| Name | Country | WG | ERC code | Techniques of expertise | Connected keyword of expertise | Research interests |
|---|---|---|---|---|---|---|
| Cordomí Arnau Universitat Autònoma de Barcelona | ES | WG1, WG3 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Macromolecular complexes |
| 1. EPR and Fluorescence spectroscopy 2. GPCR and transducer purification 3. X-ray crystallography | 1. dimers 2. signaling complexes 3. signal transduction |
| Dr. Daniel Hilger Philipps-Universität Marburg | DE | WG1, WG3 | 1. Molecular biophysics 2. Biochemistry 3. Structural biology and its methodologies |
| 1. Electron paramagnetic resonance 2. Protein purification 3. Crystallography | 1. Structure and dynamics of GPCRs and their complexes 2. Molecular basis of GPCR-mediated signaling 3. Drug development |
| Tikhonova, Irina Queen's University Belfast Website | GB | WG1, WG3, WG5 | 1. Computational biology 2. Fundamental aspects of synthetic biology and chemical biology 3. Biochemistry |
| 1. MD simulations 2. Virtual screening 3. Structure-function | 1. Allosteric sites 2. Dimerization 3. Drug design |
| Gmeiner, Peter FAU Website | DE | WG3 | 1. Medicinal chemistry 2. Neurological disorders 3. Imaging for medical diagnosis |
| 1. Synthesis 2. In vitro assays 3. Molecular dynamics | 1. GPCR ligands 2. Drug discovery 3. Structure based design |
| Kolb, Peter Philipps-University Marburg Website | DE | WG3, WG5 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Medicinal chemistry 3. Scientific computing, simulation and modelling tools |
| 1. Docking 2. Homology modelling | 1. Ligand selectivity 2. Prediction of affinity/efficacy/bias 3. Chemical universe |
| Rafael Franco Universitat de Barcelona | ES | WG1, WG2 | 1. Biological chemistry 2. Biochemistry 3. Neural cell function, communication and signalling, neurotransmission |
| ||
| Di Pizio Antonella Leibniz-Institute for Food Systems Biology at TUM Website | DE | wg1, wg3 | 1. Food sciences 2. Food sciences 3. Medicinal chemistry |
| ||
| Abatematteo Francesca Serena University of Bari Aldo Moro Website | IT | wg3, wg4 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Biological chemistry |
| 1. GPCRS 2. CB2 3. |
|
| Sztyler Agnieszka Charité Medical University Berlin Website | DE | wg1, wg2, wg3 | 1. Biochemistry 2. Biochemistry 3. Molecular mechanisms of signalling pathways |
| 1. Fluorescence spectroscopy | 1. GPCR 2. arrestin 3. signal transduction |
| Hauser, Alexander University of Copenhagen | DK | WG1, WG2, WG3, WG4, WG5 | 1. Bioinformatics 2. Systems biology 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Data science 2. Structure analysis | 1. GPCRs 2. Pharmacogenomics 3. Structure Biology |
| Tobin, Andrew University of Glasgow | GB | WG2 | 1. Cell signalling and signal transduction 2. Neural cell function, communication and signalling, neurotransmission 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Neuroscience 2. Gut physiology 3. Respiratory disease |
|
| Rinken Ago University of Tartu Website | EE | wg1, wg3, wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Ligand binding properties 2. Superresolution microscopy for receptors 3. Fluorescent probes for receptors | 1. kinetic mechanism of ligand binding 2. Regulation of ligand binding and signal transduction 3. Novel methods for receptor research |
| Shahraki Aida Philipps-University Marburg | DE | wg1 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. Computational biology |
| 1. high-throughput virtual screening 2. peptide-based agonists 3. structural studies |
|
| Isbilir Ali Max Delbrück Center for Molecular Medicine | DE | wg1, wg2, wg3, wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Molecular aspects of endocrinology |
| 1. Microscopy 2. Multiplexed 3. Biased | |
| Mamyrbekov Alibek University of Copenhagen | DK | wg5 | 1. Bioinformatics 2. Bioinformatics 3. Scientific computing, simulation and modelling tools |
| ||
| Kliewer Andrea University Hospital Jena | DE | wg2, wg3, wg4 | 1. Neural bases of behaviour 2. Neural bases of behaviour 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. pain/addiction behavior 2. opioids 3. genetic opioid receptor models | 1. 2. 3. |
| Bock Andreas Leipzig University Website | UK | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| 1. G protein-coupled receptors 2. cyclic nucleotides 3. FRET | 1. Compartmentalization 2. G protein-coupled receptors 3. Biomolecular condensates |
| Chevigné Andy Luxembourg Institute of Health | LU | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. GPCR 2. Chemokine 3. signaling |
|
| ALMERICO ANNA MARIA University of Palermo Website | IT | wg1, wg3, wg4 | 1. Method development in chemistry 2. Method development in chemistry 3. Bioinformatics |
| 1. molecular modelling 2. synthesis and drug design 3. mechanism of action of new drugs | 1. drug design and synthesis 2. QSAR and SAR analysis 3. antitumor/antivirus/antimicrobial agents |
| Kan Beki Acibadem Mehmet Ali Aydinlar University | TR | wg1, wg2 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Cell death (including senescence) and autophagy |
| 1. Signal transduction cascades, second messengers 3. protein structure and function | 1. GPCR signaling and G proteins 2. Neurodegeneration 3. Autophagy and mitophagy |
| Haran Tali Technion | IL | wg1 | 1. Molecular architecture and structure 2. Molecular architecture and structure 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. Affinity and stability measurements 2. Flexibility measurements 3. Analysis of NGS data | 1. Protein-DNA interactions 2. P53 functionality 3. Gene regulation |
| Bondar Alexey Center for Nanobiology and Structural Biology | CZ | wg1, wg2, wg4 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| 1. clathrin 2. single-molecule imaging 3. preassembly |
|
| Xu Bo uppsala university | SE | wg1, wg2, wg3, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Cell signalling and signal transduction 3. 12. Applied Life Sciences and Biotechnology |
| 1. in vitro pharmacology 2. cell culture and transfection 3. in situ proximity ligation assay | 1. signalling pathway 2. GPCR 3. biosensor development |
| Brkljačić Jelena Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade Website | RS | wg2, wg3 | 1. Molecular aspects of endocrinology 2. Molecular aspects of endocrinology 3. Metabolism, biological basis of metabolism-related disorders |
| 1. Glucocorticoid receptor 2. Redox signalling 3. Metabolic disorders |
|
| Rosano Camillo IRCCS Policlinico San Martino - Genova (I) | IT | wg1, wg2, wg3, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Scientific computing, simulation and modelling tools |
| 1. Crystallography 2. Molecular Simulations | 1. Oncology 2. Drug Design 3. |
| Cevheroglu Orkun Ankara University Website | TR | wg1, wg2, wg3, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. Cell signalling and signal transduction |
| 1. BRET 2. FRET 3. BiFC |
|
| de Graaf Chris Sosei Heptares Website | GB | wg1, wg2, wg3, wg4, wg5 | 1. Scientific computing, simulation and modelling tools 2. Scientific computing, simulation and modelling tools 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Cheminformatics 2. Computational Medicinal Chemistry 3. Structure-Based Drug Discovery | 1. G Protein-Coupled Receptors 2. Computer-Aided Drug Design 3. Structural Bioinformatics |
| Munk Christian Copenhagen University Website | DK | wg5 | 1. Bioinformatics 2. Bioinformatics 3. Machine learning |
| 1. GPCRs 2. Biased signalling 3. Structure analysis |
|
| MOREAU Christophe CNRS | FR | wg4 | 1. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds) 2. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds) 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. electrophysiology 2. protein engineering 3. Ion channel-coupled receptor | 1. electrical bionsensors 2. GPCRs 3. ion channel reporter |
| Bonnesen Cecilie University of Copenhagen | DK | wg1, wg2, wg3, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. |
| ||
| Maccallini Cristina University G. d'Annunzio of Chieti-Pescara | IT | wg3, wg4 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Analytical chemistry |
| 1. Synthesis 2. enzyme inhibition 3. nitric oxide | 1. Synthesis 2. small molecules 3. nitric oxide |
| Goudet Cyril Institut de Genomique Fonctionnelle Website | FR | wg1 | 1. Neural cell function, communication and signalling, neurotransmission 2. Neural cell function, communication and signalling, neurotransmission 3. Molecular mechanisms of signalling pathways |
| 1. Neuropharmacology 2. Photopharmacology 3. Chronic pain | 1. GPCR 2. Pain 3. Neuromodulation |
| Calebiro Davide University of Birmingham Website | GB | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Molecular aspects of endocrinology |
| 1. single-molecule microscopy 2. FRET 3. quantitative biology | 1. GPCRs 2. cAMP 3. signal compartmentalization |
| van der Es Daan Leiden University | false | wg3 | 1. Organic chemistry 2. Organic chemistry 3. Biological chemistry |
| 1. Organic Synthesis 2. Chemical Biology 3. Molecular Probes | |
| Abboud Dayana University of liege | BE | wg1, wg2, wg3 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Metabolism, biological basis of metabolism-related disorders |
| 1. GPCR 2. Orphan GPCR 3. Signal transduction |
|
| Kirovski Danijela University of Belgrade Website | RS | wg3 | 1. Molecular aspects of endocrinology 2. Molecular aspects of endocrinology 3. Metabolomics |
| 1. domestic animals 2. PCR technique 3. Loading tests | 1. Domestic animals 2. cell signaling 3. metabolism |
| Daniel Legler Biotechnology Institute Thurgau at the University of Konstanz | CH | WG1, WG2, WG3 | 1. Mathematics 2. Mathematics 3. Mathematics |
| 1. GPCR signaling 2. Chemokine 3. Cell migration |
|
| Ler Daria Eurofarm Centar Polyclinic Website | false | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Proteomics |
| 1. molecular biomarkers 2. cancer biology 3. |
|
| KELES Didem Izmir University of Economics | TR | wg2, wg3 | 1. Fundamental mechanisms underlying cancer 2. Fundamental mechanisms underlying cancer 3. Molecular mechanisms of signalling pathways |
| 1. Zymography 2. Western blotting 3. 3D spheroid | 1. Cancer metastasis and extracellular matrix 2. Drug repurposing 3. Voltage gated sodium channels and signaling |
| Djordjevic Ana Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade Website | RS | wg2, wg3 | 1. Molecular aspects of endocrinology 2. Molecular aspects of endocrinology 3. Molecular mechanisms of signalling pathways |
| 1. 2. 3. |
|
| DOGAN SONER Yeditepe University, School of Medicine Website | TR | wg2 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Epigenetics and gene regulation |
| 1. cancer mouse model 2. micro RNA array by afymetrix 3. Pyrosquencing | 1. Epigenetics 2. Ageing 3. Calorie restriction |
| Vojnović Milutinović Danijela Institute for Biological Research "Siniša Stanković"- National Institute of Republic of Serbia, University of Belgrade Website | RS | wg2, wg3 | 1. Molecular aspects of endocrinology 2. Molecular aspects of endocrinology 3. Molecular mechanisms of signalling pathways |
| 1. protein expression 2. metabolic disorders 3. histological analysis | 1. PCOS 2. glucocorticoids 3. insulin signaling pathway |
| Vavers Edijs Latvian Institute of Organic Synthesis Website | LV | wg3 | 1. Neurological disorders 2. Neurological disorders 3. Molecular mechanisms of signalling pathways |
| 1. Drug discovery, Molecular mechanisms, Screening 2. Stroke, Traumatic brain injury, Dementia, Epilepsy 3. Animal behaviour, Learning and memory, Depression, Anxiety, Pain perception, Neurological severity assessment | 1. Sigma-1 chaperone protein 2. Epileptogenesis 3. Novel compounds |
| Feeney Emma University College Dublin | IE | wg2 | 1. Sensation and perception 2. Sensation and perception 3. Epidemiology and public health |
| 1. Sensory evaluation 2. taste perception 3. psychophysics | 1. taste perception 2. sensory evaluation 3. food structure |
| Lacivita Enza University of Bary | IT | wg3 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Neuronal development, plasticity and regeneration |
| 1. GPCRs 2. neuroinflammation 3. biased agonism |
|
| Ghosh Eshan Copenhagen University Website | DK | wg1, wg3, wg4, wg5 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Fundamental aspects of synthetic biology and chemical biology |
| 1. Protein chemistry 2. Co-immunoprecipitation 3. Cryo-EM and Crystallography | 1. GPCR Structural Biology 2. Macromolecular Assembly 3. Protein Evolution |
| Moreno Estefanía University of Barcelona Website | ES | wg1, wg2 | 1. Biochemistry 2. Biochemistry 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Biophysical and immunological techniques 2. Functional techniques 3. Pharmacological techniques | 1. The biochemistry, physiology and pharmacology of G-protein coupled receptors 2. Heteromerization of G Protein Coupled Receptors 3. Neurodegenerative and neurological diseases |
| Tripp Emma University of Birmingham Website | GB | wg1, wg2, wg3, wg4, wg5 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Metabolism, biological basis of metabolism-related disorders |
| 1. Microscopy 2. BRET | 1. GPCRs 2. Cell signalling 3. Adipocytes |
| Finn Olav Levy University of Oslo Website | NO | WG1, WG2 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Fundamental mechanisms underlying cardiovascular diseases |
| 1. PDE assays 2. HFpEF 3. FRET | 1. Serotonin receptors 2. Cyclic nucleotides 3. Phosphodiesterases |
| Fierro Fabrizio Hebrew University | IL | wg1, wg3 | 1. Scientific computing, simulation and modelling tools 2. Scientific computing, simulation and modelling tools 3. Systems neuroscience and computational neuroscience |
| 1. Homology modelling 2. Docking 3. Molecular Dynamics | 1. GPCR 2. bitter taste receptors 3. |
| Ballante Flavio Uppsala University Website | SE | wg3, wg4, wg5 | 1. Theoretical and computational chemistry 2. Theoretical and computational chemistry 3. Scientific computing, simulation and modelling tools |
| 1. Structure-based drug design 2. Ligand-based drug design 3. Quantitative modelling | 1. Drug design 2. Computational chemistry 3. Medicinal chemistry |
| Wilhelm Florian ETH Zürich | CH | wg1, wg2, wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Physics of biological systems |
| 1. Atomic Force Microscopy 2. Ligand Binding 3. cellular FRET-based kinetic assays | 1. Arrestin 2. GPCR Phosphorylation 3. GPCR Signaling |
| Mayor Jr Federico Universidad Autónoma Madrid | ES | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| 1. 2. 3. |
|
