Member List

NameCountryWebsiteWGERC code Techniques of expertise Research interests
Alves, Isabel
U. of Bordeaux
PTWG1, WG21. Molecular biophysics
2. Biological chemistry
3. Psychiatric disorders
  • Biophysical/plasmon waveguide resonance
  • Biochemical/signal transduction cascades
  • Biophysical/Calorimetry

1. lipid impact in signal transduction
2. ligand-receptor interaactions
3. cryo EM, sensor technologies, in cell FRET
Kandemis, Emine
Bahçeşehir University
TRhttps://bit.ly/2MNhRKqWG21. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Non-coding RNAs
  • Computational
  • Computational
  • Computational

1. Cancer Biology
2. Cell signaling
3. LncRNAs
Corminboeuf, Olivier
Idorsia Pharmaceuticals Ltd
FRwww.idorsia.comWG1, WG2, WG3, WG41. Medicinal chemistry
2. Immunological mechanisms in disease
3. Pharmacology and pharmacogenomics
  • Chemistry
  • Biochemical
  • Pharmacology

1. Medicinal Chemistry
2. Oncology
3. Immunology
Carlsson, Jens
Uppsala University
SEhttp://www.carlssonlab.org WG3, WG4, WG51. Bioinformatics
2. Medicinal chemistry
3. Theoretical and computational chemistry
  • Computational
  • Computational
  • Computational

1. Polypharmacology/Selective/Biased ligands
2. Structural basis of GPCR activation
3. Accurate structural models of ALL GPCRs
Mordalski, Stefan
University of Copenhagen
DKWG1, WG31. Molecular mechanisms of signalling pathways
2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
Up to three techniques of expertise - First
  • Computational
  • Computational
  • Computational

Contino, Marialessandra
University of Bari
ITWG3, WG41. Biological chemistry
2. Molecular mechanisms of signalling pathways
3. Neurological disorders
  • Pharmacology
  • Biochemical
  • Cell biology

1. GPCRs
2. Cancer
3. Neurodegeneration
Sommer, Martha
Charité Medical University Berlin
DEhttps://biophysik.charite.deWG1, WG21. Molecular mechanisms of signalling pathways
2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
3. Biochemistry
  • Biophysical
  • Biochemical
  • Biochemical

1. Arrestin activation mechanism
2. Arrestin-GPCR interactions
3. Biological roles of arrestin
Hamann, Jörg
Amsterdam University Medical Centers
NLWG21. Immunological mechanisms in disease
2. Regulation and effector functions of the immune response
3. Molecular mechanisms of signalling pathways
  • Cell biology
  • Animal models
  • Clinical

1. Adhesion GPCRs
2. Microglia
3. T cells
Bennett, Kirstie
Sosei Heptares
GBwww.soseiheptares.comWG31. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Cellular and Developmental Biology
3. Mathematics (applications in science and industry)
  • Pharmacology
  • Cell biology
  • Computational

1. GPCR
2. Molecular Pharmacology
Tautermann, Christofer
Boehringer Ingelheim Pharma GmbH & Co KG
ALWG2, WG31. Theoretical and computational chemistry
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Computational

1. Drug design
2. Computational chemistry
3. GPCR models
Chabbert, Marie
CNRS
FRWG11. Computational biology
2. Molecular mechanisms of signalling pathways
3. Bioinformatics
  • Computational
  • Structural
  • Biophysical

1. GPCR
2. Biased Signaling
3. Molecular Simulations
Canals, Meritxell
University of Nottingham
GBWG1, WG2, WG3, WG41. Molecular mechanisms of signalling pathways
2. Pharmacology and pharmacogenomics (including drug discovery and design)
3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
  • Pharmacology
  • Cell biology
  • Biochemical

1. Opioid receptors
2. GPCRs
3. Signalling
Liebscher, Ines
Leipzig University
DEWG1, WG21. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Molecular mechanisms of signalling pathways
3. Biochemistry
  • Biochemical
  • Pharmacology
  • Animal models

1. Adhesion GPCR
2. Mechano-activation
3. Deorphanization
Solano, Maria Marti
MRC Laboratory of Molecular Biology
GBWG1, WG31. Molecular mechanisms of signalling pathways
2. Computational biology
3. Systems biology
  • Computational
  • Structural
  • Pharmacology

1. Pharmacogenomics
2. Signalling bias
3. Structural Biology
Kolb, Peter
Philipps-University Marburg
DEwww.kolblab.orgWG3, WG51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Pharmacology

1. Ligand selectivity
2. Prediction of affinity/efficacy/bias
3. Chemical universe
Hauser, Alexander
University of Copenhagen
DKWG1, WG2, WG3, WG4, WG51. Bioinformatics
2. Systems biology
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Computational
  • Structural
  • Biophysical

