Chemistry
  • Chemistry
  • Pharmacology
1. Synthesis
2. Photochemical GPCR ligand switches
3. In vitro assays (CB Receptors)
1. Cannabinoid Ligands
2. Pharmacology / Molecular mechanisms of signalling pathways
3. Photochemistry
Sink Alexandra
Julius-Maximilians-Universität Würzburg
DEwg31. Medicinal chemistry
2. Organic chemistry
3. Photochemistry
  • Chemistry
  • Chemistry
  • Chemistry
1. Synthesis
2. Ligand design
3. Photochemical switches
1. Pharmacology
2. Molecular mechanism of signalling pathways
3. Cardiovascular disease
Spatz Philipp
Julius-Maximilians-University Würzburg
DEwg1, wg2, wg31. Medicinal chemistry
2. Organic chemistry
3. Neurological disorders
  • Chemistry
  • Chemistry
  • Chemistry
1. Ligand design
2. fluorine incorporation
3. linkage and merge of pharmacophores
1. Tracer development (PET)
2. AD treatment
Gerwe Hubert
Universität Würzburg
DEwg2, wg3, wg41. Medicinal chemistry
2. Organic chemistry
3. Photochemistry
  • Chemistry
  • Chemistry
  • Pharmacology
1. Ligand Design and Synthesis
2. Photochemical Switches
3. Photopharmacology
1. GPCR Dynamics
2. Photochemistry of GPCR Ligands
3. Cardiovascular Diseases
Tutov Anna
Julius-Maximilians-Universität Würzburg
DEwg31. Medicinal chemistry
2. Organic chemistry
3. Molecular mechanisms of signalling pathways
  • Chemistry
  • Chemistry
  • Pharmacology
1. Synthesis
2. Organic Chemistry
3. in vitro assays
1. Cannabinoid Receptors
2. Muscarinic Receptor M1
3. Positron Emission Tomography
Shekhani Rawan
Karolinska Institutet
SEwg1, wg2, wg3, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Kukkonen Jyrki
University of Helsinki
FIwg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Scientific computing, simulation and modelling tools
  • Pharmacology
  • Cell biology
  • Biochemical
1. Binding and concentration response analyses
2. Interaction of the pathways
1. GPCR signalling and pharmacology
2. Lipid messengers
3. orexins
VANDERMOERE Franck
CNRS
FRwg1, wg2, wg41. Proteomics
2. Molecular mechanisms of signalling pathways
3. Bioinformatics
  • Biophysical
  • Biophysical
  • Biophysical
1. Mass spectrometry
2. Phosphoproteomics
3. Interactomics
1. GPCRs
2. Proteomics
3. Signaling
Evenseth Linn S.M.
Philipps-Universität Marburg
DEwg1, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular mechanisms of signalling pathways
3. Scientific computing, simulation and modelling tools
  • Computational
  • Computational
  • Cell biology
1. Virtual screening
2. Molecular Dynamics
Wang Ziming
Max-Delbruck-Center for Molecular Medicine
DEwg1, wg2, wg3, wg4, wg51. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Cell junctions, cell adhesion, cell communication and the extracellular matrix
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Biophysical
  • Cell biology
Rabe Philipp
University Leipzig
DEwg1, wg21. Biochemistry
2. Molecular mechanisms of signalling pathways
3. Cell signalling and signal transduction
  • Biochemical
  • Cell biology
  • Pharmacology
2. Signal transduction
1. Cancer
2. Signal transduction
3. Subcellular localization
Klenk Christoph
University of Zurich
CHwg1, wg3, wg41. Molecular mechanisms of signalling pathways
2. Macromolecular complexes
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biochemical
  • Pharmacology
  • Structural
1. Directed evolution
2. Ligand binding
3. X-ray crystallography
1. Class B GPCRs
2. Structure-function mechanisms
3. Drug development
Olgac Abdurrahman
Gazi University Faculty of Pharmacy
TRwg1, wg3, wg51. Medicinal chemistry
2. Biocomputing and molecular computation
3. Molecular mechanisms of signalling pathways
  • Chemistry
  • Computational
  • Structural
1. Medicinal Chemistry
2. Computer Aided Drug Design
3. Regulation of Dimerization
1. Leukotrienes
2. GPCRs
3. Prostaglandins
Giorgino Toni
CNR
ITwg4, wg51. Computational biology
2. Physics of biological systems
3. Macromolecular chemistry
  • Computational
  • Computational
  • Computational
1. Molecular dynamics
2. Biostatistics
3. Data mining
1. Molecular dynamics
2. Biostatistics
3. Data mining
Latek Dorota
University of Warsaw
PLwg1, wg51. Computational biology
2. Molecular architecture and structure
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Computational
  • Structural
  • Pharmacology
1. integrative structural biology
2. molecular dynamics
3. drug discovery
durer zeynep
Acibadem MAA University
TRwg1, wg41. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Proteomics
3. Cytoskeleton and cell behaviour
  • Biochemical
  • Biophysical
  • Structural
1. Adhesion proteins
2. Actin cytoskeleton and binding proteins
3. Conformational dynamics of proteins
Shapiro Tuchman Ziva
University of Haifa
ILwg1, wg2, wg31. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Pamula Filip
ETH
CHwg1, wg2, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Macromolecular complexes
3. Biocomputing and molecular computation
  • Biochemical
  • Structural
  • Biophysical
1. Membrane protein
2. cryo-EM
3. Spectroscopy
1. Membrane biology
2. GPCR
3. Molecular machines
Umbach Simon
Goethe Universität Frankfurt
DEwg1, wg2, wg3, wg4, wg51. Biochemistry
2. Protein synthesis, modification, turnover
3. Fundamental aspects of synthetic biology and chemical biology
  • Biochemical
  • Cell biology
  • Biophysical
1. Protein-Ligand Interaction