| Acher Francine University Paris Descartes Website | FR | wg3 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Neurological disorders |
| 1. medicinal chemistry 2. neuropharmacology 3. molecular modeling | 1. glutamate 2. GPCRs 3. transporters |
| van Westen Gerard Leiden University (LACDR) Website | NL | wg3, wg4 | 1. Artificial intelligence, intelligent systems, multi agent systems 2. Artificial intelligence, intelligent systems, multi agent systems 3. Medicinal chemistry |
| 1. machine-learning 2. structure-based 3. proteochemometrics | 1. neural-networks 2. GPCRs 3. oncology |
| Wolber Gerhard Freie Universitaet Berlin | DE | wg3, wg4, wg5 | 1. Medicinal chemistry 2. Machine learning 3. |
| 1. virtual screening 2. dynophores 3. functional selectivity |
|
| Morra Giulia Consiglio Nazionale delle Ricerche | IT | wg1, wg3 | 1. Biocomputing and molecular computation 2. Biocomputing and molecular computation 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Modeling of allosteric phenomena 2. protein dynamics 3. Drug discovery |
|
| Innamorati Giulio University of Verona | IT | wg1, wg2, wg3 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| ||
| Mangiatordi Giuseppe Felice National Research Council | IT | wg1, wg2, wg3, wg4, wg5 | 1. Computational biology 2. Computational biology 3. Theoretical and computational chemistry |
| 1. Drug Design, Structure Prediction 2. QM/MM, ADMET 3. Molecular Dynamic Simulation | 1. Docking simulations 2. MD simulations 3. Cannabinoid receptors |
| Tatar Gizem Karadeniz Technical University | TR | wg2 | 1. Bioinformatics 2. Bioinformatics 3. Computational biology |
| 1. Computational Drug Design 2. Computational Biology and Bioinformatics 3. Molecular Biology and Genetics |
|
| Krause Gerd Leibniz-Forschungsinstitut für molekulare Pharmakologie (FMP) Website | DE | wg3, wg5 | 1. Molecular architecture and structure 2. Molecular architecture and structure 3. Molecular aspects of endocrinology |
| 1. molecular 2. bioinformatics 3. protein design | 1. membrane proteins 2. structure-function relationshipss 3. pharmacological intervention |
| Ladds Graham Cambridge | GB | wg1, wg2, wg3, wg4 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Molecular mechanisms of signalling pathways |
| 1. GPCRs 2. Modelling 3. Pharmacology |
|
| Guccione Salvatore Catania Website | IT | wg3 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Organic chemistry |
| 1. Drug Design 2. Drug synthesis 3. |
|
| Lebon Guillaume Montpellier Universsity | FR | wg1, wg2, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Macromolecular complexes |
| 1. Membrane protein 2. X-ray, cryoEM 3. GPCRs | 1. GPCRs signal transduction 2. Structural Biology 3. pharmacology |
| Çubukçuoğlu Deniz Günseli Ankara University | TR | wg1, wg2 | 1. Stem cell biology 2. Stem cell biology 3. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology |
| 1. cell culture 2. pcr, wb 3. microarray | 1. heart failure 2. heart rhythm 3. molecular signaling of cardiomyocytes |
| Dr. Henry Vischer Vrije Universiteit Amsterdam | NL | WG1, WG3, WG3, WG4 | 1. Cell signalling and signal transduction 2. Biological chemistry 3. Medicinal chemistry |
| ||
| Bräuner-Osborne Hans University of Copenhagen Website | DK | wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. 1. Mathematics (applications in science and industry) |
| 1. GPCR 2. molecular pharmacology 3. mechanism-of-action |
|
| Cabadak Hulya Marmara University School of Medicine | TR | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell cycle, division and growth 3. Cell death (including senescence) and autophagy |
| 1. Cell culture and western blotting 2. Signalling pathway detection with ELİSA (NO,cAMP,Ca etc.) 3. Nücleic acid isolation (DNA,RNA) ,Real time PCR, | 1. GPCR and G proteins, Cell growth and Death Pathway 2. Drug effects on GPCR and related signalling pathways |
| Biebermann Heike Charité Universitätsmedizin Berlin Website | DE | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| 1. signalling modulation 2. biased signaling 3. pathway selected ligands |
|
| Danielson Helena Uppsala University | SE | wg1, wg3, wg4 | 1. Biochemistry 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Molecular interactions 2. Molecular interactions | 1. Molecular interactions 2. Drug discovery 3. Method development |
| CASTEL Hélène University Rouen Normandie Website | FR | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Invasion 2. Transparization iDISCO 3. cell behavior | 1. Neuro-oncology 2. animal behavior 3. Cancer |
| Daver Henrik University of Copenhagen | DK | wg1, wg3 | 1. Theoretical and computational chemistry 2. Theoretical and computational chemistry 3. Molecular mechanisms of signalling pathways |
| 1. MD simulations 2. DFT calculations | 1. Protein-protein interactions 2. Computational drug design |
| Gutierrez de Teran Hugo Uppsala University Website | SE | wg3, wg4, wg5 | 1. Theoretical and computational chemistry 2. Theoretical and computational chemistry 3. Biocomputing and molecular computation |
| 1. Molecular Dynamics 2. Structural Bioinformatics 3. Free Energy Calculations | 1. GPCR 2. Free Energy 3. adenosine receptors |
| Erol Ismail Gebze Technical University | TR | wg1, wg4, wg5 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Biocomputing and molecular computation |
| 1. GPCRs 2. Molecular simulations 3. oligomerization |
|
| Iatrou Kostas National Centre for Scientific Research "Demokritos" Website | GR | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Sensation and perception |
| 1. cell-based screening systems 2. ligand binding assays 3. insect attraction-repellence assays | 1. insects 2. odorant receptors 3. olfactory function modulators |
| Simon Icaro Ariel University of Copenhagen | DK | wg1, wg2, wg3, wg4, wg5 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. Biocomputing and molecular computation |
| 1. Molecular dynamics 2. Structure-activity relationships 3. Homology modeling | 1. molecular modeling 2. gpcr 3. biased signalling |
| IJzerman Ad Leiden University | false | wg3 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Molecular mechanisms of signalling pathways |
| 1. GPCR, adenosine receptors 2. new chemical entities, chemical probes 3. homology modeling, (Q)SAR | 1. target binding kinetics 2. allosteric modulation 3. GPCR structure |
| Sylte Ingebrigt UiT The Arctic University of Norway | NO | wg1, wg3 | 1. Theoretical and computational chemistry 2. Molecular architecture and structure 3. Medicinal chemistry |
| 1. Virtual ligand screening 2. Molecular dynamics simulations 3. Homology modeling and in silico mutations | 1. G-protein coupled receptors 2. Transporter proteins 3. Molecular mechanisms |
| Moreira Irina Coimbra University Website | PT | wg1, wg4, wg5 | 1. Computational biology 2. Computational biology 3. Machine learning |
| 1. Deep-learning 2. Drug discovery 3. GPCR function-structure |
|
| Georgoussi Zafiroula-Iro National Centre for Sceintific Research "Demokritos" Website | GR | wg1, wg2, wg3, wg4, wg5 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Neural cell function, communication and signalling, neurotransmission |
| 1. GPCR function 2. Bias signaling 3. GPCR pharmacology | 1. Opioid receptors 2. G and RGS proteins and effectors 3. G protein signaling-dependent behaviors |
| Hanson Julien University of Liège Website | BE | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. orphan GPCR 2. Endocrinology 3. Metabolism |
|
| Grimes Jak University of Birmingham | GB | wg1, wg2, wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Physics of biological systems |
| 1. Single-Molecule Microscopy 2. GPCR 3. Cell-based assays | 1. single-particle tracking of GPCRs 2. Receptor Pharmacology 3. Computational analysis of receptor dynamics |
| golebiowski jerome U cote d azur Website | FR | wg3 | 1. Theoretical and computational chemistry 2. Theoretical and computational chemistry 3. Scientific computing, simulation and modelling tools |
| 1. smell 2. taste |
|
| García Nafría Javier Institute of Biocomputation and Physics of Complex Systems, University of Zaragoza | ES | wg1 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Macromolecular complexes |
| 1. membrane protein complexes 2. structural biology 3. cryo-EM |
|
| Mathiesen Jesper Zealand Pharma | DK | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Cell signalling and signal transduction |
| ||
| Tiemann Johanna University Leipzig | DE | wg1, wg2, wg3, wg4, wg5 | 1. Scientific computing, simulation and modelling tools 2. Scientific computing, simulation and modelling tools 3. Computer graphics, computer vision, multi media |
| 1. MD 2. Modeling 3. Design | 1. GPCR dynamics 2. Dynamic network 3. Knowledge collection |
| Blanco Canosa Juan Bautista Institute for Advanced Chemistry of Catalonia Website | ES | wg3, wg4 | 1. Biological chemistry 2. Biological chemistry 3. Organic chemistry |
| 1. Sonic Hedgehog 2. protein synthesis 3. posttranslation modifications |
|
| Villà-Freixa Jordi Universitat Internacional de Catalunya | ES | wg1, wg3 | 1. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions 2. Theoretical and computational chemistry 3. Fundamental aspects of synthetic biology and chemical biology |
| 1. Molecular Dynamics 2. Enzymes 3. Modelling | 1. Enzyme catalysis 2. Molecular modelling 3. Protein interactions |
| Voß Jan Hendrik University of Bonn | DE | wg1, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. |
| 1. Radioligand-binding experiments 2. Site-directed mutagenesis 3. Molecular dynamics | 1. Binding kinetics 2. Structure-function relationship 3. |
| Springael Jean-Yves Université Libre de Bruxelles Website | BE | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. 9. Immunity and Infection |
| 1. Binding (Caturation/Competition/Association-Dissociation kinetics) 2. Signaling (G prot/Arrestin/cAMP/Ca/MAPK/Endocytosis/Chemotaxis) 3. BRET | 1. GPCR 2. chemokine 3. BRET |
| Harpsøe Kasper University of Copenhagen Website | DK | wg3, wg5 | 1. Scientific computing, simulation and modelling tools 2. Scientific computing, simulation and modelling tools 3. Bioinformatics |
| 1. Ligand binding mode prediction 2. Molecular dynamics simulation 3. In silico prediction of protein mutagenesis | 1. Biased agonists 2. Inhibitors of G protein mediated signaling 3. Analysis of ligand binding determinants |
| Nemec Katarina Max Delbrück Center for Molecular Medicine Website | DE | wg1, wg2, wg3, wg4, wg5 | 1. Biological chemistry 2. Biological chemistry 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. GPCR 2. RAMP 3. HTS |
|
| Tate, Chris MRC Laboratory of Molecular Biology Website | GB | WG1, WG4 | 1. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Macromolecular complexes 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. cryo-EM & X-ray crystallography 2. ITC & SPR 3. Expression & purification | 1. GPCR complexes 2. Structure 3. Dynamics |
| Vachkova Ekaterina Trakia University Website | BG | wg1, wg2 | 1. Stem cell biology 2. Stem cell biology 3. Molecular mechanisms of signalling pathways |
| 1. isolation stem cells 2. aplication of stem cells and their products 3. nutritional factors | 1. stem cells 2. adipose tissue 3. regenerative medicine |
| Jonas Kim King’s College London | GB | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Molecular aspects of endocrinology |
| 1. Single molecule imaging 2. GPCR 3. GPCR | 1. GPCRs 2. Endocrinology 3. Cellular signalling |
| Krasel, Cornelius Philipps-University Marburg Website | DE | WG1 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Mathematics (applications in science and industry) |
| ||
| Nativi, Cristina University of Florence Website | IT | WG3 | 1. Organic chemistry 2. Glycomics/Lipidomics 3. Glycobiology |
| 1. In vitro tests 2. Animal model 3. Glycobiology |
|
| Sotelo, Eddy University of Santiago de Compostela Website | ES | WG2, WG3, WG4 | 1. Medicinal chemistry 2. Biological chemistry 3. Fundamental aspects of synthetic biology and chemical biology |
| 1. Synthesis ligands 2. conjugation strategies 3. GPCRs | 1. Optimization of new ligands 2. New conjugation strategies 3. Biasedligands, allosteric modulators and bitopic ligands |
| Osborne, Greg Heptares Therapeutics Website | GB | WG1, WG2, WG3, WG4 | 1. Mathematics (applications in science and industry) 2. Mathematics (applications in science and industry) 3. Mathematics (applications in science and industry) |
| ||
| Alves Isabel U. of Bordeaux | FR | wg1, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Spectroscopic and spectrometric techniques 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. plasmon resonance 2. calorimetry 3. signal transduction cascades | 1. lipid impact in signal transduction 2. membrane active peptides 3. receptor reconstitution in model membranes |
| Liebscher, Ines Leipzig University | DE | WG1, WG2 | 1. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| 1. Adhesion GPCR 2. Mechano-activation 3. Deorphanization |
|
| Dr. Julie Sanchez University of Nottingham | UK | WG1, WG2, WG3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics |
| 1. BRET - FRET 2. Fluorescent biosensors 3. Ligand characterisation | 1. GPCR signalling and modulation 2. GPCRs involved in CNS disorders and pain 3. Chemokine receptors |
| Nikolic Katarina University of Belgrade, Faculty of Pharmacy Website | RS | wg3, wg5 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Systems neuroscience and computational neuroscience |
| 1. Computer-Aided Drug Design 2. Molecular Dynamic Simulations 3. Virtual Screening | 1. serotonin receptors antagonists 2. alpha2/imidazoline receptor agonists 3. kinase inhibitors |
| Kosloff Mickey University of Haifa Website | IL | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Macromolecular complexes |
| 1. Structural bioinformatics | 1. G proteins, GAPs, effectors 2. Interaction specificity 3. Signaling complexes |
| Kostenis Evi University of Bonn | DE | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| 1. signal transduction 2. signal transduction 3. signal transduction | 1. GPCR 2. G Protein 3. signal transduction |
| Khakurel Krishna Institute of Physics | CZ | wg3, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Scientific computing, simulation and modelling tools |
| 1. MicroED, CryoEM 2. Data Analysis, Computational tools Development 3. Spectroscopy and microscopy | 1. 2. 3. |
| Chung Ka Young Sungkyunkwan University | false | wg1 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Cell signalling and signal transduction |
| 1. GPCR signaling 2. Protein conformation |
|
| Laasfeld Tõnis University of Tartu Website | EE | wg4, wg5 | 1. Method development in chemistry 2. Method development in chemistry 3. Systems biology |