1. GPCRs
2. Pharmacogenomics
3. Structure Biology
Fardilha, Margarida
University of Aveiro
PTwww.ua.ptWG2, WG31. Biochemistry
2. Genetics, ’Omics’, Bioinformatics and Systems Biology
3. Physiology, Pathophysiology and Endocrinology
  • Biochemical
  • Cell biology
  • Clinical

1. Male reproduction
2. Sperm motility
3. Protein phosphatase 1
Žerovnik, Eva
Institute "Jožef Stefan"
SIWG1, WG3, WG4, 1. Physical chemistry of biological systems
2. Biological chemistry
3. Nanophysics
  • Biochemical
  • Biophysical
  • Cell biology

1. Protein folding
2. Protein aggregation
3. Cascade of neurodegeneration
Lazar, Josef
Institute of Organic Chemistry and Biochemistry CAS
CZwww.uochb.czWG1, WG2, WG3, WG41. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Cell signalling and signal transduction
3. Spectroscopic and spectrometric techniques
  • Biophysical
  • Cell biology
  • Structural

1. Cell signaling
2. Advanced optical microscopy
3. G proteins
Plouffe, Bianca
Queen's University Belfast
GBhttps://pure.qub.ac.uk/WG2, WG31. Cell signalling and signal transduction
2. Fundamental mechanisms underlying cancer
3. Fundamental mechanisms underlying cardiovascular diseases
  • Pharmacology
  • Cell biology
  • Cell biology

1. Compartmentalised G protein signalling
2. GPCR signalling
Paparde, Artūrs
Rīga Stradiņš university
LVwww.rsu.lvWG21. Fundamental mechanisms underlying cardiovascular diseases
2. Comparative physiology and pathophysiology
3. Organ physiology and pathophysiology
  • Computational
  • Computational
  • Computational

1. Atherosclerosis
2. Cardiovascular adaptation
3. (Patho-) physiology of atherosclerosis
Kellenberger, Esther
Université de Strasbourg
FRhttp://bioinfo-pharma.u-strasbg.frWG31. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Medicinal chemistry
3. Scientific computing, simulation and modelling tools
  • Computational
  • Structural
  • Structural

1. Molecular recognition
2. Structure-activity relationship
3. G-protein coupled receptor
D'Ursi, Pasqualina
National Research Council
ITwww.tb.cnr.itWG11. Molecular architecture and structure
2. Bioinformatics
3. Medicinal chemistry
  • Structural
  • Biochemical
  • Pharmacology

1. Bionformatics
2. Protein structure activity
3. Drug design
Tobin, Andrew
University of Glasgow
GBWG21. Cell signalling and signal transduction
2. Neural cell function, communication and signalling, neurotransmission
3. Pharmacology and pharmacogenomics (including drug discovery and design)
  • Biochemical
  • Pharmacology
  • Cell biology

1. Neuroscience
2. Gut physiology
3. Respiratory disease
Radi, Marco
University of Parma
IThttps://sites.google.com/site/marcoradiWG31. Medicinal chemistry
2. Method development in chemistry
3. Organic chemistry
  • Chemistry
  • Small molecules
  • Docking

1. CCR6
2. CXCR4
3. GPER-1
Murga, Cristina
Universidad Autónoma de Madrid
EShttp://cmurga.cbmso.esWG2, WG31. Cell signalling and signal transduction
2. Metabolism, biological basis of metabolism-related disorders
3. Organ physiology and pathophysiology
  • Biochemical
  • Animal models
  • Cell biology

1. Signalling
2. Pathophysiology
3. Metabolism
Nativi, Cristina
University of Florence
ITwww.unifi.itWG31. Organic chemistry
2. Glycomics/Lipidomics
3. Glycobiology
  • Chemistry
  • Computational
  • Computational

1. In vitro tests
2. Animal model
3. Glycobiology
Osborne, Greg
Heptares Therapeutics
GBwww.soseiheptares.comWG1, WG2, WG3, WG41. Mathematics (applications in science and industry)
2. Mathematics (applications in science and industry)
3. Mathematics (applications in science and industry)
  • Computational
  • Computational
  • Computational

Sotelo, Eddy
University of Santiago de Compostela
EShttps://www.sotelolab.esWG2, WG3, WG41. Medicinal chemistry
2. Biological chemistry
3. Fundamental aspects of synthetic biology and chemical biology
  • Chemistry
  • Chemistry
  • Pharmacology

1. Optimization of new ligands
2. New conjugation strategies
3. Biasedligands, allosteric modulators and bitopic ligands
Tate, Chris
MRC Laboratory of Molecular Biology
GBhttps://www2.mrc-lmb.cam.ac.uk/WG1, WG41. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics
2. Macromolecular complexes
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Structural
  • Biophysical
  • Biochemical