3. Cell-free protein synthesis
Lemel Laura
University of Nottingham
GBwg21. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Computational
  • Computational
  • Computational
1. Cell biology
2. Pharmacology
Budvytyte Rima
vilnius UNIVERSITY
LTwg41. Physical chemistry of biological systems
2. Biochemistry
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Biophysical
  • Biophysical
  • Biochemical
1. electrochemical impedance spectroscopy
2. Atomic force microscopyc
3. surface plasmon resonance
1. lipid membrane
2. channels
3. protein-lipid interactions
Chavez Abiega Sergei
University of Amsterdam
NLwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Bioinformatics
  • Cell biology
  • Pharmacology
  • Biochemical
Schneider Johannes
Friedrich-Alexander Universität Erlangen-Nürnberg
DEwg1, wg2, wg3, wg41. Medicinal chemistry
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Biochemical
  • Structural
1. Functional Selectivity
2. Novel biased ligands
3. GPCR dynamics
DAM Julie
University Paris Descartes , INSERM, CNRS
FRwg1, wg2, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular mechanisms of signalling pathways
3. Metabolism, biological basis of metabolism-related disorders
  • Pharmacology
  • Cell biology
  • Animal models
1. GPCR
2. Leptin receptor
3. energy transfer technologies
lin jerry
wmu
wg1, wg2, wg3, wg4, wg51. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Theoretical and computational chemistry
  • Computational
  • Computational
  • Computational
Deganutti Giuseppe
Coventry University
GBwg1, wg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Theoretical and computational chemistry
3. Macromolecular complexes
  • Biophysical
  • Computational
  • Structural
1. simulations
2. chemistry
3. biology
1. Atomistic simulations
2. Non-equilibrium simulations
3. Drug design
Majellaro Maria
University of Santiago de Compostela
ESwg31. Organic chemistry
2. Medicinal chemistry
3. Method development in chemistry
  • Chemistry
  • Chemistry
  • Chemistry
1. medicinal chemistry

1. Synthesis of GPCR ligands
2. multicomponent reactions
Carofiglio Francesca
Università degli Studi di Bari "Aldo Moro"
ITwg31. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Baloglu Emel
Acibadem Mehmet Ali Aydinlar University
TRwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Cell biology
  • Biochemical
1. drug development, ligand classification
2. treatment
3. cellular signaling
1. GPCR signaling
2. lung
3. heart
Guseinov Abdul-Akim
Queen's University Belfast, School of Pharmacy
GBwg1, wg3, wg41. Medicinal chemistry
2. Scientific computing, simulation and modelling tools
3. Macromolecular complexes
  • Computational
  • Pharmacology
  • Chemistry
1. Molecular modelling in drug design
2. Pharmacological assays
3. Organic Synthesis
1. Molecular modelling
2. Computer-aided drug design
3. Pharmacological assays
Kooistra Albert
University of Copenhagen
DKwg1, wg51. Computational biology
2. Web and information systems, database systems
3. Bioinformatics
  • Computational
  • Structural
  • Pharmacology
1. Cheminformatics, database development, and predictive modeling
2. Structural bioinformatics
3. Structure-based drug design and optimization
1. Cheminformatics, database development, and predictive modeling
2. Structure-based drug design and optimization
3. (Structural) bioinformatics
Morales Paula
Spanish National Research Council
ESwg3, wg51. Medicinal chemistry
2. Molecular architecture and structure
3. Biological chemistry
  • Computational
  • Chemistry
  • Biophysical
1. Molecular modeling
2. Synthesis
3. Protein NMR
1. Cannabinoid receptors
2. orphan GPCRs
3. Endocannabinoid signaling
Vila Julià Guillem
Polytechnic University of Barcelona
ESwg41. 3. Computer Science and Informatics
2. Scientific computing, simulation and modelling tools
3. Bioinformatics
  • Computational
  • Computational
  • Computational
Veerman Ben
University of Strathclyde
GBwg1, wg2, wg3, wg4, wg51. Fundamental mechanisms underlying cardiovascular diseases
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Cell biology
  • Pharmacology
1. Connexin-43
2. PAR-1
3. Doxorubicin
1. Cardiovascular
2. Toxicity
3. Exosomes
Jasko Piotr
PLwg1, wg2, wg3, wg41. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular mechanisms of signalling pathways
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Pharmacology
  • Biochemical
  • Biophysical
1. Radioligand binding assays
2. Cell-based assays
3. NMR
1. GPCRs
2. Protein structure and dynamics
3. Cell signaling pathways
Hoxha Malvina
Catholic University Our Lady of Good Counsel
ALwg51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Fundamental mechanisms underlying cardiovascular diseases
3. Epidemiology and public health
  • Pharmacology
  • Clinical
  • Cell biology
1. Pharmacology
2. Pharmacotherapy
Castro Marián
University of Santiago de Compostela
ESwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Psychiatric disorders
  • Pharmacology
  • Cell biology
  • Pharmacology
1. GPCR ligand binding and signalling
2. FRET/BRET
3. in vitro/cell-based assays and HTS
1. binding kinetics, ligand bias
2. signal compartmentalization
3. allosterism, early drug discovery
Kolocouris Antonios
National and Kapodistrian University of Athenss
GRwg31. Medicinal chemistry
2. Scientific computing, simulation and modelling tools
3. Organic chemistry
  • Chemistry
  • Computational
  • Biophysical
1. computer aided drug design, computational organic chemistry, synthesis of drug molecules
2. MD simulations, binding free energy calculations, DFT calculations
3. NMR, SAXS, DSC
1. computational design of adenosine receptor binders, MmpL3 transporter inhibitors against TB, influenza A M2 modulation M2 , P2X7 binders
2. Protein - lipid interactions
3. DFT calculations of weak hydrogen bonding and DFT-based mechanistic organic chemistry
Gupta Shailendra
University of Rostock
DEwg1, wg2, wg3, wg51. Scientific computing, simulation and modelling tools
2. Systems biology
3. Immunological mechanisms in disease
  • Computational
  • Structural
  • Biophysical
1. Mathematical modeling
2. Pharmacophore modeling
3. Docking and simulation
1. Disease maps
2. GPCRs
3. Drug repositioning
PONIMASKIN EVGENI
Hanover Medical School
DEwg1, wg41. Neural cell function, communication and signalling, neurotransmission
2. Neuronal development, plasticity and regeneration
3. Fundamental mechanisms underlying ageing
  • Cell biology
  • Biophysical
  • Pharmacology
1. quantitative molecular microscopy
2. FRET
3. high-troughput screening
1. GPCR-mediated signaling
2. protein-protein interaction
3. post-translational protein modifications
Healey Robert
IGF, Univ. Montpellier, CNRS, INSERM
FRwg1, wg2, wg31. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Lipid biology
  • Structural
  • Biochemical
  • Biochemical
1. Crystallography
2. Protein purification
3. HTS ligand discovery
1. Membrane proteins
2. Drug discovery
3. Structural biology
Floquet Nicolas
Centre National de la Recherche Scientifique (CNRS), Université de Montpellier
FRwg11. Scientific computing, simulation and modelling tools
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Computational
  • Computational
  • Computational
1. Molecular Dynamics Simulations