| 1. GPCR 2. Ligand binding models 3. Bioimage analysis | 1. deep learning for bioimage analysis 2. superresolution microscopy 3. kinetic models of ligand binding |
| Lamghari Meriem Institute Of Biomedical Engineering/Institute for Research and Innovation in Health Sciences Website | PT | wg2 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. 7. Physiology, Pathophysiology and Endocrinology |
| 1. Microfluidic for cells communication studies 2. 3D cell culture models 3. Bioengineering | |
| Barki-Harrington Liza University of Haifa | IL | wg1, wg2, wg3 | 1. Protein synthesis, modification, turnover 2. Protein synthesis, modification, turnover 3. Biochemistry |
| 1. GPCR 2. cyclooxygenase 3. protease |
|
| Stoddart Leigh University of Nottingham | GB | wg3, wg4 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Resonance Energy Transfer (BRET, FRET) 2. Fluorescence correlation spectroscopy 3. Binding kinetics | 1. Binding kinetics 2. Membrane organisation of receptors 3. GPCR fluorescent ligands |
| pardo leonardo universidad autonoma de barcelona Website | ES | wg3, wg4 | 1. Computational biology 2. Computational biology 3. Bioinformatics |
| 1. molecular dynamics 2. virtual screening | 1. oligomerization 2. drug design |
| Nygaard Mads Mørup University of Copenhagen | DK | wg3 | 1. Scientific computing, simulation and modelling tools 2. Scientific computing, simulation and modelling tools 3. Biochemistry |
| 1. Peptides 2. Simulations |
|
| Leopoldo Marcello Università degli Studi di Bari Aldo Moro | IT | wg3, wg4 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Fundamental aspects of synthetic biology and chemical biology |
| 1. Allosteric modulators 2. Orphan Receptors 3. Biased agonists |
|
| Tahk Maris-Johanna University of Tartu Website | EE | wg2, wg3 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Biochemistry |
| 1. Genetically encoded FRET-based biosensors assays for cAMP and apoptosis 2. Fluorescence anisotropy 3. Making and using baculoviruses and BacMam systems | 1. Cell signaling pathways 2. Ligand-receptor interactions 3. Biosensors |
| martinez Karen University of Copenhagen | DK | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Surface science and nanostructures |
| 1. fluorescence microscopy | |
| Floor Martin University of Vic Website | ES | wg1, wg3, wg4 | 1. Biocomputing and molecular computation 2. Biocomputing and molecular computation 3. Fundamental aspects of synthetic biology and chemical biology |
| 1. Protein design 2. Enzyme design 3. Structural bioinformatics |
|
| Szpakowska Martyna Luxembourg Institute of Health | LU | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. GPCR 2. Chemokines |
|
| Niv Masha The Hebrew University of Jerusalem, Israel Website | IL | wg3, wg5 | 1. Biochemistry 2. Biochemistry 3. Food sciences |
| 1. homology modeling 2. sensory studies 3. chemoinformatics | 1. GPCRs 2. taste receptors 3. drug discovery |
| Vrecl Fazarinc Milka University of Ljubljana, Veterinary Faculty Website | SI | wg1 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Morphology and functional imaging of cells and tissues |
| 1. confocal microscopy 2. BRET 3. fluorometric measurements | 1. GPCRs 2. protein-protein interactions 3. ntracellular signaling |
| STOEBER MIRIAM University of Geneva Website | CH | wg1, wg2, wg3, wg4, wg5 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Microscopy | 1. Subcellular Location 2. Signal Transduction 3. Neuropharmacology |
| Misicka-Kesik Alekssandra University of Warsaw | PL | wg1 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Analytical chemistry |
| 1. HPLC MS 2. pain study | 1. bifuncional peptidomimetics 2. MOR, DOR 3. melanocortin MC4 receptors |
| Wozniak Monika University in Liege | BE | wg2, wg3, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. 6. Cellular and Developmental Biology |
| ||
| Grigorova Natalia Trakia University Website | BG | wg1, wg2 | 1. Metabolism, biological basis of metabolism-related disorders 2. Metabolism, biological basis of metabolism-related disorders 3. Food sciences |
| 1. obesity-related disorders 2. bioactive food additives 3. signal transduction |
|
| Vardjan Nina University of Ljubljana, Faculty of Medicine | SI | wg2 | 1. 8. Neuroscience and Neural Disorders 2. 8. Neuroscience and Neural Disorders 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. Fluorescence Microscopy, Live cell imaging, IHC, ICC 2. WB, Biochemical assays 3. Drosophila, Rodents (mouse, rat) - animal models of neurological disorders | 1. Astroglia physiology 2. GPCR-mediated cell signalling, metabolism, exocytosis 3. Neuorodegeneration |
| Saraiva Nuno Universidade Lusófona Website | PT | wg1, wg2, wg4 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Cytoskeleton and cell behaviour |
| 1. ROS and Ca2+ signalling 2. Cell motility 3. Cancer progression |
|
| Velickovic Natasa Institute for biological research Sinisa Stankovic Website | RS | wg2, wg3 | 1. Metabolism, biological basis of metabolism-related disorders 2. Metabolism, biological basis of metabolism-related disorders 3. Non-communicable diseases |
| 1. protein expression 2. animal model of metabolic disease 3. hormone analysis | 1. diabetes 2. hepatic metabolism 3. endocrinology |
| Sensoy Ozge Istanbul Medipol University | TR | wg1, wg2, wg3 | 1. Scientific computing, simulation and modelling tools 2. Scientific computing, simulation and modelling tools 3. Cell signalling and signal transduction |
| 1. Molecular dynamis simulation 2. Computational biophysics 3. Computational structural biology | 1. GPCR biased signaling 2. Neurological disorders 3. Cancer |
| Pascale Crépieux CNRS Website | FR | wg1, wg2 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Molecular aspects of endocrinology |
| 1. GPCR 2. VHH 3. Signaling Network | 1. GPCR 2. signaling networks 3. mRNA translation |
| Scheerer Patrick Charité - Universitätsmedizin Berlin Website | DE | wg1, wg2, wg3, wg4, wg5 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Protein X-ray Crystallography 2. Time-resolved Methods 3. Signal Transduction | 1. Structural biology and Dynamics on GPCRs 2. Activation mechanisms of GPCRs 3. GPCR Signal Transduction |
| Jockers Ralf University of Paris Website | FR | wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Cell signalling and signal transduction |
| 1. GPCR 2. Melatonin 3. Leptin |
|
| Reiner-Link David University of Copenhagen | DK | wg1, wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular mechanisms of signalling pathways 3. Biological chemistry |
| 1. Analytical GPCR Pharmacology 2. Biochemistry of Proteins 3. Spectroscopic Analytics | 1. Ligand-Receptor Binding Kinetics 2. Biased Signalling 3. Allosterism and GPCR Oligomerization |
| Lane Rob University of Nottingham Website | GB | wg1, wg2, wg3, wg4 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Fundamental aspects of synthetic biology and chemical biology |
| ||
| Zorec Robert Univerza v Ljubljani, Medicinska fakulteta | SI | wg2 | 1. Organelle biology and trafficking 2. Organelle biology and trafficking 3. 7. Physiology, Pathophysiology and Endocrinology |
| 1. electrophysiology 2. super-resolution microscopy | 1. membrane fusion 2. astrocytes and neurodegeneration 3. cancer cell vaccine |
| Yvinec Romain INRA Website | FR | wg1, wg4 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| 1. 2. 3. |
|
| Rosenkilde Mette UCPH Website | DK | wg1, wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. Biological chemistry |
| 1. Signal transduction, biased signaling 2. kinetics and dynamics of receptor-ligand interactions 3. translational sciences | |
| Castro Rui Faculty of Pharmacy, University of Lisbon Website | PT | wg2 | 1. Metabolism, biological basis of metabolism-related disorders 2. Metabolism, biological basis of metabolism-related disorders 3. Molecular mechanisms of signalling pathways |
| 1. Liver Disease 2. microRNAs 3. biomarkers & therapies |
|
| Sencanski Milan Vinča Institute of Nuclear Sciences Website | RS | wg3 | 1. Scientific computing, simulation and modelling tools 2. Scientific computing, simulation and modelling tools 3. Molecular mechanisms of signalling pathways |
| 1. GPCRs 2. Chronic and infectious diseases 3. Drug repurposing |
|
| Filipek Slawomir University of Warsaw Website | PL | wg1, wg2, wg3, wg4, wg5 | 1. Biocomputing and molecular computation 2. Biocomputing and molecular computation 3. Molecular mechanisms of signalling pathways |
| 1. molecular modeling and dynamics 2. drug design 3. web-based tools | 1. GPCRs 2. signaling and biased signaling 3. ligand gated ion channels |
| Mistry Shailesh University of Nottingham Website | GB | wg3 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Peptide and small molecule synthesis 2. Drug discovery 3. Chemical tool development (e.g. fluorescent ligands) | 1. GPCRs 2. Allosteric and orthosteric ligands 3. Fluorescent probes |
| Prömel Simone Universität Leipzig | DE | wg1, wg2 | 1. Biochemistry 2. Cell signalling and signal transduction 3. Developmental genetics in animals and plants |
| 1. Adhesion GPCRs 2. Signalling 3. Physiological functions |
|
| Hansen Trond Vidar University of Oslo Website | NO | wg3 | 1. 2. Physics and Chemistry 2. 2. Physics and Chemistry 3. Biological chemistry |
| 1. Organic chemistry 2. Lipids 3. GPCRs | 1. Medicinal chemistry 2. Agonists 3. Resolution of inflammation |
| Kukaj Taulant Friedrisch Schiller University Jena | DE | wg1 | 1. Molecular architecture and structure 2. Molecular architecture and structure 3. Medicinal chemistry |
| ||
| Møller Thor University of Copenhagen | DK | wg1, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Second messenger signaling assays 2. Receptor trafficking 3. Fluorescence microscopy | 1. Receptor trafficking 2. Intracellular signaling 3. Biosensors |
| Waldhoer Maria InterAx Biotech Website | CH | wg2, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Computational biology |
| ||
| FOGEL Wieslawa Agnieszka Medical University of Lodz Website | PL | wg2 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| 1. animal models 2. Biochemical Pharmacology 3. behavioral | 1. CNS disorders 2. animal models 3. GPCRs ligands |
| leroy xavier Domain Therapeutics | FR | wg1, wg2, wg3, wg4, wg5 | 1. Innate immunity 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Immunological mechanisms in disease |
| 1. BRET; Spatiotemparal; GPCRs 2. Inflammasome 3. Immuno oncology | 1. Immuno-oncology 2. GPCRs 3. Antibodies |
| Stefanachi, Angela Università degli studi di Bari Aldo Moro Website | IT | WG3, WG4 | 1. Medicinal chemistry 2. Organic chemistry 3. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions |
| 1. parallel synthesis 2. GPCR 3. Crystal structures | 1. CB2 2. Cancer 3. Neurodegeneration |
| Paparde, Artūrs Rīga Stradiņš university Website | LV | WG2 | 1. Fundamental mechanisms underlying cardiovascular diseases 2. Comparative physiology and pathophysiology 3. Organ physiology and pathophysiology |
| 1. Atherosclerosis 2. Cardiovascular adaptation 3. (Patho-) physiology of atherosclerosis |
|
| Plouffe, Bianca Queen's University Belfast Website | GB | WG2, WG3 | 1. Cell signalling and signal transduction 2. Fundamental mechanisms underlying cancer 3. Fundamental mechanisms underlying cardiovascular diseases |
| 1. GPCRs 2. compartmentalised G protein signalling 3. compartmentalised G protein signalling | 1. Compartmentalised G protein signalling 2. GPCR signalling |
| Tautermann, Christofer Boehringer Ingelheim Pharma GmbH & Co KG | DE | WG2, WG3 | 1. Theoretical and computational chemistry 2. Medicinal chemistry 3. Scientific computing, simulation and modelling tools |
| 1. Homology Modeling 2. MD simulations 3. Quantum Chemistry | 1. Drug design 2. Computational chemistry 3. GPCR models |
| Gloriam, David University of Copenhagen | DK | WG3, WG5 | 1. Web and information systems, database systems 2. Theoretical and computational chemistry 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. open access databases 2. structure determination 3. ligand identification and optimisation | 1. Open access databases 2. Computational drug design 3. Structure determination |
| Carlsson, Jens Uppsala University Website | SE | WG3, WG4, WG5 | 1. Bioinformatics 2. Medicinal chemistry 3. Theoretical and computational chemistry |
| 1. Virtual screening (Molecular docking) 2. Molecular dynamics simulations 3. Homology modeling | 1. Polypharmacology/Selective/Biased ligands 2. Structural basis of GPCR activation 3. Accurate structural models of ALL GPCRs |
| Bennett, Kirstie Sosei Heptares Website | GB | WG3 | 1. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Cellular and Developmental Biology 3. Mathematics (applications in science and industry) |
| 1. GPCR 2. Molecular Pharmacology |
|
| Wessel Andressen, Kjetil University of Oslo Website | NO | WG1 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular mechanisms of signalling pathways 3. Macromolecular complexes |
| 1. FRET 2. biosensor cGMP 3. biosensors | 1. cGMP 2. 5-HT7 receptor 3. Cardiomyocyte |
| Lazar, Josef Institute of Organic Chemistry and Biochemistry CAS Website | CZ | WG1, WG2, WG3, WG4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Cell signalling and signal transduction 3. Spectroscopic and spectrometric techniques |
| 1. polarization microscopy 2. G protein signaling | 1. Cell signaling 2. Advanced optical microscopy 3. G proteins |
| Canals, Meritxell University of Nottingham | GB | WG1, WG2, WG3, WG4 | 1. Molecular mechanisms of signalling pathways 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Opioid receptors 2. GPCRs 3. Signalling |
|
| Radi, Marco University of Parma Website | IT | WG3 | 1. Medicinal chemistry 2. Method development in chemistry 3. Organic chemistry |
| 1. small molecules 2. docking 3. combinatorial chemistry | 1. CCR6 2. CXCR4 3. GPER-1 |
| Contino, Marialessandra University of Bari | IT | WG3, WG4 | 1. Biological chemistry 2. Molecular mechanisms of signalling pathways 3. Neurological disorders |
| 1. GPCRs 2. GPCRs 3. GPCRs | 1. GPCRs 2. Cancer 3. Neurodegeneration |
| Dubiel, Mariam Heinrich Heine University of Duesseldorf Website | DE | WG1 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Neurological disorders 3. Molecular mechanisms of signalling pathways |
| ||
| Chabbert, Marie CNRS | FR | WG1 | 1. Computational biology 2. Molecular mechanisms of signalling pathways 3. Bioinformatics |
| 1. GPCR 2. Biased Signaling 3. Molecular Simulations |
|
