Member List

NameCountryWGERC code Techniques of expertise Connected keyword of expertise Research interests
Cordomí Arnau
Universitat Autònoma de Barcelona
ESWG1, WG31. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Structural
  • Chemistry
  • Biophysical
1. EPR and Fluorescence spectroscopy
2. GPCR and transducer purification
3. X-ray crystallography
1. dimers
2. signaling complexes
3. signal transduction
Dr. Daniel Hilger
Philipps-Universität Marburg
DEWG1, WG31. Molecular biophysics
2. Biochemistry
3. Structural biology and its methodologies
  • Biophysical
  • Biochemical
  • Structural

1. Electron paramagnetic resonance
2. Protein purification
3. Crystallography
1. Structure and dynamics of GPCRs and their complexes
2. Molecular basis of GPCR-mediated signaling
3. Drug development
Tikhonova, Irina
Queen's University Belfast
Website
GBWG1, WG3, WG51. Computational biology
2. Fundamental aspects of synthetic biology and chemical biology
3. Biochemistry
  • Computational
  • Biochemical
  • Pharmacology

1. MD simulations
2. Virtual screening
3. Structure-function
1. Allosteric sites
2. Dimerization
3. Drug design
Gmeiner, Peter
FAU
Website
DEWG31. Medicinal chemistry
2. Neurological disorders
3. Imaging for medical diagnosis
  • Chemistry
  • Pharmacology
  • Computational

1. Synthesis
2. In vitro assays
3. Molecular dynamics
1. GPCR ligands
2. Drug discovery
3. Structure based design
Kolb, Peter
Philipps-University Marburg
Website
DEWG3, WG51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Pharmacology

1. Docking
2. Homology modelling
1. Ligand selectivity
2. Prediction of affinity/efficacy/bias
3. Chemical universe
Rafael Franco
Universitat de Barcelona
ALWG1, WG21. Biological chemistry
2. Biochemistry
3. Neural cell function, communication and signalling, neurotransmission
  • Biochemical
  • Pharmacology
  • Biophysical
Di Pizio Antonella
Leibniz-Institute for Food Systems Biology at TUM
Website
DEwg1, wg3 1. Food sciences
2. Food sciences
3. Medicinal chemistry
  • Computational
  • Structural
  • Chemistry
Abatematteo Francesca Serena
University of Bari Aldo Moro
Website
ITwg3, wg41. Medicinal chemistry
2. Medicinal chemistry
3. Biological chemistry
  • Chemistry
  • Pharmacology
  • Computational
1. GPCRS
2. CB2
3.
Sztyler Agnieszka
Charité Medical University Berlin
Website
DEwg1, wg2, wg3 1. Biochemistry
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Biophysical
  • Structural
1. Fluorescence spectroscopy
1. GPCR
2. arrestin
3. signal transduction
Hauser, Alexander
University of Copenhagen
DKWG1, WG2, WG3, WG4, WG51. Bioinformatics
2. Systems biology
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Computational
  • Structural
  • Biophysical

1. Data science
2. Structure analysis
1. GPCRs
2. Pharmacogenomics
3. Structure Biology
Tobin, Andrew
University of Glasgow
GBWG21. Cell signalling and signal transduction
2. Neural cell function, communication and signalling, neurotransmission
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biochemical
  • Pharmacology
  • Cell biology

1. Neuroscience
2. Gut physiology
3. Respiratory disease
Ronken Ago
University of Tartu
Website
ALwg1, wg3, wg4 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Neural cell function, communication and signalling, neurotransmission
  • Pharmacology
  • Biophysical
  • Biochemical
1. Ligand binding properties
2. Superresolution microscopy for receptors
3. Fluorescent probes for receptors
1. kinetic mechanism of ligand binding
2. Regulation of ligand binding and signal transduction
3. Novel methods for receptor research
Shahraki Aida
Bogazici university
TRwg11. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Computational biology
  • Computational
  • Structural
  • Pharmacology
1. high-throughput virtual screening
2. peptide-based agonists
3. structural studies
Isbilir Ali
Max Delbrück Center for Molecular Medicine
DEwg1, wg2, wg3, wg4 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Molecular aspects of endocrinology
  • Pharmacology
  • Cell biology
  • Biophysical
1. Microscopy
2. Multiplexed
3. Biased
Mamyrbekov Alibek
University of Copenhagen
DKwg51. Bioinformatics
2. Bioinformatics
3. Scientific computing, simulation and modelling tools
  • Computational
  • Computational
  • Computational
Kliewer Andrea
University Hospital Jena
DEwg2, wg3, wg41. Neural bases of behaviour
2. Neural bases of behaviour
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Behavioral
  • Pharmacology
  • Animal models
1. pain/addiction behavior
2. opioids
3. genetic opioid receptor models
1.
2.
3.
Bock Andreas
Max-Delbrueck-Center for Molecular Medicine
Website
DEwg1, wg2, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Pharmacology
  • Biochemical
  • Biophysical
1. G protein-coupled receptors
2. cyclic nucleotides
3. FRET
1. Compartmentalization
2. G protein-coupled receptors
3. Biomolecular condensates
Chevigné Andy
Luxembourg Institute of Health
ALwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Cell biology
  • Pharmacology
  • Structural
1. GPCR
2. Chemokine
3. signaling
ALMERICO ANNA MARIA
University of Palermo
Website
ITwg1, wg3, wg4 1. Method development in chemistry
2. Method development in chemistry
3. Bioinformatics
  • Computational
  • Chemistry
  • Biochemical
1. molecular modelling
2. synthesis and drug design
3. mechanism of action of new drugs
1. drug design and synthesis
2. QSAR and SAR analysis
3. antitumor/antivirus/antimicrobial agents
Kan Beki
Acibadem Mehmet Ali Aydinlar University
Website
TRwg1, wg2 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Cell death (including senescence) and autophagy
  • Biochemical
  • Cell biology
  • Biophysical
1. Signal transduction cascades, second messengers
2. protein structure and function
1. GPCRs and G proteins
2. Neurodegeneration
3. Autophagy
Haran Tali
Technion
ILwg11. Molecular architecture and structure
2. Molecular architecture and structure
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Biophysical
  • Structural
  • Computational
1. Affinity and stability measurements
2. Flexibility measurements
3. Analysis of NGS data
1. Protein-DNA interactions
2. P53 functionality
3. Gene regulation
Bondar Alexey
Center for Nanobiology and Structural Biology
CZwg1, wg2, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Biophysical
  • Cell biology
  • Biochemical
1. clathrin
2. single-molecule imaging
3. preassembly
Xu Bo
uppsala university
Website
SEwg1, wg2, wg3, wg41. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. 12. Applied Life Sciences and Biotechnology
  • Pharmacology
  • Cell biology
  • Biochemical
1. in vitro pharmacology
2. cell culture and transfection
3. in situ proximity ligation assay
1. signalling pathway
2. GPCR
3. biosensor development
Brkljačić Jelena
Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade
Website
RSwg2, wg31. Molecular aspects of endocrinology
2. Molecular aspects of endocrinology
3. Metabolism, biological basis of metabolism-related disorders
  • Biochemical
  • Biochemical
  • Animal models
1. Glucocorticoid receptor
2. Redox signalling
3. Metabolic disorders
Rosano Camillo
IRCCS Policlinico San Martino - Genova (I)
ALwg1, wg2, wg3, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Scientific computing, simulation and modelling tools
  • Structural
  • Computational
  • Biochemical
1. Crystallography
2. Molecular Simulations
1. Oncology
2. Drug Design
3.
Cevheroglu Orkun
Ankara University
Website
TRwg1, wg2, wg3, wg41. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Cell signalling and signal transduction
  • Biochemical
  • Cell biology
  • Biophysical
1. BRET
2. FRET
3. BiFC
de Graaf Chris
Sosei Heptares
Website
GBwg1, wg2, wg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Computational
  • Chemistry
  • Structural
1. Cheminformatics
2. Computational Medicinal Chemistry
3. Structure-Based Drug Discovery
1. G Protein-Coupled Receptors
2. Computer-Aided Drug Design
3. Structural Bioinformatics
Munk Christian
Copenhagen University
Website
DKwg51. Bioinformatics
2. Bioinformatics
3. Machine learning
  • Computational
  • Computational
  • Computational
1. GPCRs
2. Biased signalling
3. Structure analysis
MOREAU Christophe
CNRS
FRwg41. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds)
2. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds)
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Biophysical
  • Biochemical
  • Biochemical
1. electrophysiology
2. protein engineering
3. Ion channel-coupled receptor
1. electrical bionsensors
2. GPCRs
3. ion channel reporter
Bonnesen Cecilie
University of Copenhagen
DKwg1, wg2, wg3, wg4 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3.
  • Structural
  • Structural
  • Biochemical
Maccallini Cristina
University G. d'Annunzio of Chieti-Pescara
ITwg3, wg4 1. Medicinal chemistry
2. Medicinal chemistry
3. Analytical chemistry
  • Chemistry
  • Biochemical
  • Pharmacology
1. Synthesis
2. enzyme inhibition
3. nitric oxide
1. Synthesis
2. small molecules
3. nitric oxide
Goudet Cyril
Institut de Genomique Fonctionnelle
Website
FRwg11. Neural cell function, communication and signalling, neurotransmission
2. Neural cell function, communication and signalling, neurotransmission
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Pharmacology
  • Animal models
1. Neuropharmacology
2. Photopharmacology
3. Chronic pain
1. GPCR
2. Pain
3. Neuromodulation
Calebiro Davide
University of Birmingham
Website
GBwg1, wg2, wg3, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Molecular aspects of endocrinology
  • Biophysical
  • Pharmacology
  • Computational
1. single-molecule microscopy
2. FRET
3. quantitative biology
1. GPCRs
2. cAMP
3. signal compartmentalization
van der Es Daan
Leiden University
falsewg31. Organic chemistry
2. Organic chemistry
3. Biological chemistry
  • Chemistry
  • Chemistry
  • Chemistry
1. Organic Synthesis
2. Chemical Biology
3. Molecular Probes
Abboud Dayana
University of liege
ALwg1, wg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Metabolism, biological basis of metabolism-related disorders
  • Pharmacology
  • Animal models
  • Biochemical
1. GPCR
2. Orphan GPCR
3. Signal transduction
Hilger Daniel
Philipps University of Marburg
DEwg1, wg3, wg4 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Biophysical
  • Biochemical
  • Structural
1. Electron paramagnetic resonance
2. protein purification
3. Crystallography
1. GPCRs
2. Structural dynamics
3. molecular basis of GPCR signaling
Kirovski Danijela
University of Belgrade
Website
RSwg31. Molecular aspects of endocrinology
2. Molecular aspects of endocrinology
3. Metabolomics
  • Animal models
  • Biochemical
  • Clinical
1. domestic animals
2. PCR technique
3. Loading tests
1. Domestic animals
2. cell signaling
3. metabolism
Daniel Legler
Biotechnology Institute Thurgau at the University of Konstanz
CHWG1, WG2, WG31. Mathematics
2. Mathematics
3. Mathematics
  • Computational
  • Computational
  • Computational