1. GPCRs coupling to modulators
2. Molecular simulations
3. Structural features of selectivity
Severo Gomes Antoniel Augusto
Université de Montpellier
FRwg11. Scientific computing, simulation and modelling tools
2. Macromolecular complexes
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Structural
  • Computational
  • Biophysical
1. Molecular Modelling
2. Molecular Dynamics
3. Normal Modes
1. Protein Function
2. Biomolecular Interactions
3. Molecular Modelling
Lockington Hannah
University of Nottingham
GBwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Cell biology
  • Biochemical
Guthrie Brian
Cargill
BEwg1, wg2, wg3, wg41. Physics of biological systems
2. Physical chemistry of biological systems
3. Chemical physics
  • Biophysical
  • Chemistry
  • Computational
1. GPCR signal transduction
2. Class-C
3. Class-A
Hoffmann Carsten
University Hospital Jena
DEwg1, wg2, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Pharmacology
  • Cell biology
  • Biophysical
1. Molecular Pharmacology of GPCRs
2. real-time assays and imaging
3. Design of FRET/BRET based sensors
1. GPCR activation
2. arrestin
3. GRKs
Onat Filiz
Acibadem Mehmet Ali Aydinlar University
TRwg1, wg21. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
1. Absence epilepsy rat model
2. Receptors in epilepsy
3. Signaling in epilepsy
Zugaza José L.
Achucarro Basque Center for Neuroscience
ESwg2, wg31. Molecular mechanisms of signalling pathways
2. Biochemistry
3. Proteomics
  • Cell biology
  • Biochemical
  • Pharmacology
1. cellular functions in health and disease
2. post-translational modifications
3. Recombinant peptides
1. Small GTPases
2. Glycogen phosphorylase
3. Rare diseases
ARGYROU MINAS
AGRICULTURAL UNIVERSITY OF ATHENS
GRwg1, wg3, wg4, wg51. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology
3. 12. Applied Life Sciences and Biotechnology
  • Pharmacology
  • Cell biology
  • Biochemical
Noonan Theresa
Freie Universität Berlin
DEwg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Scientific computing, simulation and modelling tools
3. Molecular mechanisms of signalling pathways
  • Computational
  • Pharmacology
  • Structural
1. Molecular modelling
2. Computational drug design
3. Structure-based drug design
1. Allosteric modulation
2. GPCRs
3. Drug design
Talagayev Valerij
DEwg4, wg51. Biocomputing and molecular computation
2. Organic chemistry
3. Medicinal chemistry
  • Computational
  • Chemistry
  • Computational
1. GPCR
2. MD Simulations
3. Computational Chemistry
Kaminski Tim
InSingulo AB
SEwg41. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Surface science and nanostructures
  • Biophysical
  • Biophysical
  • Biophysical
1. biosensors
2. single-molecule approaches
3. GPCR
1. single-molecule biophysics
2. biosensing
3. membrane proteins
Mouillac Bernard
Institut de Génomique Fonctionnelle, Université Montpellier, CNRS, INSERM
FRwg1, wg2, wg41. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Molecular mechanisms of signalling pathways
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Pharmacology
  • Biochemical
  • Structural
1. GPCR
2. expression and purification of membrane proteins
3. cryo-electrom microscopy, NMR, cristallography
1. G protein-coupled receptors
2. signaling pathways
3. structure, dynamics
Gossert Alvar
ETH Zürich
CHwg1, wg3, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Biophysical
  • Structural
  • Computational
1. NMR
2. Protein-protein interaction
1. Drug discovery
2. Molecular interactions
Puls Kristina
Free University Berlin (Freie Universität Berlin)
DEwg3, wg41. Scientific computing, simulation and modelling tools
2. Medicinal chemistry
3.
  • Computational
  • Computational
  • Computational
1. virtual screening, Docking, Molecular dynamic simulations
2. static pharmacophores, dynamic pharmacophores (dynophores)
3. Homology modeling
1. Kappa Opioid receptor (GPCR)
2. Biased signaling
3. activation mechanism and subsequent signaling pathways
Alawa Majed
Freie Universität Berlin
DEwg1, wg2, wg3, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Rößler Philip
ETH Zürich
CHwg1, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Spectroscopic and spectrometric techniques
3. Macromolecular complexes
  • Structural
  • Biochemical
  • Computational
1. NMR Spectroscopy
2. Isotope Labelling
1. Receptor dynamics
2. G protein interactions
Denzinger Katrin
Freie Universität Berlin
DEwg1, wg3, wg51. Scientific computing, simulation and modelling tools
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Cell signalling and signal transduction
  • Computational
  • Computational
  • Computational
1. Molecular Modelling
2. GPCR
3. Functional Selectivity
Güney Sevin
Gazi University
TRwg1, wg2, wg3, wg4, wg51. Organ physiology and pathophysiology
2. Cell signalling and signal transduction
3. Organelle biology and trafficking
  • Cell biology
  • Biochemical
  • Animal models
1. western blot
2. oxidative stress parameters
3. stereotaxic surgery on rodents
1. opioid peptide receptors
2. cardiopulmonary physiology
Güney Sevin
Gazi University
TRwg1, wg2, wg3, wg4, wg51. Organ physiology and pathophysiology
2. Cell signalling and signal transduction
3. Organelle biology and trafficking
  • Cell biology
  • Biochemical
  • Animal models
1. western blot
2. oxidative stress parameters
3. stereotaxic surgery on rodents
1. opioid peptide receptors
2. cardiopulmonary physiology
Benkel Tobias
University of Bonn
DEwg1, wg2, wg3, wg4, wg51. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Cell biology
  • Biochemical
1. GPCRs
2. Signal transduction
3. Compartmentalization
Maccarrone Mauro
University of L'Aquila
ITwg1, wg31. Biochemistry
2. Molecular mechanisms of signalling pathways
3. Lipid biology
  • Biochemical
  • Pharmacology
  • Cell biology
1. Radiometric assays
2. FRAP
3. Enspire
1. Lipid signalling
2. Endocannabinoids
3. Resolvins
Banères Jean-Louis
CNRS
FRwg1, wg2, wg31. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Pharmacology
  • Biophysical
Scholz Nicole
Leipzig University
DEwg21. 7. Physiology, Pathophysiology and Endocrinology
2. 6. Cellular and Developmental Biology
3. Neural cell function, communication and signalling, neurotransmission
  • Animal models
  • Cell biology
  • Biochemical
1. Drosophila