| Fardilha, Margarida University of Aveiro Website | PT | WG2, WG3 | 1. Biochemistry 2. Genetics, ’Omics’, Bioinformatics and Systems Biology 3. Physiology, Pathophysiology and Endocrinology |
| 1. Male reproduction 2. Sperm motility 3. Protein phosphatase 1 |
|
| Solano, Maria Marti University of Cambridge | UK | WG1, WG3 | 1. Molecular mechanisms of signalling pathways 2. Computational biology 3. Systems biology |
| 1. Pharmacogenomics 2. Signalling bias 3. Structural Biology |
|
| Corminboeuf, Olivier Idorsia Pharmaceuticals Ltd Website | FR | WG1, WG2, WG3, WG4 | 1. Medicinal chemistry 2. Immunological mechanisms in disease 3. Pharmacology and pharmacogenomics |
| 1. Medicinal Chemistry 2. Oncology 3. Immunology |
|
| D'Ursi, Pasqualina National Research Council Website | IT | WG1 | 1. Molecular architecture and structure 2. Bioinformatics 3. Medicinal chemistry |
| 1. Protein 2. Function 3. drug design | 1. Bionformatics 2. Protein structure activity 3. Drug design |
| Dr. Henri Xhaard University of Helsinki | FI | WG3, WG5 | 1. Molecular architecture and structure 2. Bioinformatics 3. Web and information systems, database systems |
| 1. Databases for sequence/structure analysis 2. Protein and protein-ligand complexes modeling 3. Virtual ligand screening and design | 1. Machine learning 2. Ligand design 3. Structural modeling |
| Kiec-Kononowicz Katarzyna Jagiellonian University | PL | wg3 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| 1. medicinal chemistry 2. GPCRs 3. drug-like properties |
|
| Kozielewicz Pawel Karolinska Institutet | SE | wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Biocomputing and molecular computation |
| 1. Receptors 2. signaling 3. molecular dynamics | 1. GPCRs 2. small ligands 3. drug discovery |
| Frank Philippe University of Tours | FR | wg1, wg2, wg3, wg4, wg5 | 1. Fundamental mechanisms underlying cancer 2. Lipid biology 3. Fundamental mechanisms underlying cardiovascular diseases |
| 1. Breast cancer model 2. Lipid metabolism 3. Lipid quantitification | 1. Breast Cancer 2. Cholesterol metabolism 3. Atherosclerosis |
| Leurs Rob Vrije Universiteit | false | wg1, wg2, wg3, wg4 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| 1. histamine receptors 2. chemokine receptors |
|
| Schiedel Anke University of Bonn | DE | wg1, wg2 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| 1. GPCR 2. signal transduction 3. protein protein interactions |
|
| Sposini Silvia CNRS | FR | wg1, wg2, wg3, wg4, wg5 | 1. Organelle biology and trafficking 2. Organelle biology and trafficking 3. Cell signalling and signal transduction |
| 1. TIRF microscopy 2. Receptor Signalling 3. Neuronal cultures | 1. GPCR 2. Membrane Trafficking 3. Endosomal signalling |
| Bradley Sophie University of Glasgow | GB | wg2, wg3 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. 1. Mathematics (applications in science and industry) |
| ||
| Garcia-Sosa Alfonso T. University of Tartu Website | EE | wg3, wg5 | 1. Theoretical and computational chemistry 2. Theoretical and computational chemistry 3. Medicinal chemistry |
| 1. drug design 2. drug discovery 3. molecular simulation |
|
| Tunaru Sorin Institute of Biochemistry, Romanian Academy | ES | wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Lipid biology |
| 1. orphan GPCR, drug discovery, assay development 2. lipolysis, pancreatic beta cells, insulin signaling 3. ligand purification, | 1. obesity 2. drug addiction 3. neurodegeneration |
| Uldrijan Stjepan Masaryk University Website | CZ | wg2, wg3 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Cell cycle, division and growth |
| 1. Cell signaling 2. ERK pathway 3. Melanoma |
|
| Murga, Cristina Universidad Autónoma de Madrid Website | ES | WG2, WG3 | 1. Cell signalling and signal transduction 2. Metabolism, biological basis of metabolism-related disorders 3. Organ physiology and pathophysiology |
| 1. Western Blot 2. Glucose and Insulin tolerance tests 3. Immunofluorescence | 1. Signalling 2. Pathophysiology 3. Metabolism |
| Kellenberger, Esther Université de Strasbourg Website | FR | WG3 | 1. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Medicinal chemistry 3. Scientific computing, simulation and modelling tools |
| 1. virtual screening 2. docking 3. pharmacophore | 1. Molecular recognition 2. Structure-activity relationship 3. G-protein coupled receptor |
| Nyagulova Kandemish, Emilia Bahçeşehir University Website | TR | WG2 | 1. Molecular mechanisms of signalling pathways 2. Non-coding RNAs 3. Cell signalling and signal transduction |
| 1. Cell culture 2. Gene expression 3. Protein expression | 1. Cell signaling 2. Cancer 3. Non-coding RNAs |
| Žerovnik, Eva Institute "Jožef Stefan" | SI | WG1, WG3, WG4, | 1. Physical chemistry of biological systems 2. Biological chemistry 3. Nanophysics |
| 1. CD, NMR 2. AFM, TEM, STED 3. Western blots, proteomics | 1. Protein folding 2. Protein aggregation 3. Cascade of neurodegeneration |
| Hamann, Jörg Amsterdam University Medical Centers | NL | WG2 | 1. Immunological mechanisms in disease 2. Regulation and effector functions of the immune response 3. Molecular mechanisms of signalling pathways |
| 1. Expression profiling 2. Zebrafish 3. Multiple sclerosis | 1. Adhesion GPCRs 2. Microglia 3. T cells |
| M Keseru, György Research Center for Natural Sciences Website | HU | WG3 | 1. Medicinal chemistry 2. Fundamental aspects of synthetic biology and chemical biology 3. Theoretical and computational chemistry |
| 1. Medicinal chemistry 2. Chemical biology 3. Drug design |
|
| Bermudez, Marcel Freie Universität Berlin Website | DE | WG1, WG3, WG5 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Medicinal chemistry 3. Molecular mechanisms of signalling pathways |
| 1. virtual screening 2. molecular dynamics 3. drug design | 1. GPCR pharmacology 2. Rational drug design 3. Signal tranduction |
| Capiod, Thierry Université Paris-Descartes Website | FR | WG2, WG3 | 1. Cellular and Developmental Biology 2. Physiology, Pathophysiology and Endocrinology 3. Immunity and Infection |
| 1. Prostate 2. Cancer 3. Calcium |
|
| Sommer, Martha ISAR Bioscience Website | DE | WG1, WG2 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Biochemistry |
| 1. Arrestin activation mechanism 2. Arrestin-GPCR interactions 3. Biological roles of arrestin |
|
| Stark, Holger Heinrich Heine University Düsseldorf Website | DE | WG1, WG2, WG3 | 1. Cell signalling and signal transduction 2. Glycomics/Lipidomics 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Drug design 2. GPCR screening 3. enzyme screening | 1. Medicinal Chemistry 2. Drug development 3. Neurotransmitter |
| Mordalski, Stefan Intomics A/S | DK | WG1, WG3 | 1. Molecular mechanisms of signalling pathways 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| ||
| Horvat Anemari University of Ljubljana, Faculty of Medicine | SI | wg1, wg2, wg3, wg4, wg5 | 1. Cell signalling and signal transduction 2. Cell signalling and signal transduction 3. Metabolism, biological basis of metabolism-related disorders |
| 1. Metabolism 2. cAMP and Ca2+ signaling 3. Neurodegeneration |
|
| Laurenzana Anna University of Florence | IT | wg2 | 1. Molecular mechanisms of signalling pathways 2. Molecular mechanisms of signalling pathways 3. Cell junctions, cell adhesion, cell communication and the extracellular matrix |
| 1. cell membrane receptors 2. protein immunoprecipitation 3. Xenograft models of human cancer | 1. cell biology 2. molecular biology 3. cancer |
| Markus Muttenthaler University of Vienna Website | AT | WG2, WG3, WG4, WG5 | 1. Biological chemistry 2. Medicinal chemistry 3. Pharmacology and pharmacogenomics |
| 1. Peptides 2. GPCRs and Ion channels | 1. Neuropeptides 2. Venoms to Drugs 3. Medicinal Chemistry |
| Thorsen Thor S. University of Copenhagen Website | DK | wg1, wg2, wg3 | 1. Molecular architecture and structure 2. Molecular architecture and structure 3. Physical chemistry of biological systems |
| 1. electron microscopy 2. drug design 3. signaling | 1. membrane proteins 2. drug design 3. structure determination |
| Namasivayam Vigneshwaran University of Bonn | DE | wg3, wg4, wg5 | 1. Artificial intelligence, intelligent systems, multi agent systems 2. Artificial intelligence, intelligent systems, multi agent systems 3. Theoretical and computational chemistry |
| ||
| Cong, Xiaojing Université Côte d'Azur | FR | WG1, WG2, WG3 | 1. Theoretical and computational chemistry 2. Physical chemistry of biological systems 3. Bioinformatics |
| ||
| Franziska Heydenreich University of Cambridge | UK | WG1, WG2 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Computational biology |
| 1. cell signalling 2. fluorescence 3. data science | 1. Signalling 2. Conformations |
| vischer henry Vrije Universiteit Amsterdam | NL | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Biological chemistry 3. Medicinal chemistry |
| ||
| Scarpa Miriam University of Glasgow | GB | wg2, wg3 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Neurological disorders |
| ||
| Schöneberg Torsten Leipzig University | DE | wg2, wg3 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Evolutionary genetics |
| ||
| Łażewska Dorota Jagiellonian University Medical College | PL | wg2, wg3 | 1. Medicinal chemistry 2. Medicinal chemistry 3. Organic chemistry |
| 1. synthesis of GPCR ligands 2. medicinal chemistry | 1. GPCR ligands 2. CNS disorders 3. drug synthesis |
| Esguerra Neira Mauricio University of Copenhagen | DK | wg1, wg5 | 1. Web and information systems, database systems 2. Molecular mechanisms of signalling pathways 3. Computational biology |
| 1. gpcr 2. knowledge based analysis 3. interaction networks and prediction |
|
| Chevillard Florent Idorsia Pharmaceuticals Ltd | CH | wg3, wg4, wg5 | 1. Theoretical and computational chemistry 2. Machine learning 3. Bioinformatics |
| 1. Fragment 2. GPCR 3. Modeling |
|
| Doğan Berna Bahcesehir University | TR | wg1, wg2, wg3, wg4 | 1. Physical chemistry 2. Theoretical and computational chemistry 3. Machine learning |
| ||
| Gentry Patrick University of Copenhagen | DK | wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular mechanisms of signalling pathways 3. Medicinal chemistry |
| 1. GPCR 2. Medicinal Chemistry | 1. GPCR 2. Orphan receptors 3. Allosteric modulators |
| O'Brien Shannon University of Birmingham | GB | wg1, wg2 | 1. Molecular mechanisms of signalling pathways 2. Metabolism, biological basis of metabolism-related disorders 3. Molecular aspects of endocrinology |
| 1. G protein-coupled receptors 2. cell signalling 3. protein-protein interactions |
|
| Gabrielsen Mari UiT Arctic University of Norway | NO | wg3 | 1. Theoretical and computational chemistry 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Psychiatric disorders |
| 1. GPCRs 2. Molecular modelling 3. Pharmacology |
|
| Russotto Clizia UiT - Arctic University of Norway | NO | wg1, wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Scientific computing, simulation and modelling tools 3. Imaging for medical diagnosis |
| 1. molecular modelling | 1. P.E.T. radioactive tracers 2. GnR-Hr 3. Glioblastoma |
| Koszegi Zsombor University of Birmingham | GB | wg1 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| 1. single-molecule 2. microscopy | 1. single-molecule 2. TIRF 3. GPCR |
| Middleton Daniel University of Copenhagen | DK | wg1, wg3, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Molecular mechanisms of signalling pathways 3. Macromolecular complexes |
| ||
| Lanoiselée Yann University of Birmingham | GB | wg1, wg2, wg3, wg4 | 1. 1. Mathematics (applications in science and industry) 2. Statistical physics 3. Physics of biological systems |
| 1. diffusion 2. complex systems 3. inverse problems |
|
| Zarzycka Barbara Vrije Universiteit Amsterdam | NL | wg3, wg4, wg5 | 1. Scientific computing, simulation and modelling tools 2. Scientific computing, simulation and modelling tools 3. Molecular architecture and structure |
| 1. computer-aided drug design 2. molecular modulators 3. medicinal chemistry |
|
| Andric Silvana Faculty of Sciences, University of Novi Sad | RS | wg2 | 1. Cell signalling and signal transduction 2. Molecular aspects of endocrinology 3. Molecular mechanisms of signalling pathways |
| ||
| Bećin Alisa University of Novi Sad (UNS) | RS | wg2 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Molecular aspects of endocrinology |
| 1. Transcriptomic analysis 2. Photometric analysis 3. Immuno assays | 1. Chronobiology 2. Stress 3. Leydig cells |
| Radovic Pletikosic Sava University of Novi Sad | RS | wg2 | 1. Molecular aspects of endocrinology 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| 1. knockout mice 2. RNA/DNA/protein manipulation and analyses 3. enzyme immunoassays | 1. mitochondrial dynamics 2. steroidogenesis 3. insulin and IGF1 receptors |
| Marinković Dijana University of Novi Sad, Serbia | RS | wg2 | 1. Cell signalling and signal transduction 2. Molecular aspects of endocrinology 3. Molecular mechanisms of signalling pathways |
| 1. DNA/RNA/protein manipulation | 1. Chronobiology 2. Leydig cells |
| Miljus Tamara University of Birmingham | GB | wg1, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Biochemistry |
| 1. GPCRs 2. biased signalling 3. molecular basis of GPCR signalling |
|
| Harwood Clare University of Nottingham | GB | wg1 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. molecular efficacy 2. single molecule pharmacology |
|
| Ambriović-Ristov Andreja Ruđer Bošković Institute | HR | wg1, wg2 | 1. Cell junctions, cell adhesion, cell communication and the extracellular matrix 2. Cytoskeleton and cell behaviour 3. Molecular mechanisms of signalling pathways |
| 1. adhesome analysis using proteomics 2. in vitro cell migration and invasion 3. immunofluorescence | 1. integrin adhesion complexes 2. cancer 3. crosstalk between GPCRs and integrins |
| Hanson Julien University of Liège | BE | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Organ physiology and pathophysiology 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Complementation assay 2. BRET 3. GPCR | 1. orphan GPCR 2. Endocrinology 3. Metabolism |
| Rovira Xavier Medicinal Chemistry & Synthesis group Institute for Advanced Chemistry of Catalonia (IQAC) Spanish National Research Council (CSIC) | ES | wg1, wg3, wg5 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Medicinal chemistry 3. Photochemistry |
| 1. Molecular pharmacology 2. Receptor signalling 3. Ligand-receptor interactions | 1. Photopharmacology 2. GPCR 3. Bias Signalling |
| Brünle Steffen Paul Scherrer Institute | CH | wg1, wg2, wg3, wg4, wg5 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| 1. Protein X-ray Crystallography, Cryo-EM 2. Time-resolved X-ray crystallography 3. GPCR Signal Transduction | 1. Structural Biology on GPCRs 2. Allosteric Modulation of GPCRs 3. Drug-discovery |