1. GPCR signaling
2. Chemokine
3. Cell migration
Ler Daria
Eurofarm Centar Polyclinic
Website
falsewg1, wg2, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Proteomics
  • Clinical
  • Biochemical
  • Cell biology
1. molecular biomarkers
2. cancer biology
3.
KELES Didem
Izmir University of Economics
TRwg2, wg3 1. Fundamental mechanisms underlying cancer
2. Fundamental mechanisms underlying cancer
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Biochemical
  • Cell biology
1. Zymography
2. Western blotting
3. 3D spheroid
1. Cancer metastasis and extracellular matrix
2. Drug repurposing
3. Voltage gated sodium channels and signaling
Djordjevic Ana
Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade
Website
RSwg2, wg31. Molecular aspects of endocrinology
2. Molecular aspects of endocrinology
3. Molecular mechanisms of signalling pathways
  • Animal models
  • Biochemical
  • Cell biology
1.
2.
3.
DOGAN SONER
Yeditepe University, School of Medicine
Website
TRwg21. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Epigenetics and gene regulation
  • Animal models
  • Cell biology
  • Biochemical
1. cancer mouse model
2. micro RNA array by afymetrix
3. Pyrosquencing
1. Epigenetics
2. Ageing
3. Calorie restriction
Vojnović Milutinović Danijela
Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade
Website
RSwg2, wg31. Molecular aspects of endocrinology
2. Molecular aspects of endocrinology
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Animal models
  • Cell biology
1. protein expression
2. metabolic disorders
3. histological analysis
1. PCOS
2. glucocorticoids
3. insulin signaling pathway
Vavers Edijs
Latvian Institute of Organic Synthesis
Website
LVwg31. Neurological disorders
2. Neurological disorders
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Animal models
  • Behavioral
1. Drug discovery, Molecular mechanisms, Screening
2. Stroke, Traumatic brain injury, Dementia, Epilepsy
3. Animal behaviour, Learning and memory, Depression, Anxiety, Pain perception, Neurological severity assessment
1. Sigma-1 chaperone protein
2. Epileptogenesis
3. Novel compounds
Feeney Emma
University College Dublin
IEwg21. Sensation and perception
2. Sensation and perception
3. Epidemiology and public health
  • Behavioral
  • Structural
  • Clinical
1. Sensory evaluation
2. taste perception
3. psychophysics
1. taste perception
2. sensory evaluation
3. food structure
Lacivita Enza
University of Bary
ITwg31. Medicinal chemistry
2. Medicinal chemistry
3. Neuronal development, plasticity and regeneration
  • Chemistry
  • Pharmacology
  • Computational
1. GPCRs
2. neuroinflammation
3. biased agonism
Ghosh Eshan
Copenhagen University
Website
DKwg1, wg3, wg4, wg5 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Fundamental aspects of synthetic biology and chemical biology
  • Biochemical
  • Cell biology
  • Structural
1. Protein chemistry
2. Co-immunoprecipitation
3. Cryo-EM and Crystallography
1. GPCR Structural Biology
2. Macromolecular Assembly
3. Protein Evolution
Moreno Estefanía
University of Barcelona
Website
ESwg1, wg21. Biochemistry
2. Biochemistry
3. Neural cell function, communication and signalling, neurotransmission
  • Biochemical
  • Biochemical
  • Pharmacology
1. Biophysical and immunological techniques
2. Functional techniques
3. Pharmacological techniques
1. The biochemistry, physiology and pharmacology of G-protein coupled receptors
2. Heteromerization of G Protein Coupled Receptors
3. Neurodegenerative and neurological diseases
Tripp Emma
University of Birmingham
Website
GBwg1, wg2, wg3, wg4, wg51. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Metabolism, biological basis of metabolism-related disorders
  • Pharmacology
  • Cell biology
  • Computational
1. Microscopy
2. BRET
1. GPCRs
2. Cell signalling
3. Adipocytes
Finn Olav Levy
University of Oslo
Website
NOWG1, WG21. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Fundamental mechanisms underlying cardiovascular diseases
  • Pharmacology
  • Animal models
  • Biophysical

1. PDE assays
2. HFpEF
3. FRET
1. Serotonin receptors
2. Cyclic nucleotides
3. Phosphodiesterases
Fierro Fabrizio
Hebrew University
ILwg1, wg31. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Systems neuroscience and computational neuroscience
  • Computational
  • Structural
  • Biochemical
1. Homology modelling
2. Docking
3. Molecular Dynamics
1. GPCR
2. bitter taste receptors
3.
Ballante Flavio
Uppsala University
Website
SEwg3, wg4, wg5 1. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Computational
  • Computational
1. Structure-based drug design
2. Ligand-based drug design
3. Quantitative modelling
1. Drug design
2. Computational chemistry
3. Medicinal chemistry
Wilhelm Florian
ETH Zürich
CHwg1, wg2, wg41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Physics of biological systems
  • Biophysical
  • Pharmacology
  • Pharmacology
1. Atomic Force Microscopy
2. Ligand Binding
3. cellular FRET-based kinetic assays
1. Arrestin
2. GPCR Phosphorylation
3. GPCR Signaling
Mayor Jr Federico
Universidad Autónoma Madrid
ESwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Cell biology
  • Animal models
  • Biochemical
1.
2.
3.
Acher Francine
University Paris Descartes
Website
FRwg31. Medicinal chemistry
2. Medicinal chemistry
3. Neurological disorders
  • Chemistry
  • Pharmacology
  • Structural
1. medicinal chemistry
2. neuropharmacology
3. molecular modeling
1. glutamate
2. GPCRs
3. transporters
van Westen Gerard
Leiden University (LACDR)
Website
ALwg3, wg4 1. Artificial intelligence, intelligent systems, multi agent systems
2. Artificial intelligence, intelligent systems, multi agent systems
3. Medicinal chemistry
  • Computational
  • Computational
  • Computational
1. machine-learning
2. structure-based
3. proteochemometrics
1. neural-networks
2. GPCRs
3. oncology
Wolber Gerhard
Freie Universitaet Berlin
Website
DEwg3, wg5 1. Medicinal chemistry
2. Medicinal chemistry
3. Artificial intelligence, intelligent systems, multi agent systems
  • Computational
  • Structural
  • Pharmacology
1. Mechanistic understanding of efficacy & bias
2. Tailored ligand design & optimization
3. Virtual screening techniques using molecular dynamics simulations
Morra Giulia
Consiglio Nazionale delle Ricerche
ITwg1, wg3 1. Biocomputing and molecular computation
2. Biocomputing and molecular computation
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Computational
  • Computational
  • Computational
1. Modeling of allosteric phenomena
2. protein dynamics
3. Drug discovery
Innamorati Giulio
University of Verona
ITwg1, wg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Biochemical
  • Pharmacology
Mangiatordi Giuseppe Felice
National Research Council
ITwg1, wg2, wg3, wg4, wg51. Computational biology
2. Computational biology
3. Theoretical and computational chemistry
  • Computational
  • Biophysical
  • Structural
1. Drug Design, Structure Prediction
2. QM/MM, ADMET
3. Molecular Dynamic Simulation
1. Docking simulations
2. MD simulations
3. Cannabinoid receptors
Tatar Gizem
Karadeniz Technical University
TRwg21. Bioinformatics
2. Bioinformatics
3. Computational biology
  • Computational
  • Chemistry
  • Biophysical
1. Computational Drug Design
2. Computational Biology and Bioinformatics
3. Molecular Biology and Genetics
Krause Gerd
Leibniz-Forschungsinstitut für molekulare Pharmakologie (FMP)
Website
DEwg3, wg5 1. Molecular architecture and structure
2. Molecular architecture and structure
3. Molecular aspects of endocrinology
  • Pharmacology
  • Structural
  • Computational
1. molecular
2. bioinformatics
3. protein design
1. membrane proteins
2. structure-function relationshipss
3. pharmacological intervention
Ladds Graham
Cambridge
GBwg1, wg2, wg3, wg41. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Computational
  • Biochemical
1. GPCRs
2. Modelling
3. Pharmacology
Guccione Salvatore
Catania
Website
ALwg31. Medicinal chemistry
2. Medicinal chemistry
3. Organic chemistry
  • Computational
  • Computational
  • Computational
1. Drug Design
2. Drug synthesis
3.
Lebon Guillaume
Montpellier Universsity
FRwg1, wg2, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Macromolecular complexes
  • Biochemical
  • Structural
  • Pharmacology
1. Membrane protein
2. X-ray, cryoEM
3. GPCRs
1. GPCRs signal transduction
2. Structural Biology
3. pharmacology
Çubukçuoğlu Deniz Günseli
Ankara University
TRwg1, wg21. Stem cell biology
2. Stem cell biology
3. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology
  • Cell biology
  • Biophysical
  • Computational
1. cell culture
2. pcr, wb
3. microarray
1. heart failure
2. heart rhythm
3. molecular signaling of cardiomyocytes
Dr. Henry Vischer
Vrije Universiteit Amsterdam
NLWG1, WG3, WG3, WG41. Cell signalling and signal transduction
2. Biological chemistry
3. Medicinal chemistry
  • Cell biology
  • Pharmacology
  • Computational