1. Adhesion GPCR
2. Mechanobiology
3. Physiologie
Labani Nedjma
Institut Cochin
FRwg31. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Loebbert Arnelle
ETH Zurich
CHwg1, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Macromolecular complexes
3. Spectroscopic and spectrometric techniques
  • Biophysical
  • Structural
  • Computational
1. NMR

1. NMR
2. Arrestin, GRK
Verbakel Lina
KU Leuven
BEwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Molecular aspects of endocrinology
  • Animal models
  • Computational
  • Computational
1. RNAi-mediated knockdown

Kurt Han
SEwg1, wg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Computational biology
3. Machine learning
  • Computational
  • Structural
  • Biophysical
Al Hamwi Ghazl
University of Bonn
DEwg2, wg41. Cell signalling and signal transduction
2. Biochemistry
3. Biological chemistry
  • Pharmacology
  • Cell biology
  • Chemistry
1. Orphan GPCRs
2. Cell-based assays and HTS
3. Structure-activity relationship
Ulven Elisabeth Rexen
University of Copenhagen
DKwg3, wg41. Medicinal chemistry
2. Computational biology
3. Metabolism, biological basis of metabolism-related disorders
  • Chemistry
  • Computational
  • Computational
Staszewski Marek
Medical University of Lodz
PLwg2, wg31. Medicinal chemistry
2. Organic chemistry
3.
  • Chemistry
  • Animal models
  • Pharmacology
1. Synhtesis of GPCR ligands
2. In vitro assays
1. Drug design and synthesis
2. H3R, H1R, M2R/M3R ligands in vitro assays
3. SAR analysis
Bernhard Frank
Goethe University Frankfurt
DEwg41. Protein synthesis, modification, turnover
2. Biochemistry
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Biochemical
  • Structural
  • Pharmacology
1. Synthetic Biology
2. NMR techniques
3. GPCR ligand interactions
1. Cell-free synthesis of GPCRs
2. Nanoparticle technologies
3. GPCR engineering
Borrega Leire
Universidad del País Vasco/Euskal Herriko Unibertsitatea
ESwg1, wg2, wg3, wg4, wg51. Molecular mechanisms of signalling pathways
2. Neural cell function, communication and signalling, neurotransmission
3. Cell signalling and signal transduction
  • Pharmacology
1. Selective functionality
2. Kinetics of ligand
3. membrane cholesterol
Rovira Xavier
University of Vic - Central University of Catalonia
ESwg1, wg2, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Photochemistry
  • Pharmacology
  • Cell biology
  • Structural
1. Molecular pharmacology
2. Receptor signalling
3. Ligand-receptor interactions
1. Photopharmacology
2. GPCR
3. Bias Signalling
Wilhelm Florian
ETH Zürich
CHwg1, wg3, wg41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Biophysical
  • Pharmacology
  • Computational
Miranda Pastoriza Dario
Universidade de Santiago de Compostela
ESwg1, wg2, wg31. Medicinal chemistry
2. Biological chemistry
3. Biochemistry
  • Chemistry
  • Pharmacology
  • Structural
1. Multicomponent Reaction
2. Adenosine
3. Medicinal Chemistry
1. Drug discovery and development
2. Pharmacology
3. Medicinal Chemistry
Campos Prieto Lucía
University of Santiago de Compostela
ESwg2, wg3, wg51. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Rujan Roxana-Maria
Coventry University
GBwg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Computational biology
3. Molecular architecture and structure
  • Structural
  • Pharmacology
  • Behavioral
Liessmann Fabian
Leipzig University
DEwg3, wg41. Scientific computing, simulation and modelling tools
2. Medicinal chemistry
3. Computational biology
  • Computational
  • Computational
  • Computational
1. Homology modeling
2. Computational Medicinal Chemistry
3. Drug Discovery/Ultra-large library screening
1. Adhesion GPCRs
2. Computer-Aided Drug Discovery/Design
3. Biased Signaling
Jagerovic Nadine
Spanish National Research Council
ESwg3, wg51. Medicinal chemistry
2. Organic chemistry
3. Theoretical and computational chemistry
  • Chemistry
  • Chemistry
  • Computational
1. Cannabinoid Receptors
2. GPCRS-related to the Endocannabinoid System
3. Allosterism and Biased Signaling
Campbell Adrian
Sygnature Discovery
GBwg3, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Biophysical
  • Computational
Ramos Sofia
Universidade Lusófona
PTwg1, wg2, wg3, wg4, wg51. Cell signalling and signal transduction
2. Cell junctions, cell adhesion, cell communication and the extracellular matrix
3. Computational biology
  • Computational
  • Computational
  • Computational
Laboute Thibaut
University of Tours
FRwg1, wg2, wg31. Cell signalling and signal transduction
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Neural cell function, communication and signalling, neurotransmission
  • Pharmacology
  • Cell biology
  • Behavioral
1. BRET, FRET, HTRF, and other sensors
2. cell biology
3. mice behavioural assays
1. GPCRs
2. Nanobody
3. Neurosciences
Andújar Antonio
University of Santiago de Compostela
ESwg2, wg31. Medicinal chemistry
2. Theoretical and computational chemistry
3. Biological chemistry
  • Chemistry
  • Pharmacology
  • Computational
ERGUN Sercan
Ondokuz Mayıs University
TRwg21. Molecular mechanisms of signalling pathways
2. Non-coding RNAs
3. Epigenetics and gene regulation
  • Cell biology
  • Clinical
  • Pharmacology
1. Cancer signalling pathways
2. Epigenetics
3. Drug resistance
Wieser Mara
Paul Scherrer Institut
CHwg1, wg2, wg31.
2.
3.
  • Computational
  • Computational
  • Computational
Kahlous Nour Aldin
Uppsala University
SEwg1, wg2, wg3, wg41.
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
1. Drug discovery
2. Molecular dynamics
3. FEP
Walker Abigail
Imperial College London
GBwg1, wg2, wg31. Molecular aspects of endocrinology
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Macromolecular complexes
  • Cell biology
  • Biochemical
  • Computational
1. GPCR
2. Reproduction
3. Super-resolution
Kopanchuk Sergei
University of Tartu
EEwg2, wg41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Biophysical
  • Biophysical
  • Pharmacology
1. Fluorescence techniques (FI/FRET, FL, FA)
2. Microscopy techniques (TIRF, FCS, FLIM/TGL)
3. Kinetic modelling
1. Ligand binding kinetics
2. Single-molecule microscopy
3. Peptides and proteins GPCRs
Bergkamp Nick
Vrije Universiteit Amsterdam
NLwg1, wg21. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Cell biology
  • Pharmacology
  • Computational
Kniazeff Julie
CNRS, University of Montpellier
FRwg1, wg31. Molecular mechanisms of signalling pathways
2. Macromolecular complexes
3. Cell signalling and signal transduction
  • Pharmacology
  • Biophysical
  • Computational
Olechwier Agnieszka
Paul Scherrer Institute
CHwg1, wg2, wg3, wg4, wg51. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Cell signalling and signal transduction
  • Structural
  • Biophysical
  • Biochemical
Singh Rajiv
Okinawa Institute of Science and Technology, Japan
wg1, wg2, wg3, wg4, wg51. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Imaging for medical diagnosis
  • Structural
  • Biochemical
  • Cell biology
1. CryoEM and XRD
2. Molecular Biology and Biochemistry
3. Cell Signaling and Pharmacology
1. Chemoreceptors
2. CryoEM
3. Crystal Structure
Simon Katharina
University of Bonn
DEwg2, wg31. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Van den Driest Lisa
University of Strathclyde
GBwg1, wg2, wg3, wg4, wg51. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Qi Chao
ETH Zurich
CHwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Biochemistry
3. 1. Mathematics (applications in science and industry)
  • Structural
  • Biophysical
  • Biochemical
1. adenylyl cyclase