| Autore Flavia Sosei-Heptares | CH | wg1, wg2, wg3, wg4, wg5 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. Biochemistry |
| ||
| Minos Matsoukas University of Patras | GR | wg1, wg3 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Biocomputing and molecular computation 3. Bioinformatics |
| ||
| Maiju Rinne University of Helsinki | FI | wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. Medicinal chemistry |
| 1. Drug discovery 2. Structure modeling 3. Signaling pathways | 1. GPCR evolution 2. Orexin system 3. Structural modeling |
| Christoffer K. Goth University of Copenhagen | DK | wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Glycobiology |
| 1. Chemokine receptors 2. Post translation modifications 3. Biased signaling |
|
| Rebeca Diez-Alarcia University of the Basque Country UPV/EHU Website | ES | wg1, wg2, wg3 | 1. Neural cell function, communication and signalling, neurotransmission 2. Psychiatric disorders 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Neuropyschopharmacology 2. GPCR 3. Cell signaling |
|
| Jesús Giraldo Universitat Autònoma de Barcelona Website | ES | wg1, wg2, wg3 | 1. Biocomputing and molecular computation 2. Molecular mechanisms of signalling pathways 3. Biological chemistry |
| 1. GPCR allostery and dynamics 2. Quantitative pharmacology 3. Drug design | 1. GPCR oligomerization 2. GPCR allostery 3. GPCR dynamics |
| Linda Johansson University of Gothenburg | SE | wg1, wg2, wg3 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Molecular mechanisms of signalling pathways 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Crystallography 2. Cryo-EM 3. Signaling assays | 1. Structural determination of GPCRs 2. GPCR dimerization 3. Orphan GPCRs |
| Jacopo Tricomi University of Florence | IT | wg1 | 1. Organic chemistry 2. Glycobiology 3. Biological chemistry |
| ||
| AYDIN Banu Marmara University School of Medicine | TR | wg2, wg3 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| 1. Cell culture 2. Signal transduction cascades 3. RNA, DNA expression | 1. cell signaling 2. cell proliferation 3. cancer molecular biology |
| Christa Müller University of Bonn Website | DE | wg1, wg2, wg3,wg4 | 1. Medicinal chemistry 2. Biological chemistry 3. Cell signalling and signal transduction |
| 1. Drug development 2. GPCRs and ectonucleotidases 3. Purinergic signaling | 1. Purines and their membrane targets 2. Orphan GPCRs 3. Ectonucleotidases |
| Szalai Bence Semmelweis University | HU | wg1, wg2 | 1. Systems biology 2. Computational biology 3. Transcriptomics |
| 1. perturbation transcriptomics 2. cancer drug sensitivity 3. machine learning | 1. perturbation gene expression profiles 2. role in GPCRs in cancer 3. drug repurposing |
| Georgi Kanev InterAx | CH | wg1, wg4 | 1. Artificial intelligence, intelligent systems, multi agent systems 2. Bioinformatics 3. Structural biology and its methodologies |
| 1. Machine learning 2. Ligand binding 3. Cheminformatics | 1. Deep learning 2. Virtual screening 3. ADRB2 |
| Marta Busnelli CNR | IT | wg1, wg2, wg3 | 1. Cell signalling and signal transduction 2. Biological chemistry 3. Neural cell function, communication and signalling, neurotransmission |
| 1. oxytocin/vasopressin receptor 2. functional selective agonists 3. cell signalling |
|
| Belgin BUYUKAKILLI Mersin University | TR | wg2 | 1. Physics of biological systems 2. Neural cell function, communication and signalling, neurotransmission 3. Neurological disorders |
| 1. Neurobiopyhsics 2. ischemia-reperfusion, alzheimer 3. Cell biophysic | 1. Motor dysfunction 2. Neuropathy 3. Hypoxic-ischemic injury |
| Maxime Louet Université de Montpellier | FR | wg1, wg3 | 1. Molecular architecture and structure 2. Theoretical and computational chemistry 3. Physics of biological systems |
| 1. Molecular Modeling 2. Membrane protein structure 3. Conformational ensemble | 1. GPCR 2. protein-protein interactions 3. protein motions |
| Nicolas Floquet Centre National de la Recherche Scientifique (CNRS) | FR | wg1, wg3 | 1. Molecular architecture and structure 2. Theoretical and computational chemistry 3. Physics of biological systems |
| 1. Molecular Dynamics Simulations 2. Analysis of Structures 3. Conformational ensembles | 1. GPCR 2. protein-protein interactions 3. ligand design and selectivity |
| Bernard Masri Institut Cochin - INSERM U1016 | FR | wg1, wg3 | 1. Molecular aspects of endocrinology 2. Fundamental mechanisms underlying cancer 3. Fundamental mechanisms underlying cardiovascular diseases |
| 1. Resonance Energy Transfer | 1. GPCR 2. Signaling 3. Cancer |
| Rita Melo Instituto Superior Tecnico | PT | wg1, wg3, wg4,wg5 | 1. Theoretical and computational chemistry 2. Computational biology 3. Machine learning |
| 1. drug design 2. protein-protein interface 3. machine learning | 1. molecular modeling 2. protein-protein interface 3. machine learning |
| Necla Birgül Bogazici University | TR | wg2 | 1. Molecular genetics, reverse genetics, forward genetics, genome editing 2. Computational biology 3. Cell signalling and signal transduction |
| 1. Cell culture 2. Molecular Dynamic and Simulation 3. Knock-out | 1. Deorphanising GPCRs 2. CRISPR/Cas9 technology 3. Purification of ligands |
| Nuska Tschammer Crelux, a WuXi AppTec Company | DE | wg4 | 1. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Medicinal chemistry 3. Pharmacology and pharmacogenomics |
| 1. MicroScale Thermophoresis 2. FRET | 1. Target-to-hit 2. DNA encoded libraries 3. Fragment screening |
| Claudia Stäubert Leipzig University, Medical Faculty | DE | wg1, wg2, | 1. Cell signalling and signal transduction 2. Biochemistry 3. Molecular mechanisms of signalling pathways |
| 1. Metabolism 2. GPCR | 1. GPCR 2. Signaling, trafficking 3. Evolution, metabolism |
| Lucie Pellissier PRC UMR INRAE CNRS university of Tours | FR | wg1, wg2, wg3,wg4 | 1. Pharmacology and pharmacogenomics 2. Psychiatric disorders 3. Neuronal development, plasticity and regeneration |
| 1. RNAseq 2. BRET | 1. Autism 2. Oxytocin |
| Desislava Nesheva University of Nottingham | UK | wg3 | 1. Pharmacology and pharmacogenomics 2. Regulation and effector functions of the immune response 3. Medicinal chemistry |
| 1. In vitro signalling assay, ligand binding in vitro 2. Cell culture, molecular cloning 3. ELISA | 1. GPCR pharmacology 2. Cell signalling 3. Chemokines |
| Mr. Jack Lochray University of Nottingham | UK | wg1, wg2, wg3, wg4, wg5 | 1. Cell signalling and signal transduction 2. Molecular biophysics 3. Biological chemistry |
| ||
| Dr. Laura Humphrys Universität Regensburg | DE | wg1, wg2, wg3, wg4, wg5 | 1. Cellular and Developmental Biology 2. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. Neuroscience and Neural Disorders |
| 1. GPCR | |
| Dr. Biljana Stankovic Institute of molecular genetics and genetic engineering University of Belgrade | RS | wg5 | 1. Bioinformatics 2. Biostatistics 3. Genomics |
| 1. Programming 2. Functional genomics 3. Drug-gene interactions | 1. Bioinformatics 2. Pharmacogenomics 3. Biomedicine |
| Dr. Nikola Kotur Institute of Molecular Genetics and Genetic Engineering | RS | wg5 | 1. Genetics, ’Omics’, Bioinformatics and Systems Biology |
| ||
| Mr. Leonhard Schink Biotechnologie Institut Thurgau an der Universität Konstanz Website | DE | wg1, wg2, wg3, wg4, wg5 | 1. Organelle biology and trafficking 2. Molecular mechanisms of signalling pathways 3. Adaptive immunity |
| ||
| Bradley Hoare University of Nottingham | UK | wg1, wg2, wg3, wg4 | 1. Biochemistry 2. Cell signalling and signal transduction 3. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions |
| ||
| Ms. Nicola Dijon University of Nottingham | UK | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Mathematics 3. Mathematics |
| ||
| Christoph Matti University College London | UK | wg1, wg2, wg4 | 1. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Cellular and Developmental Biology 3. Immunity and Infection |
| 1. Confocal Micrscopy 2. BRET 3. Protein production and cellular assays |
|
| Lisa Forster University of Regensburg | DE | wg1, wg2, wg3, wg4,wg5 | 1. Medicinal chemistry 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| 1. Assay development 2. Unraveling of signalling pathways |
|
| Graeme Milligan University of Glasgow | UK | wg1, wg4 | 1. Mathematics 2. Mathematics 3. Mathematics |
| ||
| Atakan Aydin Max-Delbrück-Center | DE | wg2 | 1. Biological chemistry 2. Medicinal chemistry 3. Systems biology |
| ||
| Pawel Krawinski Trinity College Dublin | IE | wg1, wg4 | 1. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Biochemistry |
| ||
| Nicoli Alessandro Leibniz-Institut für Lebensmittel-Systembiologie an der Technischen Universität München | DE | wg4 | 1. Theoretical and computational chemistry 2. Molecular architecture and structure 3. 1. Mathematics (applications in science and industry) |
| 1. MD, Homology Modelling | |
| Schulte Gunnar Karolinska Institute | SE | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. WNT 2. Frizzled 3. GPCR |
|
| Casajuana-Martin Nil Universitat Autonoma Barcelona | ES | wg1, wg3 | 1. Bioinformatics 2. Scientific computing, simulation and modelling tools 3. Molecular mechanisms of signalling pathways |
| 1. Molecular dynamics 2. Homology modeling 3. Data analysis | 1. GPCR activation 2. Molecular simulations 3. GPCR Oligomerization |
| Sykes David University of Nottingham | GB | wg1, wg2, wg3, wg4 | 1. 7. Physiology, Pathophysiology and Endocrinology 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. 8. Neuroscience and Neural Disorders |
| 1. GPCRs 2. Cell Signalling 3. FRET & BRET | 1. GPCRs 2. Cell SIgnalling 3. Biophysical techniques |
| Milicevic Jelena Vinča Institute of Nuclear Sciences | RS | wg3 | 1. Organic chemistry 2. Medicinal chemistry 3. Physical chemistry |
| ||
| Honkisz-Orzechowska Ewelina Jagiellonian University | PL | wg1, wg2, wg3, wg4, wg5 | 1. Molecular mechanisms of signalling pathways 2. Morphology and functional imaging of cells and tissues 3. Neurological disorders |
| 1. neuroprotection 2. GPR18 3. autophagy |
|
| Holliday Nicholas University of Nottingham | GB | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. GPCR signalling 2. kinetics 3. molecular pharmacology |
|
| Mega Tiber Pinar Marmara University, School of Medicine | TR | wg1, wg2, wg3 | 1. Cell signalling and signal transduction 2. Cell death (including senescence) and autophagy 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Cell culture and apoptosis assay 2. Western Blotting 3. in vitro assays | 1. Cell signaling and signal transduction 2. Cell death |
| Mokrosinski Jacek University of Cambridge | GB | wg1, wg2 | 1. Molecular mechanisms of signalling pathways 2. Metabolism, biological basis of metabolism-related disorders 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| ||
| Brocos-Mosquera Iria University of the Basque Country | ES | wg1, wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology 3. 8. Neuroscience and Neural Disorders |
| ||
| Ulven Trond University of Copenhagen | DK | wg3 | 1. Medicinal chemistry 2. Lipid biology 3. Organic chemistry |
| ||
| Llinas del Torrent Claudia Universitat Autonoma Barcelona | ES | wg1, wg2, wg3, wg5 | 1. Bioinformatics 2. Macromolecular complexes 3. Molecular mechanisms of signalling pathways |
| ||
| Jiménez-Rosés Mireia University of Nottingham | GB | wg1, wg3, wg4 | 1. Scientific computing, simulation and modelling tools 2. Bioinformatics 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Molecular dynamic simulations 2. Virtual screening 3. Structure-Based Drug Discovery | |
| Cunningham Margaret University of Strathclyde | UK | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Fundamental mechanisms underlying cardiovascular diseases 3. Cell signalling and signal transduction |
| 1. Pharmacology 2. Receptor trafficking 3. Protein-protein interaction techniques | 1. Cardiovascular GPCRs |
| Gustavsson Martin University of Copenhagen | DK | wg1, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Macromolecular complexes 3. Molecular mechanisms of signalling pathways |
| 1. Crystallography 2. Binding and signaling assays 3. NMR | 1. Receptor structure and dynamics 2. Receptor:ligand interactions 3. Chemokine receptors |
| Hesse Sarah University of Glasgow | GB | wg2, wg3, wg5 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Neurological disorders 3. Molecular mechanisms of signalling pathways |
| 1. M1 muscarinic receptor 2. ligand in vitro characterisation 3. Alzheimer disease models | 1. Drug studies 2. Microscopy 3. Animal Models |
| Eckel Juergen Center of Competence for Innovative Diabetes Therapy - KomIT | DE | wg2, wg3 | 1. 7. Physiology, Pathophysiology and Endocrinology 2. 10. Applied Medical Technologies, Diagnostics, Therapies and Public Health 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. Physiology of signal transduction 2. Diabetes and metabolic syndrome 3. Drug development |
|
| Stoeger Verena | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular genetics, reverse genetics, forward genetics, genome editing 3. Molecular aspects of endocrinology |
| 1. CRISPR/Cas9, stable/transient transfections, ddPCR 2. ELISA, FACS, IHC, Western Blot 3. human intervention studies, organ tissue bath, homolgy modelling, docking | 1. signal transduction peripheral taste & odor receptors 2. functional role of the peripheral sensory system |
|
| Granier Sebastien INSERM | FR | wg1, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Molecular mechanisms of signalling pathways 3. Macromolecular complexes |
| ||
| Ardévol Anna Universitat Rovira i Virgili | ES | wg2, wg3 | 1. Food sciences 2. Metabolism, biological basis of metabolism-related disorders 3. Molecular aspects of endocrinology |
| 1. Enterohormones 2. Rat 3. Ussing chamber | 1. Ecnomotopic Taste receptors 2. Gastrointestinal tract 3. Enterohormone secretion |
| Rodríguez Gallego Esther Universitat Rovita i Virgili | ES | wg2, wg3, wg4 | 1. Biochemistry 2. Molecular mechanisms of signalling pathways 3. Metabolism, biological basis of metabolism-related disorders |
| 1. western blot 2. electron microscopy 3. nutritional studies | 1. metabolism 2. autophagy 3. biomarkers discovery |
| Oz Arslan Devrim Acibadem University | TR | wg1, wg2 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Molecular mechanisms of signalling pathways 3. Cell signalling and signal transduction |
| 1. Cellular imaging 2. Western blot 3. Protein interaction | 1. Cellular signalling mechanisms 2. Autophagy 3. Mitochondrial dynamics |