Bräuner-Osborne Hans
University of Copenhagen
Website
DKwg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Computational
  • Computational
1. GPCR
2. molecular pharmacology
3. mechanism-of-action
Cabadak Hulya
Marmara University School of Medicine
TRwg2, wg31. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Cell death (including senescence) and autophagy
  • Cell biology
  • Pharmacology
  • Biochemical
1. Cell culture and western blotting
2. Signalling pathway detection with ELİSA (NO,cAMP,Ca etc.)
3. Nücleic acid isolation (DNA,RNA) ,Real time PCR,
1. GPCR and G proteins, Cell growth and Death Pathway
2. Drug effects on GPCR and related signalling pathways
3.
Biebermann Heike
Charité Universitätsmedizin Berlin
Website
ALwg2, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Biochemical
1. signalling modulation
2. biased signaling
3. pathway selected ligands
Danielson Helena
Uppsala University
ALwg1, wg3, wg41. Biochemistry
2. Biochemistry
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biochemical
  • Biophysical
  • Structural
1. Molecular interactions
2. Molecular interactions
1. Molecular interactions
2. Drug discovery
3. Method development
CASTEL Hélène
University Rouen Normandie
Website
FRwg1, wg2, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Neural cell function, communication and signalling, neurotransmission
  • Cell biology
  • Animal models
  • Behavioral
1. Invasion
2. Transparization iDISCO
3. cell behavior
1. Neuro-oncology
2. animal behavior
3. Cancer
Daver Henrik
University of Copenhagen
DKwg1, wg3 1. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational
1. MD simulations
2. DFT calculations
1. Protein-protein interactions
2. Computational drug design
Gutierrez de Teran Hugo
Uppsala University
Website
ALwg3, wg4, wg5 1. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Biocomputing and molecular computation
  • Computational
  • Structural
  • Chemistry
1. Molecular Dynamics
2. Structural Bioinformatics
3. Free Energy Calculations
1. GPCR
2. Free Energy
3. adenosine receptors
Erol Ismail
Gebze Technical University
TRwg1, wg4, wg5 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Biocomputing and molecular computation
  • Computational
  • Structural
  • Biophysical
1. GPCRs
2. Molecular simulations
3. oligomerization
Iatrou Kostas
National Centre for Scientific Research "Demokritos"
Website
GRwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Sensation and perception
  • Biochemical
  • Pharmacology
  • Behavioral
1. cell-based screening systems
2. ligand binding assays
3. insect attraction-repellence assays
1. insects
2. odorant receptors
3. olfactory function modulators
Simon Icaro Ariel
University of Copenhagen
DKwg1, wg2, wg3, wg4, wg51. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Biocomputing and molecular computation
  • Computational
  • Chemistry
  • Structural
1. Molecular dynamics
2. Structure-activity relationships
3. Homology modeling
1. molecular modeling
2. gpcr
3. biased signalling
IJzerman Ad
Leiden University
falsewg31. Medicinal chemistry
2. Medicinal chemistry
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Chemistry
  • Computational
1. GPCR, adenosine receptors
2. new chemical entities, chemical probes
3. homology modeling, (Q)SAR
1. target binding kinetics
2. allosteric modulation
3. GPCR structure
Sylte Ingebrigt
UiT The Arctic University of Norway
Website
NOwg1, wg3 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational
1. Virtual ligand screening
2. Molecular dynamics simulations
3. Homology modeling and in silico mutations
1. G-protein coupled receptors
2. Transporter proteins
3. Molecular mechanisms
Moreira Irina
Coimbra University
Website
PTwg1, wg4, wg5 1. Computational biology
2. Computational biology
3. Machine learning
  • Computational
  • Chemistry
  • Structural
1. Deep-learning
2. Drug discovery
3. GPCR function-structure
Georgoussi Zafiroula-Iro
National Centre for Sceintific Research "Demokritos"
Website
GRwg1, wg2, wg3, wg4, wg51. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Neural cell function, communication and signalling, neurotransmission
  • Cell biology
  • Pharmacology
  • Biochemical
1. GPCR function
2. Bias signaling
3. GPCR pharmacology
1. Opioid receptors
2. G and RGS proteins and effectors
3. G protein signaling-dependent behaviors
Hanson Julien
University of Liège
Website
BEwg1, wg2, wg3, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Pharmacology
  • Cell biology
1. orphan GPCR
2. Endocrinology
3. Metabolism
Grimes Jak
University of Birmingham
GBwg1, wg2, wg41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Physics of biological systems
  • Biophysical
  • Pharmacology
  • Cell biology
1. Single-Molecule Microscopy
2. GPCR
3. Cell-based assays
1. single-particle tracking of GPCRs
2. Receptor Pharmacology
3. Computational analysis of receptor dynamics
golebiowski jerome
U cote d azur
Website
FRwg31. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Pharmacology
1. smell
2. taste
García Nafría Javier
Institute of Biocomputation and Physics of Complex Systems, University of Zaragoza
ESwg11. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Macromolecular complexes
  • Structural
  • Biophysical
  • Biochemical
1. membrane protein complexes
2. structural biology
3. cryo-EM
Mathiesen Jesper
Zealand Pharma
DKwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Cell signalling and signal transduction
  • Pharmacology
  • Biochemical
  • Structural
Tiemann Johanna
University Leipzig
DEwg1, wg2, wg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Computer graphics, computer vision, multi media
  • Computational
  • Structural
  • Pharmacology
1. MD
2. Modeling
3. Design
1. GPCR dynamics
2. Dynamic network
3. Knowledge collection
Blanco Canosa Juan Bautista
Institute for Advanced Chemistry of Catalonia
Website
ESwg3, wg41. Biological chemistry
2. Biological chemistry
3. Organic chemistry
  • Chemistry
  • Chemistry
  • Biophysical
1. Sonic Hedgehog
2. protein synthesis
3. posttranslation modifications
Villà-Freixa Jordi
Universitat Internacional de Catalunya
Website
ALwg1, wg4 1. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions
2. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions
3. Physical chemistry
  • Computational
  • Structural
  • Biochemical
1. Computational Chemistry
2. Modelling
3. Enzyme catalysis
1. Enzyme catalysis
2. Molecular Dynamics
3. Protein-Protein Interactions
Voß Jan Hendrik
University of Bonn
DEwg1, wg3 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3.
  • Pharmacology
  • Biochemical
  • Computational
1. Radioligand-binding experiments
2. Site-directed mutagenesis
3. Molecular dynamics
1. Binding kinetics
2. Structure-function relationship
3.
Springael Jean-Yves
Université Libre de Bruxelles
Website
ALwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. 9. Immunity and Infection
  • Pharmacology
  • Biochemical
  • Biophysical
1. Binding (Caturation/Competition/Association-Dissociation kinetics)
2. Signaling (G prot/Arrestin/cAMP/Ca/MAPK/Endocytosis/Chemotaxis)
3. BRET
1. GPCR
2. chemokine
3. BRET
Harpsøe Kasper
University of Copenhagen
Website
DKwg3, wg5 1. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Bioinformatics
  • Computational
  • Computational
  • Computational
1. Ligand binding mode prediction
2. Molecular dynamics simulation
3. In silico prediction of protein mutagenesis
1. Biased agonists
2. Inhibitors of G protein mediated signaling
3. Analysis of ligand binding determinants
Nemec Katarina
Max Delbrück Center for Molecular Medicine
Website
DEwg1, wg2, wg3, wg4, wg51. Biological chemistry
2. Biological chemistry
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Cell biology
  • Biochemical
1. GPCR
2. RAMP
3. HTS
Tate, Chris
MRC Laboratory of Molecular Biology
Website
GBWG1, WG41. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Macromolecular complexes
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Structural
  • Biophysical
  • Biochemical

1. cryo-EM & X-ray crystallography
2. ITC & SPR
3. Expression & purification
1. GPCR complexes
2. Structure
3. Dynamics
Vachkova Ekaterina
Trakia University
Website
BGwg1, wg2 1. Stem cell biology
2. Stem cell biology
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Animal models
  • Biochemical
1. isolation stem cells
2. aplication of stem cells and their products
3. nutritional factors
1. stem cells
2. adipose tissue
3. regenerative medicine
Jonas Kim
King’s College London
GBwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Molecular aspects of endocrinology
  • Cell biology
  • Pharmacology
  • Biochemical
1. Single molecule imaging
2. GPCR
3. GPCR
1. GPCRs
2. Endocrinology
3. Cellular signalling
Krasel, Cornelius
Philipps-University Marburg
Website
DEWG11. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Mathematics (applications in science and industry)
  • Pharmacology
  • Biochemical
  • Cell biology