1. GPCR complexes
2. Structure
3. Dynamics
Bermudez, Marcel
Freie Universität Berlin
DEhttps://www.bcp.fu-berlin.deWG1, WG3, WG51. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Medicinal chemistry
3. Molecular mechanisms of signalling pathways
  • Computational
  • Computational
  • Computational

1. GPCR pharmacology
2. Rational drug design
3. Signal tranduction
Capiod, Thierry
Université Paris-Descartes
FRhttps://www.institut-necker-enfants-malades.fr/WG2, WG31. Cellular and Developmental Biology
2. Physiology, Pathophysiology and Endocrinology
3. Immunity and Infection
  • Cell biology
  • Cell biology
  • Biophysical

1. Prostate
2. Cancer
3. Calcium
Gmeiner, Peter
FAU
DEhttp://www.medchem.fau.de/gmeinerlab/WG31. Medicinal chemistry
2. Neurological disorders
3. Imaging for medical diagnosis
  • Chemistry
  • Pharmacology
  • Computational

1. GPCR ligands
2. Drug discovery
3. Structure based design
Krasel, Cornelius
Philipps-University Marburg
DEhttps://www.uni-marburg.de/de/fb16/ipkpWG11. Molecular mechanisms of signalling pathways
2. Cell signalling and signal transduction
3. Mathematics (applications in science and industry)
  • Pharmacology
  • Biochemical
  • Cell biology

Tikhonova, Irina
Queen's University Belfast
GBhttps://pure.qub.ac.uk/WG1, WG3, WG51. Computational biology
2. Fundamental aspects of synthetic biology and chemical biology
3. Biochemistry
  • Computational
  • Biochemical
  • Pharmacology

1. Allosteric sites
2. Dimerization
3. Drug design
Dubiel, Mariam
Heinrich Heine University of Duesseldorf
DEhttp://www.pharmazie.hhu.deWG11. Pharmacology and pharmacogenomics (including drug discovery and design)
2. Neurological disorders
3. Molecular mechanisms of signalling pathways
  • Pharmacology
  • Biochemical
  • Chemistry

Wessel Andressen, Kjetil
University of Oslo
NOhttps://www.med.uio.no/WG11. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence)
2. Molecular mechanisms of signalling pathways
3. Macromolecular complexes
  • Biophysical
  • Biophysical
  • Pharmacology

1. cGMP
2. 5-HT7 receptor
3. Cardiomyocyte
Stefanachi, Angela
Università degli studi di Bari Aldo Moro
IThttps://www.uniba.it/WG3, WG41. Medicinal chemistry
2. Organic chemistry
3. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions
  • Chemistry
  • Cell biology
  • Computational

1. CB2
2. Cancer
3. Neurodegeneration
Stark, Holger
Heinrich Heine University Düsseldorf
ALhttp://www.pharmazie.hhu.deWG1, WG2, WG31. Cell signalling and signal transduction
2. Glycomics/Lipidomics
3. Neural cell function, communication and signalling, neurotransmission
  • Chemistry
  • Pharmacology
  • Biochemical

1. Medicinal Chemistry
2. Drug development
3. Neurotransmitter
Cong, Xiaojing
Université Côte d'Azur
FRWG1, WG2, WG31. Theoretical and computational chemistry
2. Physical chemistry of biological systems
3. Bioinformatics
  • Computational
  • Biophysical
  • Chemistry

Nyagulova Kandemish, Emilia
Bahçeşehir University
ALhttp://akademik.bahcesehir.edu.trWG21. Molecular mechanisms of signalling pathways
2. Non-coding RNAs
3. Cell signalling and signal transduction
  • Cell biology
  • Cell biology
  • Cell biology

1. Cell signaling
2. Cancer
3. Non-coding RNAs
Gloriam, David
University of Copenhagen
DKWG3, WG51. Web and information systems, database systems
2. Theoretical and computational chemistry
3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies)
  • Computational
  • Structural
  • Pharmacology

1. Open access databases
2. Computational drug design
3. Structure determination
M Keseru, György
Research Center for Natural Sciences
HUhttp://medchem.ttk.hu/WG31. Medicinal chemistry
2. Fundamental aspects of synthetic biology and chemical biology
3. Theoretical and computational chemistry
  • Chemistry
  • Chemistry
  • Computational

1. Medicinal chemistry
2. Chemical biology
3. Drug design

COST

COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation.

COST Action CA18133

All cells face the vital challenge of sensing their environments and responding in appropriate ways. How are different signalling pathways activated and modulated in precise and reproducible ways? Filling this gap in knowledge is absolutely necessary to advance the next generation of pharmaceutical drugs.

COST Action

COST Action

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