Guixà-González Ramon
Paul Scherrer institute
CHwg1, wg31. Scientific computing, simulation and modelling tools
2. 1. Mathematics (applications in science and industry)
3. Bioinformatics
  • Computational
  • Structural
  • Computational
1. Molecular dynamics simulations
2. Structural bioinformatics
3. Molecular modeling
1. GPCR-lipid interactions
2. GPCRs activation mechanism
3. GPCR-G protein recognition
Novikoff Aaron
Helmholtz-Zentrum München
DEwg1, wg2, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular mechanisms of signalling pathways
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Pharmacology
  • Cell biology
  • Biochemical
1. GLP-1
2. GPCR
1. Drug-development optimization
2. Dynamic Intracellular Signalling
Mahardhika Andhika
University of Bonn
DEwg2, wg41. Medicinal chemistry
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Chemistry
1. Orphan GPCRs
2. Tool compounds
3. Structure-activity relationship
PANNEELS Valerie
Paul Scherrer Institute
CHwg1, wg2, wg3, wg41. Molecular architecture and structure
2. Spectroscopic and spectrometric techniques
3. Physics of biological systems
  • Structural
  • Biochemical
  • Cell biology
1. GPCR
2. lipid
3. structure
Bondar Ana-Nicoleta
University of Bucharest
ROwg1, wg2, wg3, wg4, wg51. Physics of biological systems
2. Molecular architecture and structure
3. Theoretical and computational chemistry
  • Computational
  • Biophysical
  • Computational
1. graph theory
2. protein reaction mechanism
3. proton transfer
1. hydrogen bonding
2. protein conformational dynamics
3. pH sensing
Tóth András Dávid
Semmelweis University
HUwg2, wg41. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biochemical
  • Cell biology
  • Pharmacology
1. BRET
2. fluorescent imaging
3. signaling assays
1. GPCRs
2. biased signaling
3. arrestins
Collu Gabriella
Paul Scherrer Institut-ETH Zurich
CHwg1, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Biochemistry
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Structural
  • Biochemical
  • Computational
1. cryo-EM
2. membrane protein
Fernandez-Recio Juan
Consejo Superior de Investigaciones Científicas (CSIC)
ESwg1, wg41. Computational biology
2. Macromolecular complexes
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Computational
  • Biophysical
  • Structural
1. Protein-protein docking
2. Binding energy calculation
3. Structural modeling
1. Protein-protein interactions
2. Molecular modeling
3. Structural bioinformatics
Pan Kylie
InterAx Biotech AG and VU Amsterdam
CHwg2, wg31. Systems biology
2. Fundamental mechanisms underlying cancer
3. Cell signalling and signal transduction
  • Biochemical
  • Computational
  • Computational
Lombo Cristian
Julius-Maximilians-Universität Würzburg
DEwg1, wg2, wg31. Medicinal chemistry
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Cell signalling and signal transduction
  • Chemistry
  • Pharmacology
  • Cell biology
1. synthesis
2. assay
3. signaling
1. biased signaling
2. SAR
3. Networking
Zięba Agata
Medical University of Lublin
PLwg2, wg31. Theoretical and computational chemistry
2. Bioinformatics
3. 3. Computer Science and Informatics
  • Chemistry
  • Pharmacology
  • Clinical
Boardman Andrew
University of Cambridge
GBwg2, wg4, wg51. Bioinformatics
2. Machine learning
3. Computational biology
  • Computational
  • Structural
  • Biophysical
Claff Tobias
University of Bonn
DEwg1, wg21. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Macromolecular complexes
3. Fundamental aspects of synthetic biology and chemical biology
  • Structural
  • Biochemical
  • Cell biology
1. X-ray crystallography
2. Protein Purification
3. Insect cells and Expression
1. GPCR X-ray crystallography
2. Oligomerization of GPCRs
3. Adenosine Receptors
Scharf Magdalena M.
Philipps-Universität Marburg
DEwg1, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular mechanisms of signalling pathways
3. Scientific computing, simulation and modelling tools
  • Computational
  • Pharmacology
  • Structural
Lavogina Darja
University of Tartu
EEwg1, wg2, wg31. Biological chemistry
2. Medicinal chemistry
3. Biochemistry
  • Cell biology
  • Biochemical
  • Structural
Llavero Bernal Francisco
Instituto de Investigación Hospital 12 de Octubre. Madrid. Spain
wg21. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Molecular mechanisms of signalling pathways
3. Glycobiology
  • Biochemical
  • Cell biology
  • Pharmacology
Perez Almeria Claudia V.
Vrije Universiteit Amsterdam
NLwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Pharmacology
  • Cell biology
  • Biochemical
1. Molecular pharmacology GPCRs
2. Signal transduction
3. Microscopy
1. GPCR signalling
2. Nanobodies
3. Oncology
Podlewska Sabina
Maj Institute of Pharmacology Polish Academy of Sciences
PLwg31. Medicinal chemistry
2. 1. Mathematics (applications in science and industry)
3. Machine learning
  • Computational
  • Computational
  • Computational
1. molecular modeling
2. machine learning
3. docking
1. computer-aided drug design
2. machine learning
3. docking
Maslov Ivan
KU Leuven
BEwg41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Spectroscopic and spectrometric techniques
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Biophysical
  • Structural
  • Cell biology
Hogendorf Adam
Maj Institute of Pharmacology, Polish Academy of Sciences
PLwg2, wg3, wg41. Medicinal chemistry
2. Organic chemistry
3. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions
  • Chemistry
  • Pharmacology
  • Computational
1. serotonin system
2. glutaminergic system
3. psychopharmacology
Safitri Dewi
University of Cambridge
GBwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Metabolism, biological basis of metabolism-related disorders
  • Pharmacology
  • Cell biology
  • Animal models
1. BRET
2. cloning
1. GPCR
2. metabolic disorder
Delemotte Lucie
KTH Royal Institute of Technology
SEwg31. Physical chemistry of biological systems
2. Biocomputing and molecular computation
3. Bioinformatics
  • Computational
  • Structural
  • Biophysical
1. Molecular dynamics simulations