| Allikalt Anni FAU Erlangen-Nürnberg | DE | wg1, wg3, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Medicinal chemistry 3. Neurological disorders |
| 1. Ligand binding assays 2. Protein expression and purification 3. Novel compounds | 1. Structural biology 2. Structure based design 3. Novel methods |
| Peach Chloe Centre of Membrane Proteins and Receptors, University of Nottingham | GB | wg1, wg2, wg4 | 1. Molecular mechanisms of signalling pathways 2. 6. Cellular and Developmental Biology 3. 7. Physiology, Pathophysiology and Endocrinology |
| 1. Receptor Tyrosine Kinases 2. G Protein-Coupled Receptors 3. Spatiotemporal Dynamics |
|
| Arrate Itziar Unibersity of the Basque Country | ES | wg1, wg2, wg3 | 1. Cell cycle, division and growth 2. Psychiatric disorders 3. Neural cell function, communication and signalling, neurotransmission |
| 1. gprc 2. Biased agonism 3. serotonin 2A receptor |
|
| Ullrich Annika Friedriach-Alexanderuniversuität Erlangen-Nürnberg | DE | wg1, wg3 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| 1. structure determination 2. interactions 3. signaling pathway |
|
| Navarro Brugal Gemma University of Barcelona | ES | wg1, wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Biochemistry 3. Molecular mechanisms of signalling pathways |
| 1. GPCR 2. Drug adiction 3. neurodegeneration |
|
| Rivas Santisteban Rafael Universitat de Barcelona | ES | wg1 | 1. Macromolecular complexes 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| ||
| Lillo Jové Jaume Universitat de Barcelona | ES | wg1 | 1. Macromolecular complexes 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| ||
| Lillo Marquez Alejandro University of Barcelona | ES | wg1, wg2, wg3 | 1. Neurological disorders 2. Immunological mechanisms in disease 3. Molecular mechanisms of signalling pathways |
| 1. Neuroscience 2. Neurodegeneration 3. Autoimmunity |
|
| JEAN-ALPHONSE Frederic CNRS-INRAE | FR | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Molecular aspects of endocrinology |
| 1. cAMP 2. Imaging 3. biased ligands | 1. GPCR 2. Endosomes 3. Gonadotropins |
| Orun Oya Marmara University School of Medicine | TR | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Quantitative genetics 3. Cell signalling and signal transduction |
| 1. recombinant DNA tech, cloning 2. protein purification, FRET 3. gene and protein quantification methods | 1. molecular biology of cancer 2. genetic regulations 3. cell signaling |
| Cecon Erika Istitut Cochin, CNRS, INSERM, Université de Paris | FR | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Metabolism, biological basis of metabolism-related disorders |
| ||
| Ding Tianyi Queen's University of Belfast | GB | wg1, wg2, wg3, wg4, wg5 | 1. Macromolecular chemistry 2. Molecular architecture and structure 3. 2. Physics and Chemistry |
| ||
| Casanovas Ferrero Mireia University of Barcelona | ES | wg1, wg2, wg3 | 1. Biochemistry 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Neurological disorders |
| 1. GPCR 2. addiction |
|
| Ben Shoshan-Galeczki Yaron Hebrew university of Jerusalem | IL | wg1, wg3, wg4 | 1. Food sciences 2. Bioinformatics 3. Biochemistry |
| 1. Docking 2. Modeling 3. Sugars | 1. Sweet taste receptor 2. Docking 3. MD |
| Decker Michael Universität Würzburg | DE | wg3 | 1. Medicinal chemistry 2. Neurological disorders 3. Organic chemistry |
| 1. organic 2. in vitro | 1. Alzheimer's disease 2. Photopharmacology 3. Hybrid molecules |
| Schmidt Esther Boehringer Ingelheim Pharma GmbH & Co KG | DE | wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Psychiatric disorders 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. label-free holistic cell analysis 2. high throughput screening 3. MALDI-based binding assays for membrane proteins | 1. orphan GPCRs 2. immunology 3. psychiatric disorders |
| Steinmüller Sophie Julius-Maximilians-Universität Würzburg | DE | wg3 | 1. Medicinal chemistry 2. Photochemistry 3. Neurological disorders |
| 1. Synthesis 2. Photochemical GPCR ligand switches 3. In vitro assays (CB Receptors) | 1. Cannabinoid Ligands 2. Pharmacology / Molecular mechanisms of signalling pathways 3. Photochemistry |
| Sink Alexandra Julius-Maximilians-Universität Würzburg | DE | wg3 | 1. Medicinal chemistry 2. Organic chemistry 3. Photochemistry |
| 1. Synthesis 2. Ligand design 3. Photochemical switches | 1. Pharmacology 2. Molecular mechanism of signalling pathways 3. Cardiovascular disease |
| Spatz Philipp Julius-Maximilians-University Würzburg | DE | wg1, wg2, wg3 | 1. Medicinal chemistry 2. Organic chemistry 3. Neurological disorders |
| 1. Ligand design 2. fluorine incorporation 3. linkage and merge of pharmacophores | 1. Tracer development (PET) 2. AD treatment |
| Gerwe Hubert Universität Würzburg | DE | wg2, wg3, wg4 | 1. Medicinal chemistry 2. Organic chemistry 3. Photochemistry |
| 1. Ligand Design and Synthesis 2. Photochemical Switches 3. Photopharmacology | 1. GPCR Dynamics 2. Photochemistry of GPCR Ligands 3. Cardiovascular Diseases |
| Tutov Anna Julius-Maximilians-Universität Würzburg | DE | wg3 | 1. Medicinal chemistry 2. Organic chemistry 3. Molecular mechanisms of signalling pathways |
| 1. Synthesis 2. Organic Chemistry 3. in vitro assays | 1. Cannabinoid Receptors 2. Muscarinic Receptor M1 3. Positron Emission Tomography |
| Shekhani Rawan Karolinska Institutet | SE | wg1, wg2, wg3, wg4 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Kukkonen Jyrki University of Helsinki | FI | wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Scientific computing, simulation and modelling tools |
| 1. Binding and concentration response analyses 2. Interaction of the pathways | 1. GPCR signalling and pharmacology 2. Lipid messengers 3. orexins |
| VANDERMOERE Franck CNRS | FR | wg1, wg2, wg4 | 1. Proteomics 2. Molecular mechanisms of signalling pathways 3. Bioinformatics |
| 1. Mass spectrometry 2. Phosphoproteomics 3. Interactomics | 1. GPCRs 2. Proteomics 3. Signaling |
| Evenseth Linn S.M. Philipps-Universität Marburg | DE | wg1, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular mechanisms of signalling pathways 3. Scientific computing, simulation and modelling tools |
| 1. Virtual screening 2. Molecular Dynamics | |
| Wang Ziming Max-Delbruck-Center for Molecular Medicine | DE | wg1, wg2, wg3, wg4, wg5 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Cell junctions, cell adhesion, cell communication and the extracellular matrix 3. Molecular mechanisms of signalling pathways |
| ||
| Rabe Philipp University Leipzig | DE | wg1, wg2 | 1. Biochemistry 2. Molecular mechanisms of signalling pathways 3. Cell signalling and signal transduction |
| 2. Signal transduction | 1. Cancer 2. Signal transduction 3. Subcellular localization |
| Klenk Christoph University of Zurich | CH | wg1, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Macromolecular complexes 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Directed evolution 2. Ligand binding 3. X-ray crystallography | 1. Class B GPCRs 2. Structure-function mechanisms 3. Drug development |
| Olgac Abdurrahman Gazi University Faculty of Pharmacy | TR | wg1, wg3, wg5 | 1. Medicinal chemistry 2. Biocomputing and molecular computation 3. Molecular mechanisms of signalling pathways |
| 1. Medicinal Chemistry 2. Computer Aided Drug Design 3. Regulation of Dimerization | 1. Leukotrienes 2. GPCRs 3. Prostaglandins |
| Giorgino Toni CNR | IT | wg4, wg5 | 1. Computational biology 2. Physics of biological systems 3. Macromolecular chemistry |
| 1. Molecular dynamics 2. Biostatistics 3. Data mining | 1. Molecular dynamics 2. Biostatistics 3. Data mining |
| Latek Dorota University of Warsaw | PL | wg1, wg5 | 1. Computational biology 2. Molecular architecture and structure 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. integrative structural biology 2. molecular dynamics 3. drug discovery |
|
| durer zeynep Acibadem MAA University | TR | wg1, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Proteomics 3. Cytoskeleton and cell behaviour |
| 1. Adhesion proteins 2. Actin cytoskeleton and binding proteins 3. Conformational dynamics of proteins |
|
| Shapiro Tuchman Ziva University of Haifa | IL | wg1, wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Pamula Filip ETH | CH | wg1, wg2, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Macromolecular complexes 3. Biocomputing and molecular computation |
| 1. Membrane protein 2. cryo-EM 3. Spectroscopy | 1. Membrane biology 2. GPCR 3. Molecular machines |
| Umbach Simon Goethe Universität Frankfurt | DE | wg1, wg2, wg3, wg4, wg5 | 1. Biochemistry 2. Protein synthesis, modification, turnover 3. Fundamental aspects of synthetic biology and chemical biology |
| 1. Protein-Ligand Interaction 3. Cell-free protein synthesis | |
| Lemel Laura University of Nottingham | GB | wg2 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Cell biology 2. Pharmacology |
|
| Budvytyte Rima vilnius UNIVERSITY | LT | wg4 | 1. Physical chemistry of biological systems 2. Biochemistry 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. electrochemical impedance spectroscopy 2. Atomic force microscopyc 3. surface plasmon resonance | 1. lipid membrane 2. channels 3. protein-lipid interactions |
| Chavez Abiega Sergei University of Amsterdam | NL | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Bioinformatics |
| ||
| Schneider Johannes Friedrich-Alexander Universität Erlangen-Nürnberg | DE | wg1, wg2, wg3, wg4 | 1. Medicinal chemistry 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| 1. Functional Selectivity 2. Novel biased ligands 3. GPCR dynamics |
|
| DAM Julie University Paris Descartes , INSERM, CNRS | FR | wg1, wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular mechanisms of signalling pathways 3. Metabolism, biological basis of metabolism-related disorders |
| 1. GPCR 2. Leptin receptor 3. energy transfer technologies |
|
| lin jerry wmu | wg1, wg2, wg3, wg4, wg5 | 1. Theoretical and computational chemistry 2. Theoretical and computational chemistry 3. Theoretical and computational chemistry |
| |||
| Deganutti Giuseppe Coventry University | GB | wg1, wg3, wg4, wg5 | 1. Scientific computing, simulation and modelling tools 2. Theoretical and computational chemistry 3. Macromolecular complexes |
| 1. simulations 2. chemistry 3. biology | 1. Atomistic simulations 2. Non-equilibrium simulations 3. Drug design |
| Majellaro Maria University of Santiago de Compostela | ES | wg3 | 1. Organic chemistry 2. Medicinal chemistry 3. Method development in chemistry |
| 1. medicinal chemistry | 1. Synthesis of GPCR ligands 2. multicomponent reactions |
| Carofiglio Francesca Università degli Studi di Bari "Aldo Moro" | IT | wg3 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Baloglu Emel Acibadem Mehmet Ali Aydinlar University | TR | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. drug development, ligand classification 2. treatment 3. cellular signaling | 1. GPCR signaling 2. lung 3. heart |
| Guseinov Abdul-Akim Queen's University Belfast, School of Pharmacy | GB | wg1, wg3, wg4 | 1. Medicinal chemistry 2. Scientific computing, simulation and modelling tools 3. Macromolecular complexes |
| 1. Molecular modelling in drug design 2. Pharmacological assays 3. Organic Synthesis | 1. Molecular modelling 2. Computer-aided drug design 3. Pharmacological assays |
| Kooistra Albert University of Copenhagen | DK | wg1, wg5 | 1. Computational biology 2. Web and information systems, database systems 3. Bioinformatics |
| 1. Cheminformatics, database development, and predictive modeling 2. Structural bioinformatics 3. Structure-based drug design and optimization | 1. Cheminformatics, database development, and predictive modeling 2. Structure-based drug design and optimization 3. (Structural) bioinformatics |
| Morales Paula Spanish National Research Council | ES | wg3, wg5 | 1. Medicinal chemistry 2. Molecular architecture and structure 3. Biological chemistry |
| 1. Molecular modeling 2. Synthesis 3. Protein NMR | 1. Cannabinoid receptors 2. orphan GPCRs 3. Endocannabinoid signaling |
| Vila Julià Guillem Polytechnic University of Barcelona | ES | wg4 | 1. 3. Computer Science and Informatics 2. Scientific computing, simulation and modelling tools 3. Bioinformatics |
| ||
| Veerman Ben University of Strathclyde | GB | wg1, wg2, wg3, wg4, wg5 | 1. Fundamental mechanisms underlying cardiovascular diseases 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| 1. Connexin-43 2. PAR-1 3. Doxorubicin | 1. Cardiovascular 2. Toxicity 3. Exosomes |
| Jasko Piotr | PL | wg1, wg2, wg3, wg4 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular mechanisms of signalling pathways 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Radioligand binding assays 2. Cell-based assays 3. NMR | 1. GPCRs 2. Protein structure and dynamics 3. Cell signaling pathways |
| Hoxha Malvina Catholic University Our Lady of Good Counsel | AL | wg5 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Fundamental mechanisms underlying cardiovascular diseases 3. Epidemiology and public health |
| 1. Pharmacology 2. Pharmacotherapy |
|
| Castro Marián University of Santiago de Compostela | ES | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Psychiatric disorders |
| 1. GPCR ligand binding and signalling 2. FRET/BRET 3. in vitro/cell-based assays and HTS | 1. binding kinetics, ligand bias 2. signal compartmentalization 3. allosterism, early drug discovery |
| Kolocouris Antonios National and Kapodistrian University of Athenss | GR | wg3 | 1. Medicinal chemistry 2. Scientific computing, simulation and modelling tools 3. Organic chemistry |
| 1. computer aided drug design, computational organic chemistry, synthesis of drug molecules 2. MD simulations, binding free energy calculations, DFT calculations 3. NMR, SAXS, DSC | 1. computational design of adenosine receptor binders, MmpL3 transporter inhibitors against TB, influenza A M2 modulation M2 , P2X7 binders 2. Protein - lipid interactions 3. DFT calculations of weak hydrogen bonding and DFT-based mechanistic organic chemistry |
| Gupta Shailendra University of Rostock | DE | wg1, wg2, wg3, wg5 | 1. Scientific computing, simulation and modelling tools 2. Systems biology 3. Immunological mechanisms in disease |
| 1. Mathematical modeling 2. Pharmacophore modeling 3. Docking and simulation | 1. Disease maps 2. GPCRs 3. Drug repositioning |
| PONIMASKIN EVGENI Hanover Medical School | DE | wg1, wg4 | 1. Neural cell function, communication and signalling, neurotransmission 2. Neuronal development, plasticity and regeneration 3. Fundamental mechanisms underlying ageing |