Nativi, Cristina
University of Florence
Website
ITWG31. Organic chemistry
2. Glycomics/Lipidomics
3. Glycobiology
  • Chemistry
  • Computational
  • Computational

1. In vitro tests
2. Animal model
3. Glycobiology
Sotelo, Eddy
University of Santiago de Compostela
Website
ESWG2, WG3, WG41. Medicinal chemistry
2. Biological chemistry
3. Fundamental aspects of synthetic biology and chemical biology
  • Chemistry
  • Chemistry
  • Pharmacology

1. Synthesis ligands
2. conjugation strategies
3. GPCRs
1. Optimization of new ligands
2. New conjugation strategies
3. Biasedligands, allosteric modulators and bitopic ligands
Osborne, Greg
Heptares Therapeutics
Website
GBWG1, WG2, WG3, WG41. Mathematics (applications in science and industry)
2. Mathematics (applications in science and industry)
3. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational

Alves, Isabel
U. of Bordeaux
PTWG1, WG21. Molecular biophysics
2. Biological chemistry
3. Psychiatric disorders
  • Biophysical/plasmon waveguide resonance
  • Biochemical/signal transduction cascades
  • Biophysical/Calorimetry

1. plasmon waveguide resonance
2. signal transduction cascades
3. Calorimetry
1. lipid impact in signal transduction
2. ligand-receptor interaactions
3. cryo EM, sensor technologies, in cell FRET
Liebscher, Ines
Leipzig University
DEWG1, WG21. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Biochemical
  • Pharmacology
  • Animal models

1. Adhesion GPCR
2. Mechano-activation
3. Deorphanization
Dr. Julie Sanchez
University of Nottingham
UKWG1, WG2, WG31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics
  • Pharmacology
  • Cell biology
  • Pharmacology

1. BRET - FRET
2. Fluorescent biosensors
3. Ligand characterisation
1. GPCR signalling and modulation
2. GPCRs involved in CNS disorders and pain
3. Chemokine receptors
Nikolic Katarina
University of Belgrade, Faculty of Pharmacy
Website
RSwg3, wg51. Medicinal chemistry
2. Medicinal chemistry
3. Systems neuroscience and computational neuroscience
  • Computational
  • Chemistry
  • Biochemical
1. Computer-Aided Drug Design
2. Molecular Dynamic Simulations
3. Virtual Screening
1. serotonin receptors antagonists
2. alpha2/imidazoline receptor agonists
3. kinase inhibitors
Kosloff Mickey
University of Haifa
Website
ILwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Computational
  • Biochemical
  • Structural
1. Structural bioinformatics

1. G proteins, GAPs, effectors
2. Interaction specificity
3. Signaling complexes
Kostenis Evi
University of Bonn
DEwg1, wg2, wg3, wg41. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Biochemical
1. signal transduction
2. signal transduction
3. signal transduction
1. GPCR
2. G Protein
3. signal transduction
Khakurel Krishna
Institute of Physics
CZwg3, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Scientific computing, simulation and modelling tools
  • Structural
  • Computational
  • Biophysical
1. MicroED, CryoEM
2. Data Analysis, Computational tools Development
3. Spectroscopy and microscopy
1.
2.
3.
Chung Ka Young
Sungkyunkwan University
falsewg11. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Cell signalling and signal transduction
  • Structural
  • Biochemical
  • Cell biology
1. GPCR signaling
2. Protein conformation
Laasfeld Tõnis
University of Tartu
Website
EEwg4, wg5 1. Method development in chemistry
2. Method development in chemistry
3. Systems biology
  • Pharmacology
  • Pharmacology
  • Computational
1. GPCR
2. Ligand binding models
3. Bioimage analysis
1. deep learning for bioimage analysis
2. superresolution microscopy
3. kinetic models of ligand binding
Lamghari Meriem
Institute Of Biomedical Engineering/Institute for Research and Innovation in Health Sciences
Website
PTwg21. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 7. Physiology, Pathophysiology and Endocrinology
  • Cell biology
  • Animal models
  • Cell biology
1. Microfluidic for cells communication studies
2. 3D cell culture models
3. Bioengineering
Barki-Harrington Liza
University of Haifa
ILwg1, wg2, wg3 1. Protein synthesis, modification, turnover
2. Protein synthesis, modification, turnover
3. Biochemistry
  • Biochemical
  • Cell biology
  • Pharmacology
1. GPCR
2. cyclooxygenase
3. protease
Borrega Leire
Universidad del País Vasco/Euskal Herriko Unibertsitatea
Website
ALwg1, wg2, wg3, wg4, wg51. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Cell signalling and signal transduction
  • Pharmacology
  • Computational
  • Computational
1. Selective functionality
2. Kinetics of ligand
3. membrane cholesterol
Stoddart Leigh
University of Nottingham
GBwg3, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Biophysical
  • Pharmacology
1. Resonance Energy Transfer (BRET, FRET)
2. Fluorescence correlation spectroscopy
3. Binding kinetics
1. Binding kinetics
2. Membrane organisation of receptors
3. GPCR fluorescent ligands
pardo leonardo
universidad autonoma de barcelona
Website
ESwg3, wg4 1. Computational biology
2. Computational biology
3. Bioinformatics
  • Computational
  • Computational
  • Computational
1. molecular dynamics
2. virtual screening
1. oligomerization
2. drug design
Nygaard Mads Mørup
University of Copenhagen
DKwg31. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Biochemistry
  • Structural
  • Computational
  • Computational
1. Peptides
2. Simulations
Leopoldo Marcello
Università degli Studi di Bari Aldo Moro
ALwg3, wg4 1. Medicinal chemistry
2. Medicinal chemistry
3. Fundamental aspects of synthetic biology and chemical biology
  • Chemistry
  • Pharmacology
  • Animal models
1. Allosteric modulators
2. Orphan Receptors
3. Biased agonists
Tahk Maris-Johanna
University of Tartu
Website
EEwg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Biochemistry
  • Biochemical
  • Biochemical
  • Biochemical
1. Genetically encoded FRET-based biosensors assays for cAMP and apoptosis
2. Fluorescence anisotropy
3. Making and using baculoviruses and BacMam systems
1. Cell signaling pathways
2. Ligand-receptor interactions
3. Biosensors
martinez Karen
University of Copenhagen
DKwg1, wg2, wg3, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Surface science and nanostructures
  • Biophysical
  • Computational
  • Computational
1. fluorescence microscopy