Underwood Owen
University of Nottingham
GBwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Pharmacology
  • Computational
1. BRET
2. Fluorescence Correlation Spectroscopy
1. opioid
2. beta-arrestin2
3. trafficking
Pérez-Conesa Sergio
Kungliga Tekniksa Hogskolan (KTH) Stockholm
SEwg3, wg4, wg51. Biocomputing and molecular computation
2. Theoretical and computational chemistry
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Computational
  • Biophysical
  • Pharmacology
1. Molecular Dynamics
2. Allosteric Modulation
3. Drug Design
1. Molecular Dynamics
2. Drug Design
3. Allosteric modulation.
Ma Xin
Technical University of Denmark
DKwg3, wg41. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. 12. Applied Life Sciences and Biotechnology
  • Computational
  • Computational
  • Computational
Patriarchi Tommaso
University of Zurich
CHwg1, wg2, wg3, wg41. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds)
2. Applied bioengineering, synthetic biology, chemical biology, nanobiotechnology, metabolic engineering, protein and glyco-engineering, tissue engineering, biocatalysis, biomimetics
3. Neural bases of behaviour
  • Biochemical
  • Pharmacology
  • Cell biology
1. protein engineering
2. drug screening
3. in vivo imaging
1. GPCRs
2. neuromodulators
3. neuropeptides
Markova Vendula
Charles University
CZwg2, wg41. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. 1. Mathematics (applications in science and industry)
  • Biochemical
  • Pharmacology
  • Biophysical
1. opioid receptors
2. TRPV1
3. arrestin
Dainese Enrico
University of Teramo
ITwg1, wg2, wg3, wg41. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Molecular mechanisms of signalling pathways
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Biochemical
  • Structural
  • Cell biology
1. Biochemical Metodologies for functional study of enzymes and receptors
2. SAXS, X-ray diffraction, molecular interactions by FRET and label free technologydocking analysis, homology model
3. In vitro imaging by confocal microscopy
1. Membrane proteins and lipids
2. GPCRs and lipoxygenase system
3. Cell signaling and trafficking
Unsal Serbulent
Karadeniz Technical University/Middle East Technical University
TRwg41. Bioinformatics
2. Machine learning
3. Proteomics
  • Computational
  • Computational
  • Computational
1. Machine Learning
2. Proteomics
3. Bioinformatics
1. Protein function prediction
2. Protein/Peptide/Antibody Selection/Design
3. Machine/Deep Learning
Novotny Jiri
Charles University, Faculty of Science
CZwg1, wg2, wg31. Cell signalling and signal transduction
2. Macromolecular complexes
3. Neural cell function, communication and signalling, neurotransmission
  • Cell biology
  • Pharmacology
  • Biochemical
1. cell signaling
2. radioligand binding
3. enzyme assays
1. GPCRs
2. G proteins
3. cytoprotection
Garcia Fernandez Maria Dolores
Institut de Biologie Structurale
FRwg2, wg41. Molecular mechanisms of signalling pathways
2. Applied bioengineering, synthetic biology, chemical biology, nanobiotechnology, metabolic engineering, protein and glyco-engineering, tissue engineering, biocatalysis, biomimetics
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Biophysical
  • Biochemical
YILMAZLAR Alize
Bogazici University
TRwg21. Molecular mechanisms of signalling pathways
2. Computational biology
3. Cell signalling and signal transduction
  • Computational
  • Computational
  • Computational
1. Neuroscience
2. In silico methods
3. Signal Transduction
Sahlholm Kristoffer
Umeå University
SEwg2, wg31. Molecular mechanisms of signalling pathways
2. Psychiatric disorders
3. Medicinal chemistry
  • Pharmacology
  • Biophysical
  • Behavioral
1. Live-cell signaling assays
2. Electrophysiology
3. models of antipsychotic efficacy
1. dopamine receptors
2. antipsychotics
3. structure-activity relationships
Gruber Christian
Medical University of Vienna
ATwg1, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Biochemical
  • Chemistry
1. drug discovery
2. signaling
3. natural product
1. peptide