| 1. quantitative molecular microscopy 2. FRET 3. high-troughput screening | 1. GPCR-mediated signaling 2. protein-protein interaction 3. post-translational protein modifications |
| Healey Robert IGF, Univ. Montpellier, CNRS, INSERM | FR | wg1, wg2, wg3 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Lipid biology |
| 1. Crystallography 2. Protein purification 3. HTS ligand discovery | 1. Membrane proteins 2. Drug discovery 3. Structural biology |
| Floquet Nicolas Centre National de la Recherche Scientifique (CNRS), Université de Montpellier | FR | wg1 | 1. Scientific computing, simulation and modelling tools 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Molecular Dynamics Simulations | 1. GPCRs coupling to modulators 2. Molecular simulations 3. Structural features of selectivity |
| Severo Gomes Antoniel Augusto Université de Montpellier | FR | wg1 | 1. Scientific computing, simulation and modelling tools 2. Macromolecular complexes 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Molecular Modelling 2. Molecular Dynamics 3. Normal Modes | 1. Protein Function 2. Biomolecular Interactions 3. Molecular Modelling |
| Lockington Hannah University of Nottingham | GB | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| ||
| Guthrie Brian Cargill | BE | wg1, wg2, wg3, wg4 | 1. Physics of biological systems 2. Physical chemistry of biological systems 3. Chemical physics |
| 1. GPCR signal transduction 2. Class-C 3. Class-A |
|
| Hoffmann Carsten University Hospital Jena | DE | wg1, wg2, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Molecular Pharmacology of GPCRs 2. real-time assays and imaging 3. Design of FRET/BRET based sensors | 1. GPCR activation 2. arrestin 3. GRKs |
| Onat Filiz Acibadem Mehmet Ali Aydinlar University | TR | wg1, wg2 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| 1. Absence epilepsy rat model 2. Receptors in epilepsy 3. Signaling in epilepsy |
|
| Zugaza José L. Achucarro Basque Center for Neuroscience | ES | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Biochemistry 3. Proteomics |
| 1. cellular functions in health and disease 2. post-translational modifications 3. Recombinant peptides | 1. Small GTPases 2. Glycogen phosphorylase 3. Rare diseases |
| ARGYROU MINAS AGRICULTURAL UNIVERSITY OF ATHENS | GR | wg1, wg3, wg4, wg5 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology 3. 12. Applied Life Sciences and Biotechnology |
| ||
| Noonan Theresa Freie Universität Berlin | DE | wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Scientific computing, simulation and modelling tools 3. Molecular mechanisms of signalling pathways |
| 1. Molecular modelling 2. Computational drug design 3. Structure-based drug design | 1. Allosteric modulation 2. GPCRs 3. Drug design |
| Talagayev Valerij | DE | wg4, wg5 | 1. Biocomputing and molecular computation 2. Organic chemistry 3. Medicinal chemistry |
| 1. GPCR 2. MD Simulations 3. Computational Chemistry |
|
| Kaminski Tim InSingulo AB | SE | wg4 | 1. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds) 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Surface science and nanostructures |
| 1. biosensors 2. single-molecule approaches 3. GPCR | 1. single-molecule biophysics 2. biosensing 3. membrane proteins |
| Mouillac Bernard Institut de Génomique Fonctionnelle, Université Montpellier, CNRS, INSERM | FR | wg1, wg2, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Molecular mechanisms of signalling pathways 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. GPCR 2. expression and purification of membrane proteins 3. cryo-electrom microscopy, NMR, cristallography | 1. G protein-coupled receptors 2. signaling pathways 3. structure, dynamics |
| Gossert Alvar ETH Zürich | CH | wg1, wg3, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| 1. NMR 2. Protein-protein interaction | 1. Drug discovery 2. Molecular interactions |
| Puls Kristina Free University Berlin (Freie Universität Berlin) | DE | wg3, wg4 | 1. Scientific computing, simulation and modelling tools 2. Medicinal chemistry 3. |
| 1. virtual screening, Docking, Molecular dynamic simulations 2. static pharmacophores, dynamic pharmacophores (dynophores) 3. Homology modeling | 1. Kappa Opioid receptor (GPCR) 2. Biased signaling 3. activation mechanism and subsequent signaling pathways |
| Alawa Majed Freie Universität Berlin | DE | wg1, wg2, wg3, wg4 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Rößler Philip ETH Zürich | CH | wg1, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Spectroscopic and spectrometric techniques 3. Macromolecular complexes |
| 1. NMR Spectroscopy 2. Isotope Labelling | 1. Receptor dynamics 2. G protein interactions |
| Denzinger Katrin Freie Universität Berlin | DE | wg1, wg3, wg5 | 1. Scientific computing, simulation and modelling tools 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Cell signalling and signal transduction |
| 1. Molecular Modelling 2. GPCR 3. Functional Selectivity |
|
| Güney Sevin Gazi University | TR | wg1, wg2, wg3, wg4, wg5 | 1. Organ physiology and pathophysiology 2. Cell signalling and signal transduction 3. Organelle biology and trafficking |
| 1. western blot 2. oxidative stress parameters 3. stereotaxic surgery on rodents | 1. opioid peptide receptors 2. cardiopulmonary physiology |
| Güney Sevin Gazi University | TR | wg1, wg2, wg3, wg4, wg5 | 1. Organ physiology and pathophysiology 2. Cell signalling and signal transduction 3. Organelle biology and trafficking |
| 1. western blot 2. oxidative stress parameters 3. stereotaxic surgery on rodents | 1. opioid peptide receptors 2. cardiopulmonary physiology |
| Benkel Tobias ISAR Bioscience | DE | wg1, wg2, wg3, wg4, wg5 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. GPCRs 2. Signal transduction 3. Compartmentalization |
|
| Maccarrone Mauro University of L'Aquila | IT | wg1, wg3 | 1. Biochemistry 2. Molecular mechanisms of signalling pathways 3. Lipid biology |
| 1. Radiometric assays 2. FRAP 3. Enspire | 1. Lipid signalling 2. Endocannabinoids 3. Resolvins |
| Banères Jean-Louis CNRS | FR | wg1, wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Biochemistry 3. Molecular mechanisms of signalling pathways |
| ||
| Scholz Nicole Leipzig University | DE | wg2 | 1. 7. Physiology, Pathophysiology and Endocrinology 2. 6. Cellular and Developmental Biology 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Drosophila | 1. Adhesion GPCR 2. Mechanobiology 3. Physiologie |
| Labani Nedjma Institut Cochin | FR | wg3 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Loebbert Arnelle ETH Zurich | CH | wg1, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Macromolecular complexes 3. Spectroscopic and spectrometric techniques |
| 1. NMR | 1. NMR 2. Arrestin, GRK |
| Verbakel Lina KU Leuven | BE | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Molecular aspects of endocrinology |
| 1. RNAi-mediated knockdown | |
| Kurt Han | SE | wg1, wg3, wg4, wg5 | 1. Scientific computing, simulation and modelling tools 2. Computational biology 3. Machine learning |
| ||
| Al Hamwi Ghazl University of Bonn | DE | wg2, wg4 | 1. Cell signalling and signal transduction 2. Biochemistry 3. Biological chemistry |
| 1. Orphan GPCRs 2. Cell-based assays and HTS 3. Structure-activity relationship |
|
| Ulven Elisabeth Rexen University of Copenhagen | DK | wg3, wg4 | 1. Medicinal chemistry 2. Computational biology 3. Metabolism, biological basis of metabolism-related disorders |
| ||
| Staszewski Marek Medical University of Lodz | PL | wg2, wg3 | 1. Medicinal chemistry 2. Organic chemistry 3. |
| 1. Synhtesis of GPCR ligands 2. In vitro assays | 1. Drug design and synthesis 2. H3R, H1R, M2R/M3R ligands in vitro assays 3. SAR analysis |
| Bernhard Frank Goethe University Frankfurt | DE | wg4 | 1. Protein synthesis, modification, turnover 2. Biochemistry 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Synthetic Biology 2. NMR techniques 3. GPCR ligand interactions | 1. Cell-free synthesis of GPCRs 2. Nanoparticle technologies 3. GPCR engineering |
| Borrega Leire Universidad del País Vasco/Euskal Herriko Unibertsitatea | ES | wg1, wg2, wg3, wg4, wg5 | 1. Molecular mechanisms of signalling pathways 2. Neural cell function, communication and signalling, neurotransmission 3. Cell signalling and signal transduction |
| 1. Selective functionality 2. Kinetics of ligand 3. membrane cholesterol |
|
| Rovira Xavier University of Vic - Central University of Catalonia | ES | wg1, wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Medicinal chemistry 3. Photochemistry |
| 1. Molecular pharmacology 2. Receptor signalling 3. Ligand-receptor interactions | 1. Photopharmacology 2. GPCR 3. Bias Signalling |
| Wilhelm Florian ETH Zürich | CH | wg1, wg3, wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular mechanisms of signalling pathways 3. Macromolecular complexes |
| ||
| Miranda Pastoriza Dario Universidade de Santiago de Compostela | ES | wg1, wg2, wg3 | 1. Medicinal chemistry 2. Biological chemistry 3. Biochemistry |
| 1. Multicomponent Reaction 2. Adenosine 3. Medicinal Chemistry | 1. Drug discovery and development 2. Pharmacology 3. Medicinal Chemistry |
| Campos Prieto Lucía University of Santiago de Compostela | ES | wg2, wg3, wg5 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Rujan Roxana-Maria Coventry University | GB | wg3, wg4, wg5 | 1. Scientific computing, simulation and modelling tools 2. Computational biology 3. Molecular architecture and structure |
| ||
| Liessmann Fabian Leipzig University | DE | wg3, wg4 | 1. Scientific computing, simulation and modelling tools 2. Medicinal chemistry 3. Computational biology |
| 1. Homology modeling 2. Computational Medicinal Chemistry 3. Drug Discovery/Ultra-large library screening | 1. Adhesion GPCRs 2. Computer-Aided Drug Discovery/Design 3. Biased Signaling |
| Jagerovic Nadine Spanish National Research Council | ES | wg3, wg5 | 1. Medicinal chemistry 2. Organic chemistry 3. Theoretical and computational chemistry |
| 1. Cannabinoid Receptors 2. GPCRS-related to the Endocannabinoid System 3. Allosterism and Biased Signaling |
|
| Campbell Adrian Sygnature Discovery | GB | wg3, wg4 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Ramos Sofia Universidade Lusófona | PT | wg1, wg2, wg3, wg4, wg5 | 1. Cell signalling and signal transduction 2. Cell junctions, cell adhesion, cell communication and the extracellular matrix 3. Computational biology |
| ||
| Laboute Thibaut University of Tours | FR | wg1, wg2, wg3 | 1. Cell signalling and signal transduction 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Neural cell function, communication and signalling, neurotransmission |
| 1. BRET, FRET, HTRF, and other sensors 2. cell biology 3. mice behavioural assays | 1. GPCRs 2. Nanobody 3. Neurosciences |
| Andújar Antonio University of Santiago de Compostela | ES | wg2, wg3 | 1. Medicinal chemistry 2. Theoretical and computational chemistry 3. Biological chemistry |
| ||
| ERGUN Sercan Ondokuz Mayıs University | TR | wg2 | 1. Molecular mechanisms of signalling pathways 2. Non-coding RNAs 3. Epigenetics and gene regulation |
| 1. Cancer signalling pathways 2. Epigenetics 3. Drug resistance |
|
| Wieser Mara Paul Scherrer Institut | CH | wg1, wg2, wg3 | 1. 2. 3. |
| ||
| Kahlous Nour Aldin Uppsala University | SE | wg1, wg2, wg3, wg4 | 1. 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| 1. Drug discovery 2. Molecular dynamics 3. FEP |
|
| Walker Abigail Imperial College London | GB | wg1, wg2, wg3 | 1. Molecular aspects of endocrinology 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Macromolecular complexes |
| 1. GPCR 2. Reproduction 3. Super-resolution |
|
| Kopanchuk Sergei University of Tartu | EE | wg2, wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| 1. Fluorescence techniques (FI/FRET, FL, FA) 2. Microscopy techniques (TIRF, FCS, FLIM/TGL) 3. Kinetic modelling | 1. Ligand binding kinetics 2. Single-molecule microscopy 3. Peptides and proteins GPCRs |
| Bergkamp Nick Vrije Universiteit Amsterdam | NL | wg1, wg2 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| ||
| Kniazeff Julie CNRS, University of Montpellier | FR | wg1, wg3 | 1. Molecular mechanisms of signalling pathways 2. Macromolecular complexes 3. Cell signalling and signal transduction |
| ||
| Olechwier Agnieszka Paul Scherrer Institute | CH | wg1, wg2, wg3, wg4, wg5 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Cell signalling and signal transduction |
| ||
| Singh Rajiv Okinawa Institute of Science and Technology, Japan | wg1, wg2, wg3, wg4, wg5 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Imaging for medical diagnosis |
| 1. CryoEM and XRD 2. Molecular Biology and Biochemistry 3. Cell Signaling and Pharmacology | 1. Chemoreceptors 2. CryoEM 3. Crystal Structure |
|
| Simon Katharina University of Bonn | DE | wg2, wg3 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Van den Driest Lisa University of Strathclyde | GB | wg1, wg2, wg3, wg4, wg5 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Qi Chao ETH Zurich | CH | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Biochemistry 3. 1. Mathematics (applications in science and industry) |
| 1. adenylyl cyclase |
|
| Guixà-González Ramon Paul Scherrer institute | CH | wg1, wg3 | 1. Scientific computing, simulation and modelling tools 2. 1. Mathematics (applications in science and industry) 3. Bioinformatics |
| 1. Molecular dynamics simulations 2. Structural bioinformatics 3. Molecular modeling | 1. GPCR-lipid interactions 2. GPCRs activation mechanism 3. GPCR-G protein recognition |
| Novikoff Aaron Helmholtz-Zentrum München | DE | wg1, wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular mechanisms of signalling pathways 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. GLP-1 2. GPCR | 1. Drug-development optimization 2. Dynamic Intracellular Signalling |
| Mahardhika Andhika University of Bonn | DE | wg2, wg4 | 1. Medicinal chemistry 2. Molecular mechanisms of signalling pathways 3. 1. Mathematics (applications in science and industry) |
| 1. Orphan GPCRs 2. Tool compounds 3. Structure-activity relationship |
|
| PANNEELS Valerie Paul Scherrer Institute | CH | wg1, wg2, wg3, wg4 | 1. Molecular architecture and structure 2. Spectroscopic and spectrometric techniques 3. Physics of biological systems |
| 1. GPCR 2. lipid 3. structure |
|
| Bondar Ana-Nicoleta University of Bucharest | RO | wg1, wg2, wg3, wg4, wg5 | 1. Physics of biological systems 2. Molecular architecture and structure 3. Theoretical and computational chemistry |