Floor Martin
University of Vic
Website
ESwg1, wg3, wg4 1. Biocomputing and molecular computation
2. Biocomputing and molecular computation
3. Fundamental aspects of synthetic biology and chemical biology
  • Biochemical
  • Biophysical
  • Computational
1. Protein design
2. Enzyme design
3. Structural bioinformatics
Szpakowska Martyna
Luxembourg Institute of Health
LUwg1, wg2, wg3, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Cell biology
  • Pharmacology
  • Structural
1. GPCR
2. Chemokines
Niv Masha
The Hebrew University of Jerusalem, Israel
Website
ILwg3, wg5 1. Biochemistry
2. Biochemistry
3. Food sciences
  • Computational
  • Behavioral
  • Chemistry
1. homology modeling
2. sensory studies
3. chemoinformatics
1. GPCRs
2. taste receptors
3. drug discovery
Vrecl Fazarinc Milka
University of Ljubljana, Veterinary Faculty
Website
SIwg11. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Morphology and functional imaging of cells and tissues
  • Cell biology
  • Biophysical
  • Cell biology
1. confocal microscopy
2. BRET
3. fluorometric measurements
1. GPCRs
2. protein-protein interactions
3. ntracellular signaling
STOEBER MIRIAM
University of Geneva
Website
CHwg1, wg2, wg3, wg4, wg5 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Neural cell function, communication and signalling, neurotransmission
  • Cell biology
  • Biochemical
  • Pharmacology
1. Microscopy1. Subcellular Location
2. Signal Transduction
3. Neuropharmacology
Misicka-Kesik Alekssandra
University of Warsaw
PLwg11. Medicinal chemistry
2. Medicinal chemistry
3. Analytical chemistry
  • Chemistry
  • Pharmacology
  • Computational
1. HPLC MS
2. pain study
1. bifuncional peptidomimetics
2. MOR, DOR
3. melanocortin MC4 receptors
Wozniak Monika
University in Liege
BEwg2, wg3, wg4 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. 6. Cellular and Developmental Biology
  • Pharmacology
  • Biochemical
  • Cell biology
Grigorova Natalia
Trakia University
Website
BGwg1, wg21. Metabolism, biological basis of metabolism-related disorders
2. Metabolism, biological basis of metabolism-related disorders
3. Food sciences
  • Animal models
  • Cell biology
  • Biochemical
1. obesity-related disorders
2. bioactive food additives
3. signal transduction
Vardjan Nina
University of Ljubljana, Faculty of Medicine
SIwg21. 8. Neuroscience and Neural Disorders
2. 8. Neuroscience and Neural Disorders
3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
  • Cell biology
  • Biochemical
  • Animal models
1. Fluorescence Microscopy, Live cell imaging, IHC, ICC
2. WB, Biochemical assays
3. Drosophila, Rodents (mouse, rat) - animal models of neurological disorders
1. Astroglia physiology
2. GPCR-mediated cell signalling, metabolism, exocytosis
3. Neuorodegeneration
Saraiva Nuno
Universidade Lusófona
Website
PTwg1, wg2, wg4 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Cytoskeleton and cell behaviour
  • Cell biology
  • Cell biology
  • Cell biology
1. ROS and Ca2+ signalling
2. Cell motility
3. Cancer progression
Velickovic Natasa
Institute for biological research Sinisa Stankovic
Website
RSwg2, wg31. Metabolism, biological basis of metabolism-related disorders
2. Metabolism, biological basis of metabolism-related disorders
3. Non-communicable diseases
  • Biochemical
  • Animal models
  • Biochemical
1. protein expression
2. animal model of metabolic disease
3. hormone analysis
1. diabetes
2. hepatic metabolism
3. endocrinology
Sensoy Ozge
Istanbul Medipol University
TRwg1, wg2, wg3 1. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Cell signalling and signal transduction
  • Computational
  • Biophysical
  • Structural
1. Molecular dynamis simulation
2. Computational biophysics
3. Computational structural biology
1. GPCR biased signaling
2. Neurological disorders
3. Cancer
Pascale Crépieux
CNRS
Website
FRwg1, wg21. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Molecular aspects of endocrinology
  • Cell biology
  • Pharmacology
  • Computational
1. GPCR
2. VHH
3. Signaling Network
1. GPCR
2. signaling networks
3. mRNA translation
Scheerer Patrick
Charité - Universitätsmedizin Berlin
Website
DEwg1, wg2, wg3, wg4, wg51. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Structural
  • Biophysical
  • Biochemical
1. Protein X-ray Crystallography
2. Time-resolved Methods
3. Signal Transduction
1. Structural biology and Dynamics on GPCRs
2. Activation mechanisms of GPCRs
3. GPCR Signal Transduction
Morales Paula
Spanish Research Council
ESwg3, wg51. Medicinal chemistry
2. Medicinal chemistry
3. Theoretical and computational chemistry
  • Chemistry
  • Computational
  • Structural
1. Synthetic Medicinal Chemistry
2. Drug discovery and development
3. Endocannabinoid system
Jockers Ralf
University of Paris
Website
ALwg2, wg3 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Cell signalling and signal transduction
  • Biochemical
  • Pharmacology
  • Animal models
1. GPCR
2. Melatonin
3. Leptin
Reiner David
Heinrich-Heine-University
Website
DEwg1, wg3, wg4, wg51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Biological chemistry
  • Pharmacology
  • Biochemical
  • Chemistry
1. Analytical GPCR Pharmacology
2. Biochemistry of Proteins
3. Spectroscopic Analytics
1. Ligand-Receptor Binding Kinetics
2. Biased Signalling
3. Allosterism and GPCR Oligomerization
Lane Rob
University of Nottingham
Website
GBwg1, wg2, wg3, wg4 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Fundamental aspects of synthetic biology and chemical biology
  • Pharmacology
  • Cell biology
  • Structural
Zorec Robert
Univerza v Ljubljani, Medicinska fakulteta
SIwg21. Organelle biology and trafficking
2. Organelle biology and trafficking
3. 7. Physiology, Pathophysiology and Endocrinology
  • Cell biology
  • Biophysical
  • Pharmacology
1. electrophysiology
2. super-resolution microscopy
1. membrane fusion
2. astrocytes and neurodegeneration
3. cancer cell vaccine
Yvinec Romain
INRA
Website
FRwg1, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
1.
2.
3.
Rosenkilde Mette
UCPH
Website
DKwg1, wg2, wg3 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Biological chemistry
  • Pharmacology
  • Biochemical
  • Clinical
1. Signal transduction, biased signaling
2. kinetics and dynamics of receptor-ligand interactions
3. translational sciences
Castro Rui
Faculty of Pharmacy, University of Lisbon
Website
PTwg21. Metabolism, biological basis of metabolism-related disorders
2. Metabolism, biological basis of metabolism-related disorders
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Cell biology
  • Animal models
1. Liver Disease
2. microRNAs
3. biomarkers & therapies
Sencanski Milan
Vinča Institute of Nuclear Sciences
Website
RSwg31. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational
1. GPCRs
2. Chronic and infectious diseases
3. Drug repurposing
Filipek Slawomir
University of Warsaw
Website
PLwg1, wg2, wg3, wg4, wg51. Biocomputing and molecular computation
2. Biocomputing and molecular computation
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational
1. molecular modeling and dynamics
2. drug design
3. web-based tools
1. GPCRs
2. signaling and biased signaling
3. ligand gated ion channels
Mistry Shailesh
University of Nottingham
Website
GBwg31. Medicinal chemistry
2. Medicinal chemistry
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Chemistry
  • Chemistry
  • Chemistry
1. Peptide and small molecule synthesis
2. Drug discovery
3. Chemical tool development (e.g. fluorescent ligands)
1. GPCRs
2. Allosteric and orthosteric ligands
3. Fluorescent probes
Prömel Simone
Universität Leipzig
Website
DEwg1, wg2 1. Biochemistry
2. Biochemistry
3. Developmental genetics in animals and plants
  • Cell biology
  • Biochemical
  • Animal models
1. Adhesion GPCRs
2. Signalling
3. Physiological functions
Miljus Tamara
University of Birmingham
GBwg11. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Molecular mechanisms of signalling pathways
  • Biophysical
  • Biochemical
  • Structural
1.
2.
3.
Hansen Trond Vidar
University of Oslo
Website
NOwg31. 2. Physics and Chemistry
2. 2. Physics and Chemistry
3. Biological chemistry
  • Chemistry
  • Structural
  • Biochemical
1. Organic chemistry
2. Lipids
3. GPCRs
1. Medicinal chemistry
2. Agonists
3. Resolution of inflammation
Kukaj Taulant
Friedrisch Schiller University Jena
DEwg11. Molecular architecture and structure
2. Molecular architecture and structure
3. Medicinal chemistry
  • Biophysical
  • Cell biology
  • Pharmacology
Møller Thor
University of Copenhagen
DKwg1, wg3, wg41. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Pharmacology
  • Pharmacology
  • Biophysical
1. Second messenger signaling assays
2. Receptor trafficking
3. Fluorescence microscopy
1. Receptor trafficking
2. Intracellular signaling
3. Biosensors
Waldhoer Maria
InterAx Biotech
Website
CHwg2, wg4 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Computational biology
  • Pharmacology
  • Cell biology
  • Computational
FOGEL Wieslawa Agnieszka
Medical University of Lodz
Website
PLwg21. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Animal models
  • Pharmacology
  • Biochemical
1. animal models
2. Biochemical Pharmacology
3. behavioral
1. CNS disorders
2. animal models
3. GPCRs ligands
leroy xavier
Domain Therapeutics
Website
FRwg1, wg2, wg3, wg4, wg5 1. Innate immunity
2. Innate immunity
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Pharmacology
  • Biochemical
  • Animal models
1. BRET; Spatiotemparal; GPCRs
2. Inflammasome
3. Immuno oncology
Stefanachi, Angela
Università degli studi di Bari Aldo Moro
Website
ITWG3, WG41. Medicinal chemistry
2. Organic chemistry
3. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions
  • Chemistry
  • Cell biology
  • Computational

1. parallel synthesis
2. GPCR
3. Crystal structures
1. CB2
2. Cancer
3. Neurodegeneration
Paparde, Artūrs
Rīga Stradiņš university
Website
LVWG21. Fundamental mechanisms underlying cardiovascular diseases
2. Comparative physiology and pathophysiology
3. Organ physiology and pathophysiology
  • Computational
  • Computational
  • Computational

1. Atherosclerosis
2. Cardiovascular adaptation
3. (Patho-) physiology of atherosclerosis
Plouffe, Bianca
Queen's University Belfast
Website
GBWG2, WG31. Cell signalling and signal transduction
2. Fundamental mechanisms underlying cancer
3. Fundamental mechanisms underlying cardiovascular diseases
  • Pharmacology
  • Cell biology
  • Cell biology

1. GPCRs
2. compartmentalised G protein signalling
3. compartmentalised G protein signalling
1. Compartmentalised G protein signalling
2. GPCR signalling
Tautermann, Christofer
Boehringer Ingelheim Pharma GmbH & Co KG
ALWG2, WG31. Theoretical and computational chemistry
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Computational

1. Homology Modeling
2. MD simulations
3. Quantum Chemistry
1. Drug design
2. Computational chemistry
3. GPCR models
Gloriam, David
University of Copenhagen
DKWG3, WG51. Web and information systems, database systems
2. Theoretical and computational chemistry
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Computational
  • Structural
  • Pharmacology

1. open access databases
2. structure determination
3. ligand identification and optimisation
1. Open access databases
2. Computational drug design
3. Structure determination
Carlsson, Jens
Uppsala University
Website
SEWG3, WG4, WG51. Bioinformatics
2. Medicinal chemistry
3. Theoretical and computational chemistry
  • Computational
  • Computational
  • Computational

1. Virtual screening (Molecular docking)
2. Molecular dynamics simulations
3. Homology modeling
1. Polypharmacology/Selective/Biased ligands
2. Structural basis of GPCR activation
3. Accurate structural models of ALL GPCRs
Bennett, Kirstie
Sosei Heptares
Website
GBWG31. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Cellular and Developmental Biology
3. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Computational

1. GPCR
2. Molecular Pharmacology
Wessel Andressen, Kjetil
University of Oslo
Website
NOWG11. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Biophysical
  • Biophysical
  • Pharmacology