Rajagopal Sudarshan
Duke University School of Medicine
wg21. Molecular mechanisms of signalling pathways
2. Biochemistry
3. Fundamental mechanisms underlying cardiovascular diseases
  • Biochemical
  • Pharmacology
  • Animal models


1. Biased Agonism
2. Chemokine
3. Arrestin
Wingler Laura
Duke University Medical Center
wg31. Biochemistry
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Applied bioengineering, synthetic biology, chemical biology, nanobiotechnology, metabolic engineering, protein and glyco-engineering, tissue engineering, biocatalysis, biomimetics
  • Biochemical
  • Pharmacology
  • Biophysical


1. Ligand pharmacology
2. Protein engineering
Melkes Barbora
Charles University
CZwg2, wg41. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Biochemical
  • Pharmacology
  • Biophysical


1. Opioid receptor
2. arrestin
3. TRPV1
Eiger Dylan
Duke University
wg1, wg2, wg3, wg41. Biochemistry
2. Cell signalling and signal transduction
3. 6. Cellular and Developmental Biology
  • Biochemical
  • Pharmacology
  • Cell biology
1. Bioluminescence Resonance Energy Transfer

1. G Protein Could Receptors
2. Signal Transduction
3. Biased Agonism
Weber Verena
Leibniz institute of food systems biology at TUM
DEwg1, wg3, wg4, wg51. Computational biology
2. Molecular mechanisms of signalling pathways
3. Scientific computing, simulation and modelling tools
  • Computational
  • Biochemical
  • Chemistry


1. Computer-aided drug design
2. molecular modeling
3. biochemistry
Bailey Chris
University of Bath
GBwg1, wg2, wg3, wg41. Neural cell function, communication and signalling, neurotransmission
2. Fundamental aspects of synthetic biology and chemical biology
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Animal models
  • Biophysical
1. Opioids
2. Addiction
3. Electrophysiology
1. GPCRs
2. Opioids
3. Biased agonists
Hoare Samuel
Pharmechanics LLC
wg2, wg3, wg41. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Cell biology
  • Computational


1. Kinetics
2. Spatiotemporal signaling
3. Systems pharmacology
Barreto Carlos
University of Coimbra
PTwg41. Scientific computing, simulation and modelling tools
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Bioinformatics
  • Computational
  • Computational
  • Computational
1. Structural Modeling
2. Molecular Dynamics
1. GPCR activation
2. GPCR signaling
3. Molecular Dynamics
Alenfelder Judith
University of Bonn
DEwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Pharmacology
  • Biochemical
  • Cell biology


1. GPCRs
2. G proteins
3. Signal Transduction
Caffrey Martin
Trinity College Dublin
IEwg1, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Biological chemistry
3. Biochemistry
  • Computational
  • Computational
  • Computational




Velazhahan Vaithish
MRC Laboratory of Molecular Biology
GBwg1, wg21. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Structural
  • Biophysical
  • Biochemical
1. Cryo-EM, NMR, X-ray Crystallography
2. SPR, SEC-MALS
3. Protein engineering
1. GPCR Structures
2. GPCR Dimers
3. Drug Development
Perera Suchi
University of Arizona
wg31. Physical chemistry of biological systems
2. Biological chemistry
3. 1. Mathematics (applications in science and industry)
  • Chemistry
  • Biophysical
  • Computational
1. Electronic Spectroscopy
2. Neutron scattering
3. X-ray scattering
1. Rhodopsin
2. Membrane proteins
3. Neutron scattering
Annibale Paolo
Max Delbrück Center for Molecular Medicine
DEwg41. Physics of biological systems
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biophysical
  • Biochemical
  • Pharmacology


1. Fluorescence Microscopy
2. Super-resolution imaging
3. Receptor Oligomerization
Gómez-Santacana Xavier
Institute for Advanced Chemistry of Catalonia (IQAC) - Spanish National Research Council (CSIC)
ESwg1, wg3, wg41. Biological chemistry
2. Medicinal chemistry
3. Photochemistry
  • Chemistry
  • Pharmacology
  • Biochemical
1. Medicinal Chemistry
2. Photopharmacology
3. Protein labelling
1. Medicinal Chemistry
2. Photopharmacology
3. Protein labelling
Abate Carmen
Università degli Studi di Bari
ITwg3, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational




Schihada Hannes
Karolinska Institutet
SEwg1, wg2, wg3, wg41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biophysical
  • Biophysical
  • Cell biology
1. BRET
2. biosensor
3. WNT signaling
1. orphan GPCRs
2. conformational biosensors
3. signal transduction
Pfersdorf Fabian
University of Copenhagen
DKwg1, wg21. Molecular mechanisms of signalling pathways
2. Biochemistry
3. Macromolecular complexes
  • Biochemical
  • Pharmacology
  • Structural
1. Purification
2. Signaling
3. Cryo-EM
1. Signaling
2. Structure
3. Pharmacology
van den bor jelle
Vrije universiteit amsterdam
NLwg1, wg2, wg31. Tissue organisation and morphogenesis
2. Stem cell biology
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Pharmacology
  • Biochemical




Kinsella Gemma
TU Dublin
IEwg31. Biological chemistry
2. Biocomputing and molecular computation
3. 12. Applied Life Sciences and Biotechnology
  • Computational
  • Biochemical
  • Chemistry


1. GPCRs

Jacobson Kenneth
National Institutes of Health
wg2, wg41. Medicinal chemistry
2. Cell signalling and signal transduction
3. Biochemistry
  • Chemistry
  • Computational
  • Pharmacology


1. adenosine receptors
2. P2Y receptors
3. P2X receptors
Mao Jiafei
Goethe University of Frankfurt am Main
DEwg11. Spectroscopic and spectrometric techniques
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Physics of biological systems
  • Structural
  • Biophysical
  • Chemistry
1. NMR
2. dynamics
3. ligand
1. structure
2. dynamics
3. methodology
Pacull Emelyne
University of Leipzig
DEwg11. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Protein synthesis, modification, turnover
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Biochemical
  • Structural
  • Biochemical
1. Cell-Free Synthesis
2. NMR
3. Protein purification
1. GPCRs
2. Structural Biology
3. Interactions
Zaccolo Manuela
University of Oxford
GBwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Fundamental mechanisms underlying cardiovascular diseases
3. Macromolecular complexes
  • Cell biology
  • Biochemical
  • Pharmacology
1. real-time imaging
2. protein biochemistry
1. cAMP
2. cGMP
3. cardiac myocyte
Paisdzior Sarah
Charité Universitaetsmedizin Berlin
DEwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Molecular aspects of endocrinology
  • Pharmacology
  • Cell biology
  • Cell biology
1. Signaling pathway Assays
2. Protein protein interaction
1. Melanocortin 4 receptor
2. Biased signaling
3. GPCR dimerization
Myers Benjamin
University of Utah School of Medicine
wg1, wg2, wg3, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational




Pfeil Eva Marie
Vrije universiteit Amsterdam
NLwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Cell differentiation, physiology and dynamics
  • Pharmacology
  • Pharmacology
  • Cell biology
1. G protein coupled receptors
2. Signal transduction mechanisms
3. In vitro cell culture
1. GPCR signaling
2. Calcium mobilization
3. Viral GPCRs
Nathanail Evangelia
University of Oxford
GBwg1, wg21. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Structural
  • Biochemical
  • Biophysical


1. Cell signaling
2. Structure-to-function
Janetzko John
Stanford University
wg1, wg31. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Spectroscopic and spectrometric techniques
3. Molecular architecture and structure
  • Biochemical
  • Structural
  • Biophysical
1. protein purification
2. protein structure
3. fluorescence spectroscopy
1. receptor recycling
2. arrestin domain proteins
3. receptor PTMs
Ripoll Léa
UCSF
wg1, wg2, wg31. Cell signalling and signal transduction
2. Organelle biology and trafficking
3. Neural cell function, communication and signalling, neurotransmission
  • Biophysical
  • Pharmacology
  • Cell biology
1. Fluorescence microscopy
2. GPCR signaling
3. Neuronal cultures
1. Membrane trafficking
2. GPCR signaling
3. Endosomal signaling
Menet Christel
Confo Therapeutics
BEwg1, wg2, wg3, wg4, wg51. Medicinal chemistry
2. Biochemistry
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Chemistry
  • Pharmacology
  • Clinical


1. Drug discovery
2. GPCR
3. biology
Auger Genevieve Marie
Universität Leipzig
DEwg2, wg3, wg41. Biochemistry
2. Neural cell function, communication and signalling, neurotransmission
3. Protein synthesis, modification, turnover
  • Computational
  • Computational
  • Computational


1. Biochemistry
2. Neurobiology
3. GPCRs
Kumar G Aditya
University of Michigan
wg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Lipid biology
  • Cell biology
  • Biochemical
  • Biophysical


1. Membrane
2. trafficking
3. GPCRs
Fischer Tobias
Leipzig University
DEwg11. Medicinal chemistry
2. Biological chemistry
3. 1. Mathematics (applications in science and industry)
  • Structural
  • Computational
  • Pharmacology


1. chemokines
2. modeling
3. peptides
Carvalho Sabrina
University of Cambridge
GBwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Computational




Nogueira Pedro
Campinas State University
wg1, wg2, wg3, wg41. 7. Physiology, Pathophysiology and Endocrinology
2. Metabolism, biological basis of metabolism-related disorders
3. Neural cell function, communication and signalling, neurotransmission
  • Animal models
  • Cell biology
  • Structural
1. Transgenic mouse model
2. Knockdown of gene expression
3. Protein content analysis
1. Metabolism
2. Neuroscience
3. Neurons and Astrocytes

COST

COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation.

COST Action CA18133

All cells face the vital challenge of sensing their environments and responding in appropriate ways. How are different signalling pathways activated and modulated in precise and reproducible ways? Filling this gap in knowledge is absolutely necessary to advance the next generation of pharmaceutical drugs.

COST Action

COST Action

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European Research Network on Signal Transduction