1. FRET
2. biosensor cGMP
3. biosensors
1. cGMP
2. 5-HT7 receptor
3. Cardiomyocyte
Lazar, Josef
Institute of Organic Chemistry and Biochemistry CAS
Website
CZWG1, WG2, WG3, WG41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Cell signalling and signal transduction
3. Spectroscopic and spectrometric techniques
  • Biophysical
  • Cell biology
  • Structural

1. polarization microscopy
2. G protein signaling
1. Cell signaling
2. Advanced optical microscopy
3. G proteins
Canals, Meritxell
University of Nottingham
GBWG1, WG2, WG3, WG41. Molecular mechanisms of signalling pathways
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Pharmacology
  • Cell biology
  • Biochemical

1. Opioid receptors
2. GPCRs
3. Signalling
Radi, Marco
University of Parma
Website
ITWG31. Medicinal chemistry
2. Method development in chemistry
3. Organic chemistry
  • Chemistry
  • Small molecules
  • Docking

1. small molecules
2. docking
3. combinatorial chemistry
1. CCR6
2. CXCR4
3. GPER-1
Contino, Marialessandra
University of Bari
ITWG3, WG41. Biological chemistry
2. Molecular mechanisms of signalling pathways
3. Neurological disorders
  • Pharmacology
  • Biochemical
  • Cell biology

1. GPCRs
2. GPCRs
3. GPCRs
1. GPCRs
2. Cancer
3. Neurodegeneration
Dubiel, Mariam
Heinrich Heine University of Duesseldorf
Website
DEWG11. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Neurological disorders
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Biochemical
  • Chemistry

Chabbert, Marie
CNRS
FRWG11. Computational biology
2. Molecular mechanisms of signalling pathways
3. Bioinformatics
  • Computational
  • Structural
  • Biophysical

1. GPCR
2. Biased Signaling
3. Molecular Simulations
Fardilha, Margarida
University of Aveiro
Website
PTWG2, WG31. Biochemistry
2. Genetics, ’Omics’, Bioinformatics and Systems Biology
3. Physiology, Pathophysiology and Endocrinology
  • Biochemical
  • Cell biology
  • Clinical

1. Male reproduction
2. Sperm motility
3. Protein phosphatase 1
Solano, Maria Marti
MRC Laboratory of Molecular Biology
GBWG1, WG31. Molecular mechanisms of signalling pathways
2. Computational biology
3. Systems biology
  • Computational
  • Structural
  • Pharmacology

1. Pharmacogenomics
2. Signalling bias
3. Structural Biology
Corminboeuf, Olivier
Idorsia Pharmaceuticals Ltd
Website
FRWG1, WG2, WG3, WG41. Medicinal chemistry
2. Immunological mechanisms in disease
3. Pharmacology and pharmacogenomics
  • Chemistry
  • Biochemical
  • Pharmacology

1. Medicinal Chemistry
2. Oncology
3. Immunology
D'Ursi, Pasqualina
National Research Council
Website
ITWG11. Molecular architecture and structure
2. Bioinformatics
3. Medicinal chemistry
  • Structural
  • Biochemical
  • Pharmacology

1. Protein
2. Function
3. drug design
1. Bionformatics
2. Protein structure activity
3. Drug design
Dr. Henri Xhaard
University of Helsinki
FIWG3, WG51. Molecular architecture and structure
2. Bioinformatics
3. Web and information systems, database systems
  • Computational
  • Structural
  • Biochemical

1. Databases for sequence/structure analysis
2. Protein and protein-ligand complexes modeling
3. Virtual ligand screening and design
1. Machine learning
2. Ligand design
3. Structural modeling
Kiec-Kononowicz Katarzyna
Jagiellonian University
PLwg31. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
1. medicinal chemistry
2. GPCRs
3. drug-like properties
Kozielewicz Pawel
Karolinska Institutet
SEwg2, wg3 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Biocomputing and molecular computation
  • Pharmacology
  • Cell biology
  • Computational
1. Receptors
2. signaling
3. molecular dynamics
1. GPCRs
2. small ligands
3. drug discovery
Frank Philippe
University of Tours
Website
FRwg1, wg2, wg3, wg4, wg5 1. Fundamental mechanisms underlying cancer
2. Fundamental mechanisms underlying cancer
3. Fundamental mechanisms underlying cardiovascular diseases
  • Animal models
  • Cell biology
  • Biochemical
1. Breast cancer model
2. Lipid metabolism
3. Lipid quantitification
1. Breast Cancer
2. Cholesterol metabolism
3. Atherosclerosis
Leurs Rob
Vrije Universiteit
falsewg1, wg2, wg3, wg41. 1. Mathematics (applications in science and industry)
2. 1. Mathematics (applications in science and industry)
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Chemistry
  • Computational
1. histamine receptors
2. chemokine receptors
Schiedel Anke
University of Bonn
DEwg1, wg2 1. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Cell biology
  • Pharmacology
  • Computational
1. GPCR
2. signal transduction
3. protein protein interactions
Sposini Silvia
CNRS
FRwg1, wg2, wg3, wg4, wg5 1. Organelle biology and trafficking
2. Organelle biology and trafficking
3. Cell signalling and signal transduction
  • Biophysical
  • Pharmacology
  • Cell biology
1. TIRF microscopy
2. Receptor Signalling
3. Neuronal cultures
1. GPCR
2. Membrane Trafficking
3. Endosomal signalling
Bradley Sophie
University of Glasgow
GBwg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. 1. Mathematics (applications in science and industry)
  • Pharmacology
  • Behavioral
  • Animal models
Garcia-Sosa Alfonso T.
University of Tartu
Website
EEwg3, wg5 1. Theoretical and computational chemistry
2. Theoretical and computational chemistry
3. Medicinal chemistry
  • Computational
  • Computational
  • Computational
1. drug design
2. drug discovery
3. molecular simulation
Tunaru Sorin
Institute of Biochemistry, Romanian Academy
ALwg2, wg3 1. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Lipid biology
  • Pharmacology
  • Cell biology
  • Biochemical
1. orphan GPCR, drug discovery, assay development
2. lipolysis, pancreatic beta cells, insulin signaling
3. ligand purification,
1. obesity
2. drug addiction
3. neurodegeneration
Uldrijan Stjepan
Masaryk University
Website
CZwg2, wg3 1. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Cell cycle, division and growth
  • Cell biology
  • Biochemical
  • Pharmacology
1. Cell signaling
2. ERK pathway
3. Melanoma
Deupi Xavier
Paul Scherrer Institute
Website
CHwg1, wg2, wg51. Molecular architecture and structure
2. Molecular architecture and structure
3. Molecular mechanisms of signalling pathways
  • Computational
  • Structural
  • Biophysical
1. structural bioinformatics
2. homology modeling
3. molecular dynamics simulations
1. G protein-coupled receptors
2. Membrane proteins
3. Protein structure and dynamics
Murga, Cristina
Universidad Autónoma de Madrid
Website
ESWG2, WG31. Cell signalling and signal transduction
2. Metabolism, biological basis of metabolism-related disorders
3. Organ physiology and pathophysiology
  • Biochemical
  • Animal models
  • Cell biology

1. Western Blot
2. Glucose and Insulin tolerance tests
3. Immunofluorescence
1. Signalling
2. Pathophysiology
3. Metabolism
Kellenberger, Esther
Université de Strasbourg
Website
FRWG31. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Structural

1. virtual screening
2. docking
3. pharmacophore
1. Molecular recognition
2. Structure-activity relationship
3. G-protein coupled receptor
Kandemis, Emine
Bahçeşehir University
Website
TRWG21. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Non-coding RNAs
  • Computational
  • Computational
  • Computational

1. Cell culture
2. Gene expression
3. Protein expression
1. Cancer Biology
2. Cell signaling
3. LncRNAs
Nyagulova Kandemish, Emilia
Bahçeşehir University
Website
ALWG21. Molecular mechanisms of signalling pathways
2. Non-coding RNAs
3. Cell signalling and signal transduction
  • Cell biology
  • Cell biology
  • Cell biology

1. Cell culture
2. Gene expression
3. Protein expression
1. Cell signaling
2. Cancer
3. Non-coding RNAs
Žerovnik, Eva
Institute "Jožef Stefan"
SIWG1, WG3, WG4, 1. Physical chemistry of biological systems
2. Biological chemistry
3. Nanophysics
  • Biochemical
  • Biophysical
  • Cell biology

1. CD, NMR
2. AFM, TEM, STED
3. Western blots, proteomics
1. Protein folding
2. Protein aggregation
3. Cascade of neurodegeneration
Hamann, Jörg
Amsterdam University Medical Centers
NLWG21. Immunological mechanisms in disease
2. Regulation and effector functions of the immune response
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Animal models
  • Clinical

1. Expression profiling
2. Zebrafish
3. Multiple sclerosis
1. Adhesion GPCRs
2. Microglia
3. T cells
M Keseru, György
Research Center for Natural Sciences
Website
HUWG31. Medicinal chemistry
2. Fundamental aspects of synthetic biology and chemical biology
3. Theoretical and computational chemistry
  • Chemistry
  • Chemistry
  • Computational

1. Medicinal chemistry
2. Chemical biology
3. Drug design
Bermudez, Marcel
Freie Universität Berlin
Website
DEWG1, WG3, WG51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational

1. virtual screening
2. molecular dynamics
3. drug design
1. GPCR pharmacology
2. Rational drug design
3. Signal tranduction
Capiod, Thierry
Université Paris-Descartes
Website
FRWG2, WG31. Cellular and Developmental Biology
2. Physiology, Pathophysiology and Endocrinology
3. Immunity and Infection
  • Cell biology
  • Cell biology
  • Biophysical

1. Prostate
2. Cancer
3. Calcium
Sommer, Martha
Charité Medical University Berlin
Website
DEWG1, WG21. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Biochemistry
  • Biophysical
  • Biochemical
  • Biochemical

1. Arrestin activation mechanism
2. Arrestin-GPCR interactions
3. Biological roles of arrestin
Stark, Holger
Heinrich Heine University Düsseldorf
Website
ALWG1, WG2, WG31. Cell signalling and signal transduction
2. Glycomics/Lipidomics
3. Neural cell function, communication and signalling, neurotransmission
  • Chemistry
  • Pharmacology
  • Biochemical

1. Drug design
2. GPCR screening
3. enzyme screening
1. Medicinal Chemistry
2. Drug development
3. Neurotransmitter
Mordalski, Stefan
University of Copenhagen
DKWG1, WG31. Molecular mechanisms of signalling pathways
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
Up to three techniques of expertise - First
  • Computational
  • Computational
  • Computational

Horvat Anemari
University of Ljubljana, Faculty of Medicine
SIwg1, wg2, wg3, wg4, wg51. Cell signalling and signal transduction
2. Cell signalling and signal transduction
3. Metabolism, biological basis of metabolism-related disorders
  • Cell biology
  • Animal models
  • Biochemical
1. Metabolism
2. cAMP and Ca2+ signaling
3. Neurodegeneration
Laurenzana Anna
University of Florence
ITwg21. Molecular mechanisms of signalling pathways
2. Molecular mechanisms of signalling pathways
3. Cell junctions, cell adhesion, cell communication and the extracellular matrix
  • Cell biology
  • Biochemical
  • Clinical
1. cell membrane receptors
2. protein immunoprecipitation
3. Xenograft models of human cancer
1. cell biology
2. molecular biology
3. cancer
Markus Muttenthaler
University of Vienna
Website
ATWG2, WG3, WG4, WG51. Biological chemistry
2. Medicinal chemistry
3. Pharmacology and pharmacogenomics
  • Chemistry
  • Pharmacology
  • Biochemical

1. Peptides
2. GPCRs and Ion channels
1. Neuropeptides
2. Venoms to Drugs
3. Medicinal Chemistry
Thorsen Thor S.
University of Copenhagen
Website
DKwg1, wg2, wg31. Molecular architecture and structure
2. Molecular architecture and structure
3. Physical chemistry of biological systems
  • Structural
  • Pharmacology
  • Cell biology
1. electron microscopy
2. drug design
3. signaling
1. membrane proteins
2. drug design
3. structure determination
Namasivayam Vigneshwaran
University of Bonn
DEwg3, wg4, wg51. Artificial intelligence, intelligent systems, multi agent systems
2. Artificial intelligence, intelligent systems, multi agent systems
3. Theoretical and computational chemistry
  • Computational
  • Computational
  • Computational
Cong, Xiaojing
Université Côte d'Azur
FRWG1, WG2, WG31. Theoretical and computational chemistry
2. Physical chemistry of biological systems
3. Bioinformatics
  • Computational
  • Biophysical
  • Chemistry

Franziska Heydenreich
Stanford University
USWG1, WG21. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Computational biology
  • Pharmacology
  • Biophysical
  • Computational

1. cell signalling
2. fluorescence
3. data science
1. Signalling
2. Conformations
vischer henry
Vrije Universiteit Amsterdam
NLwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Biological chemistry
3. Medicinal chemistry
  • Cell biology
  • Pharmacology
  • Computational
Heydenreich Franziska
Stanford University
wg1, wg21. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Computational biology
  • Pharmacology
  • Biophysical
  • Computational
1. cell signalling
2. fluorescence
3. data science
1. signalling
2. conformations
Scarpa Miriam
University of Glasgow
GBwg2, wg31. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Neurological disorders
  • Biochemical
  • Pharmacology
  • Behavioral
Schöneberg Torsten
Leipzig University
ALwg2, wg31. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Evolutionary genetics
  • Biochemical
  • Animal models
  • Pharmacology
Łażewska Dorota
Jagiellonian University Medical College
PLwg2, wg31. Medicinal chemistry
2. Medicinal chemistry
3. Organic chemistry
  • Chemistry
  • Chemistry
  • Chemistry
1. synthesis of GPCR ligands
2. medicinal chemistry
1. GPCR ligands
2. CNS disorders
3. drug synthesis
Esguerra Neira Mauricio
University of Copenhagen
DKwg1, wg51. Web and information systems, database systems
2. Molecular mechanisms of signalling pathways
3. Computational biology
  • Computational
  • Chemistry
  • Structural
1. gpcr
2. knowledge based analysis
3. interaction networks and prediction
Chevillard Florent
Idorsia Pharmaceuticals Ltd
wg3, wg4, wg51. Theoretical and computational chemistry
2. Machine learning
3. Bioinformatics
  • Computational
  • Pharmacology
  • Biochemical
1. Fragment
2. GPCR
3. Modeling
Doğan Berna
Bahcesehir University
TRwg1, wg2, wg3, wg41. Physical chemistry
2. Theoretical and computational chemistry
3. Machine learning
  • Computational
  • Computational
  • Computational
Gentry Patrick
University of Copenhagen
DKwg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular mechanisms of signalling pathways
3. Medicinal chemistry
  • Pharmacology
  • Chemistry
  • Computational
1. GPCR
2. Medicinal Chemistry
1. GPCR
2. Orphan receptors
3. Allosteric modulators
O'Brien Shannon
University of Birmingham
GBwg1, wg21. Molecular mechanisms of signalling pathways
2. Metabolism, biological basis of metabolism-related disorders
3. Molecular aspects of endocrinology
  • Pharmacology
  • Cell biology
  • Computational
1. G protein-coupled receptors
2. cell signalling
3. protein-protein interactions
Gabrielsen Mari
UiT Arctic University of Norway
NOwg31. Theoretical and computational chemistry
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Psychiatric disorders
  • Computational
  • Pharmacology
  • Computational
1. GPCRs
2. Molecular modelling
3. Pharmacology
Russotto Clizia
UiT - Arctic University of Norway
NOwg1, wg2, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Scientific computing, simulation and modelling tools
3. Imaging for medical diagnosis
  • Computational
  • Computational
  • Computational
1. molecular modelling

1. P.E.T. radioactive tracers
2. GnR-Hr
3. Glioblastoma
Koszegi Zsombor
University of Birmingham
GBwg11. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Cell biology
  • Biochemical
  • Computational
1. single-molecule
2. microscopy
1. single-molecule
2. TIRF
3. GPCR
Middleton Daniel
University of Copenhagen
DKwg1, wg3, wg41. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Structural
  • Biochemical
  • Pharmacology
Lanoiselée Yann
University of Birmingham
GBwg1, wg2, wg3, wg41. 1. Mathematics (applications in science and industry)
2. Statistical physics
3. Physics of biological systems
  • Computational
  • Biophysical
  • Computational
1. diffusion
2. complex systems
3. inverse problems
Zarzycka Barbara
Vrije Universiteit Amsterdam
NLwg3, wg4, wg51. Scientific computing, simulation and modelling tools
2. Scientific computing, simulation and modelling tools
3. Molecular architecture and structure
  • Computational
  • Structural
  • Biophysical
1. computer-aided drug design
2. molecular modulators
3. medicinal chemistry
Andric Silvana
Faculty of Sciences, University of Novi Sad
ALwg21. Cell signalling and signal transduction
2. Molecular aspects of endocrinology
3. Molecular mechanisms of signalling pathways
  • Animal models
  • Cell biology
  • Biochemical
Bećin Alisa
University of Novi Sad (UNS)
RSwg21. Cell signalling and signal transduction
2. Molecular mechanisms of signalling pathways
3. Molecular aspects of endocrinology
  • Cell biology
  • Cell biology
  • Cell biology
1. Transcriptomic analysis
2. Photometric analysis
3. Immuno assays
1. Chronobiology
2. Stress
3. Leydig cells
Radovic Pletikosic Sava
University of Novi Sad
RSwg21. Molecular aspects of endocrinology
2. Cell signalling and signal transduction
3. Molecular mechanisms of signalling pathways
  • Animal models
  • Cell biology
  • Biochemical
1. knockout mice
2. RNA/DNA/protein manipulation and analyses
3. enzyme immunoassays
1. mitochondrial dynamics
2. steroidogenesis
3. insulin and IGF1 receptors
Marinković Dijana
University of Novi Sad, Serbia
RSwg21. Cell signalling and signal transduction
2. Molecular aspects of endocrinology
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Cell biology
  • Biochemical
1. DNA/RNA/protein manipulation

1. Chronobiology
2. Leydig cells
Miljus Tamara
University of Birmingham
GBwg1, wg31. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Biochemistry
  • Biophysical
  • Structural
  • Pharmacology
1. GPCRs
2. biased signalling
3. molecular basis of GPCR signalling
Harwood Clare
University of Nottingham
GBwg11. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Pharmacology
  • Biochemical
  • Computational
1. molecular efficacy
2. single molecule pharmacology
Ambriović-Ristov Andreja
Ruđer Bošković Institute
HRwg1, wg21. Cell junctions, cell adhesion, cell communication and the extracellular matrix
2. Cytoskeleton and cell behaviour
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Cell biology
  • Biophysical
1. adhesome analysis using proteomics
2. in vitro cell migration and invasion
3. immunofluorescence
1. integrin adhesion complexes
2. cancer
3. crosstalk between GPCRs and integrins
Hanson Julien
University of Liège
BEwg1, wg2, wg3, wg41. Cell signalling and signal transduction
2. Organ physiology and pathophysiology
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Pharmacology
  • Cell biology
1. Complementation assay
2. BRET
3. GPCR
1. orphan GPCR
2. Endocrinology
3. Metabolism
CAPIOD Thierry
Université Paris-Descartes
FRwg2, wg31. 6. Cellular and Developmental Biology
2. 7. Physiology, Pathophysiology and Endocrinology
3. 9. Immunity and Infection
  • Cell biology
  • Cell biology
  • Biophysical
1. cancer
2. calcium-sensing receptor
3. calcium signaling
1. prostate
2. cancer
3. calcium
Rovira Xavier
University of Vic - Central University of Catalonia
ESwg1, wg2, wg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Photochemistry
  • Pharmacology
  • Cell biology
  • Structural
1. Molecular pharmacology
2. Receptor signalling
3. Ligand-receptor interactions
1. Photopharmacology
2. GPCR
3. Bias Signalling
Brünle Steffen
Paul Scherrer Institute
CHwg1, wg2, wg3, wg4, wg51. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Molecular mechanisms of signalling pathways
3. 1. Mathematics (applications in science and industry)
  • Structural
  • Biophysical
  • Biochemical
1. Protein X-ray Crystallography, Cryo-EM
2. Time-resolved X-ray crystallography
3. GPCR Signal Transduction
1. Structural Biology on GPCRs
2. Allosteric Modulation of GPCRs
3. Drug-discovery
Flavia Autore
Spari Heptares
UKwg1, wg2, wg41. Mathematics (applications in science and industry)
2. Mathematics (applications in science and industry)
3. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational
Minos Matsoukas
University of Patras
GRwg1, wg31. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Biocomputing and molecular computation
3. Bioinformatics
  • Computational
  • Structural
  • Pharmacology
Maiju Rinne
University of Helsinki
FIwg31. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
3. Medicinal chemistry

  • Pharmacology

  • Computational

  • Biochemical

1. Drug discovery
2. Structure modeling
3. Signaling pathways
1. GPCR evolution
2. Orexin system
3. Structural modeling
Christoffer K. Goth
University of Copenhagen
DKwg2, wg3, wg41. Cell signalling and signal transduction
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Glycobiology
  • Cell biology
  • Pharmacology
  • Biochemical

1. Chemokine receptors
2. Post translation modifications
3. Biased signaling
Szalai Rebeca Diez-Alarcia
University of the Basque Country UPV/EHU
Website
ESwg1, wg2, wg31. Neural cell function, communication and signalling, neurotransmission
2. Psychiatric disorders
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Pharmacology
  • Biochemical
  • Animal models

1. Neuropyschopharmacology
2. GPCR
3. Cell signaling
Jesús Giraldo
Universitat Autònoma de Barcelona
Website
ESwg1, wg2, wg31. Biocomputing and molecular computation
2. Molecular mechanisms of signalling pathways
3. Biological chemistry
  • Computational
  • Pharmacology
  • Chemistry

1. GPCR allostery and dynamics
2. Quantitative pharmacology
3. Drug design
1. GPCR oligomerization
2. GPCR allostery
3. GPCR dynamics
Linda Johansson
University of Gothenburg
SEwg1, wg2, wg31. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
2. Molecular mechanisms of signalling pathways
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Structural
  • Biophysical
  • Pharmacology

1. Crystallography
2. Cryo-EM
3. Signaling assays
1. Structural determination of GPCRs
2. GPCR dimerization
3. Orphan GPCRs
Jacopo Tricomi
University of Florence
ITwg11. Organic chemistry
2. Glycobiology
3. Biological chemistry
  • Chemistry
  • Computational
  • Computational

Banu Aydin
Marmara U School of Medicine
Website
TRwg1, wg2, wg31. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Metabolism, biological basis of metabolism-related disorders
  • Cell biology
  • Pharmacology
  • Computational

1. Cell signaling
2. Cell proliferation
3. Cancer
Christa Müller
University of Bonn
Website
DEwg1, wg2, wg3,wg41. Medicinal chemistry
2. Biological chemistry
3. Cell signalling and signal transduction
  • Chemistry
  • Pharmacology
  • Cell biology

1. Drug development
2. GPCRs and ectonucleotidases
3. Purinergic signaling
1. Purines and their membrane targets
2. Orphan GPCRs
3. Ectonucleotidases
Szalai Bence
Semmelweis University
ALwg1, wg21. Systems biology
2. Computational biology
3. Transcriptomics
  • Computational
  • Pharmacology
  • Computational
1. perturbation transcriptomics
2. cancer drug sensitivity
3. machine learning
1. perturbation gene expression profiles
2. role in GPCRs in cancer
3. drug repurposing
Georgi Kanev
InterAx
CHwg1, wg41. Artificial intelligence, intelligent systems, multi agent systems
2. Bioinformatics
3. Structural biology and its methodologies
  • Computational
  • Structural
  • Chemistry
1. Machine learning
2. Ligand binding
3. Cheminformatics
1. Deep learning
2. Virtual screening
3. ADRB2
Marta Busnelli
CNR
ITwg1, wg2, wg31. Cell signalling and signal transduction
2. Biological chemistry
3. Neural cell function, communication and signalling, neurotransmission
  • Pharmacology
  • Biochemical
  • Animal models
1. oxytocin/vasopressin receptor
2. functional selective agonists
3. cell signalling
Belgin BUYUKAKILLI
Mersin University
TRwg21. Physics of biological systems
2. Neural cell function, communication and signalling, neurotransmission
3. Neurological disorders
  • Biophysical
  • Animal models
  • Biophysical
1. Neurobiopyhsics
2. ischemia-reperfusion, alzheimer
3. Cell biophysic
1. Motor dysfunction
2. Neuropathy
3. Hypoxic-ischemic injury
Maxime Louet
Université de Montpellier
FRwg1, wg31. Molecular architecture and structure
2. Theoretical and computational chemistry
3. Physics of biological systems
  • Computational
  • Structural
  • Biophysical
1. Molecular Modeling
2. Membrane protein structure
3. Conformational ensemble
1. GPCR
2. protein-protein interactions
3. protein motions
Nicolas Floquet
Centre National de la Recherche Scientifique (CNRS)
FRwg1, wg31. Molecular architecture and structure
2. Theoretical and computational chemistry
3. Physics of biological systems
  • Computational
  • Structural
  • Biophysical
1. Molecular Dynamics Simulations
2. Analysis of Structures
3. Conformational ensembles
1. GPCR
2. protein-protein interactions
3. ligand design and selectivity
Bernard Masri
Institut Cochin - INSERM U1016
FRwg1, wg31. Molecular aspects of endocrinology
2. Fundamental mechanisms underlying cancer
3. Fundamental mechanisms underlying cardiovascular diseases
  • Cell biology
  • Pharmacology
  • Computational
1. Resonance Energy Transfer 1. GPCR
2. Signaling
3. Cancer
Rita Melo
Instituto Superior Tecnico
PTwg1, wg3, wg4,wg51. Theoretical and computational chemistry
2. Computational biology
3. Machine learning
  • Biochemical
  • Structural
  • Computational
1. drug design
2. protein-protein interface
3. machine learning
1. molecular modeling
2. protein-protein interface
3. machine learning
Necla Birgül
Bogazici University
TRwg21. Molecular genetics, reverse genetics, forward genetics, genome editing
2. Computational biology
3. Cell signalling and signal transduction
  • Cell biology
  • Structural
  • Behavioral
1. Cell culture
2. Molecular Dynamic and Simulation
3. Knock-out
1. Deorphanising GPCRs
2. CRISPR/Cas9 technology
3. Purification of ligands
Nuska Tschammer
Crelux, a WuXi AppTec Company
DEwg41. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Medicinal chemistry
3. Pharmacology and pharmacogenomics
  • Biophysical
  • Biochemical
  • Structural
1. MicroScale Thermophoresis
2. FRET
1. Target-to-hit
2. DNA encoded libraries
3. Fragment screening
Claudia Stäubert
Leipzig University, Medical Faculty
DEwg1, wg2,1. Cell signalling and signal transduction
2. Biochemistry
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Pharmacology
  • Cell biology
1. Metabolism
2. GPCR
1. GPCR
2. Signaling, trafficking
3. Evolution, metabolism
Orkun Cevheroglu
Ankara University
ALwg1, wg2, wg3,wg41. Biochemistry
2. Molecular biophysics
3. Molecular mechanisms of signalling pathways
  • Biochemical
  • Pharmacology
  • Cell biology
Lucie Pellissier
PRC UMR INRAE CNRS university of Tours
FRwg1, wg2, wg3,wg41. Pharmacology and pharmacogenomics
2. Psychiatric disorders
3. Neuronal development, plasticity and regeneration
  • Pharmacology
  • Animal models
  • Cell biology
1. RNAseq
2. BRET
1. Autism
2. Oxytocin

COST

COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation.

COST Action CA18133

All cells face the vital challenge of sensing their environments and responding in appropriate ways. How are different signalling pathways activated and modulated in precise and reproducible ways? Filling this gap in knowledge is absolutely necessary to advance the next generation of pharmaceutical drugs.

COST Action

COST Action

Pulpit rock

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European Research Network on Signal Transduction