| 1. graph theory 2. protein reaction mechanism 3. proton transfer | 1. hydrogen bonding 2. protein conformational dynamics 3. pH sensing |
| Tóth András Dávid Semmelweis University | HU | wg2, wg4 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. BRET 2. fluorescent imaging 3. signaling assays | 1. GPCRs 2. biased signaling 3. arrestins |
| Collu Gabriella Paul Scherrer Institut-ETH Zurich | CH | wg1, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Biochemistry 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. cryo-EM 2. membrane protein | |
| Fernandez-Recio Juan Consejo Superior de Investigaciones Científicas (CSIC) | ES | wg1, wg4 | 1. Computational biology 2. Macromolecular complexes 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Protein-protein docking 2. Binding energy calculation 3. Structural modeling | 1. Protein-protein interactions 2. Molecular modeling 3. Structural bioinformatics |
| Pan Kylie InterAx Biotech AG and VU Amsterdam | CH | wg2, wg3 | 1. Systems biology 2. Fundamental mechanisms underlying cancer 3. Cell signalling and signal transduction |
| ||
| Lombo Cristian Julius-Maximilians-Universität Würzburg | DE | wg1, wg2, wg3 | 1. Medicinal chemistry 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Cell signalling and signal transduction |
| 1. synthesis 2. assay 3. signaling | 1. biased signaling 2. SAR 3. Networking |
| Zięba Agata Medical University of Lublin | PL | wg2, wg3 | 1. Theoretical and computational chemistry 2. Bioinformatics 3. 3. Computer Science and Informatics |
| ||
| Boardman Andrew University of Cambridge | GB | wg2, wg4, wg5 | 1. Bioinformatics 2. Machine learning 3. Computational biology |
| ||
| Claff Tobias University of Bonn | DE | wg1, wg2 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Macromolecular complexes 3. Fundamental aspects of synthetic biology and chemical biology |
| 1. X-ray crystallography 2. Protein Purification 3. Insect cells and Expression | 1. GPCR X-ray crystallography 2. Oligomerization of GPCRs 3. Adenosine Receptors |
| Scharf Magdalena M. Philipps-Universität Marburg | DE | wg1, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular mechanisms of signalling pathways 3. Scientific computing, simulation and modelling tools |
| ||
| Lavogina Darja University of Tartu | EE | wg1, wg2, wg3 | 1. Biological chemistry 2. Medicinal chemistry 3. Biochemistry |
| ||
| Llavero Bernal Francisco Instituto de Investigación Hospital 12 de Octubre. Madrid. Spain | wg2 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Molecular mechanisms of signalling pathways 3. Glycobiology |
| |||
| Perez Almeria Claudia V. Vrije Universiteit Amsterdam | NL | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. Molecular pharmacology GPCRs 2. Signal transduction 3. Microscopy | 1. GPCR signalling 2. Nanobodies 3. Oncology |
| Podlewska Sabina Maj Institute of Pharmacology Polish Academy of Sciences | PL | wg3 | 1. Medicinal chemistry 2. 1. Mathematics (applications in science and industry) 3. Machine learning |
| 1. molecular modeling 2. machine learning 3. docking | 1. computer-aided drug design 2. machine learning 3. docking |
| Maslov Ivan KU Leuven | BE | wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Spectroscopic and spectrometric techniques 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| ||
| Hogendorf Adam Maj Institute of Pharmacology, Polish Academy of Sciences | PL | wg2, wg3, wg4 | 1. Medicinal chemistry 2. Organic chemistry 3. Chemical reactions: mechanisms, dynamics, kinetics and catalytic reactions |
| 1. serotonin system 2. glutaminergic system 3. psychopharmacology |
|
| Safitri Dewi University of Cambridge | GB | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Metabolism, biological basis of metabolism-related disorders |
| 1. BRET 2. cloning | 1. GPCR 2. metabolic disorder |
| Delemotte Lucie KTH Royal Institute of Technology | SE | wg3 | 1. Physical chemistry of biological systems 2. Biocomputing and molecular computation 3. Bioinformatics |
| 1. Molecular dynamics simulations | |
| Underwood Owen University of Nottingham | GB | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. BRET 2. Fluorescence Correlation Spectroscopy | 1. opioid 2. beta-arrestin2 3. trafficking |
| Pérez-Conesa Sergio Kungliga Tekniksa Hogskolan (KTH) Stockholm | SE | wg3, wg4, wg5 | 1. Biocomputing and molecular computation 2. Theoretical and computational chemistry 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Molecular Dynamics 2. Allosteric Modulation 3. Drug Design | 1. Molecular Dynamics 2. Drug Design 3. Allosteric modulation. |
| Ma Xin Technical University of Denmark | DK | wg3, wg4 | 1. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. 12. Applied Life Sciences and Biotechnology |
| ||
| Patriarchi Tommaso University of Zurich | CH | wg1, wg2, wg3, wg4 | 1. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds) 2. Applied bioengineering, synthetic biology, chemical biology, nanobiotechnology, metabolic engineering, protein and glyco-engineering, tissue engineering, biocatalysis, biomimetics 3. Neural bases of behaviour |
| 1. protein engineering 2. drug screening 3. in vivo imaging | 1. GPCRs 2. neuromodulators 3. neuropeptides |
| Markova Vendula Charles University | CZ | wg2, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. 1. Mathematics (applications in science and industry) |
| 1. opioid receptors 2. TRPV1 3. arrestin |
|
| Dainese Enrico University of Teramo | IT | wg1, wg2, wg3, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Molecular mechanisms of signalling pathways 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Biochemical Metodologies for functional study of enzymes and receptors 2. SAXS, X-ray diffraction, molecular interactions by FRET and label free technologydocking analysis, homology model 3. In vitro imaging by confocal microscopy | 1. Membrane proteins and lipids 2. GPCRs and lipoxygenase system 3. Cell signaling and trafficking |
| Unsal Serbulent Karadeniz Technical University/Middle East Technical University | TR | wg4 | 1. Bioinformatics 2. Machine learning 3. Proteomics |
| 1. Machine Learning 2. Proteomics 3. Bioinformatics | 1. Protein function prediction 2. Protein/Peptide/Antibody Selection/Design 3. Machine/Deep Learning |
| Novotny Jiri Charles University, Faculty of Science | CZ | wg1, wg2, wg3 | 1. Cell signalling and signal transduction 2. Macromolecular complexes 3. Neural cell function, communication and signalling, neurotransmission |
| 1. cell signaling 2. radioligand binding 3. enzyme assays | 1. GPCRs 2. G proteins 3. cytoprotection |
| Garcia Fernandez Maria Dolores Institut de Biologie Structurale | FR | wg2, wg4 | 1. Molecular mechanisms of signalling pathways 2. Applied bioengineering, synthetic biology, chemical biology, nanobiotechnology, metabolic engineering, protein and glyco-engineering, tissue engineering, biocatalysis, biomimetics 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| ||
| YILMAZLAR Alize Bogazici University | TR | wg2 | 1. Molecular mechanisms of signalling pathways 2. Computational biology 3. Cell signalling and signal transduction |
| 1. Neuroscience 2. In silico methods 3. Signal Transduction |
|
| Sahlholm Kristoffer Umeå University | SE | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Psychiatric disorders 3. Medicinal chemistry |
| 1. Live-cell signaling assays 2. Electrophysiology 3. models of antipsychotic efficacy | 1. dopamine receptors 2. antipsychotics 3. structure-activity relationships |
| Gruber Christian Medical University of Vienna | AT | wg1, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Biochemistry 3. Molecular mechanisms of signalling pathways |
| 1. drug discovery 2. signaling 3. natural product | 1. peptide |
| Rajagopal Sudarshan Duke University School of Medicine | wg2 | 1. Molecular mechanisms of signalling pathways 2. Biochemistry 3. Fundamental mechanisms underlying cardiovascular diseases |
| 1. Biased Agonism 2. Chemokine 3. Arrestin |
||
| Wingler Laura Duke University Medical Center | wg3 | 1. Biochemistry 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Applied bioengineering, synthetic biology, chemical biology, nanobiotechnology, metabolic engineering, protein and glyco-engineering, tissue engineering, biocatalysis, biomimetics |
| 1. Ligand pharmacology 2. Protein engineering |
||
| Melkes Barbora Charles University | CZ | wg2, wg4 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Opioid receptor 2. arrestin 3. TRPV1 |
|
| Eiger Dylan Duke University | wg1, wg2, wg3, wg4 | 1. Biochemistry 2. Cell signalling and signal transduction 3. 6. Cellular and Developmental Biology |
| 1. Bioluminescence Resonance Energy Transfer | 1. G Protein Could Receptors 2. Signal Transduction 3. Biased Agonism |
|
| Weber Verena Leibniz institute of food systems biology at TUM | DE | wg1, wg3, wg4, wg5 | 1. Computational biology 2. Molecular mechanisms of signalling pathways 3. Scientific computing, simulation and modelling tools |
| 1. Computer-aided drug design 2. molecular modeling 3. biochemistry |
|
| Bailey Chris University of Bath | GB | wg1, wg2, wg3, wg4 | 1. Neural cell function, communication and signalling, neurotransmission 2. Fundamental aspects of synthetic biology and chemical biology 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Opioids 2. Addiction 3. Electrophysiology | 1. GPCRs 2. Opioids 3. Biased agonists |
| Hoare Samuel Pharmechanics LLC | wg2, wg3, wg4 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| 1. Kinetics 2. Spatiotemporal signaling 3. Systems pharmacology |
||
| Barreto Carlos University of Coimbra | PT | wg4 | 1. Scientific computing, simulation and modelling tools 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Bioinformatics |
| 1. Structural Modeling 2. Molecular Dynamics | 1. GPCR activation 2. GPCR signaling 3. Molecular Dynamics |
| Alenfelder Judith University of Bonn | DE | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. GPCRs 2. G proteins 3. Signal Transduction |
|
| Caffrey Martin Trinity College Dublin | IE | wg1, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Biological chemistry 3. Biochemistry |
| ||
| Velazhahan Vaithish MRC Laboratory of Molecular Biology | GB | wg1, wg2 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Biochemistry 3. Molecular mechanisms of signalling pathways |
| 1. Cryo-EM, NMR, X-ray Crystallography 2. SPR, SEC-MALS 3. Protein engineering | 1. GPCR Structures 2. GPCR Dimers 3. Drug Development |
| Perera Suchi University of Arizona | wg3 | 1. Physical chemistry of biological systems 2. Biological chemistry 3. 1. Mathematics (applications in science and industry) |
| 1. Electronic Spectroscopy 2. Neutron scattering 3. X-ray scattering | 1. Rhodopsin 2. Membrane proteins 3. Neutron scattering |
|
| Annibale Paolo Max Delbrück Center for Molecular Medicine | DE | wg4 | 1. Physics of biological systems 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Fluorescence Microscopy 2. Super-resolution imaging 3. Receptor Oligomerization |
|
| Gómez-Santacana Xavier Institute for Advanced Chemistry of Catalonia (IQAC) - Spanish National Research Council (CSIC) | ES | wg1, wg3, wg4 | 1. Biological chemistry 2. Medicinal chemistry 3. Photochemistry |
| 1. Medicinal Chemistry 2. Photopharmacology 3. Protein labelling | 1. Medicinal Chemistry 2. Photopharmacology 3. Protein labelling |
| Abate Carmen Università degli Studi di Bari | IT | wg3, wg4 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Schihada Hannes Karolinska Institutet | SE | wg1, wg2, wg3, wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. BRET 2. biosensor 3. WNT signaling | 1. orphan GPCRs 2. conformational biosensors 3. signal transduction |
| Pfersdorf Fabian University of Copenhagen | DK | wg1, wg2 | 1. Molecular mechanisms of signalling pathways 2. Biochemistry 3. Macromolecular complexes |
| 1. Purification 2. Signaling 3. Cryo-EM | 1. Signaling 2. Structure 3. Pharmacology |
| van den bor jelle Vrije universiteit amsterdam | NL | wg1, wg2, wg3 | 1. Tissue organisation and morphogenesis 2. Stem cell biology 3. Molecular mechanisms of signalling pathways |
| ||
| Kinsella Gemma TU Dublin | IE | wg3 | 1. Biological chemistry 2. Biocomputing and molecular computation 3. 12. Applied Life Sciences and Biotechnology |
| 1. GPCRs |
|
| Jacobson Kenneth National Institutes of Health | wg2, wg4 | 1. Medicinal chemistry 2. Cell signalling and signal transduction 3. Biochemistry |
| 1. adenosine receptors 2. P2Y receptors 3. P2X receptors |
||
| Mao Jiafei Goethe University of Frankfurt am Main | DE | wg1 | 1. Spectroscopic and spectrometric techniques 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Physics of biological systems |
| 1. NMR 2. dynamics 3. ligand | 1. structure 2. dynamics 3. methodology |
| Pacull Emelyne University of Leipzig | DE | wg1 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Protein synthesis, modification, turnover 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. Cell-Free Synthesis 2. NMR 3. Protein purification | 1. GPCRs 2. Structural Biology 3. Interactions |
| Zaccolo Manuela University of Oxford | GB | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Fundamental mechanisms underlying cardiovascular diseases 3. Macromolecular complexes |
| 1. real-time imaging 2. protein biochemistry | 1. cAMP 2. cGMP 3. cardiac myocyte |
| Paisdzior Sarah Charité Universitaetsmedizin Berlin | DE | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Molecular aspects of endocrinology |
| 1. Signaling pathway Assays 2. Protein protein interaction | 1. Melanocortin 4 receptor 2. Biased signaling 3. GPCR dimerization |
| Myers Benjamin University of Utah School of Medicine | wg1, wg2, wg3, wg4 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| |||
| Pfeil Eva Marie Vrije universiteit Amsterdam | NL | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Cell differentiation, physiology and dynamics |
| 1. G protein coupled receptors 2. Signal transduction mechanisms 3. In vitro cell culture | 1. GPCR signaling 2. Calcium mobilization 3. Viral GPCRs |
| Nathanail Evangelia University of Oxford | GB | wg1, wg2 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Biochemistry 3. Molecular mechanisms of signalling pathways |
| 1. Cell signaling 2. Structure-to-function |
|
| Janetzko John Stanford University | wg1, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Spectroscopic and spectrometric techniques 3. Molecular architecture and structure |
| 1. protein purification 2. protein structure 3. fluorescence spectroscopy | 1. receptor recycling 2. arrestin domain proteins 3. receptor PTMs |
|
| Ripoll Léa UCSF | wg1, wg2, wg3 | 1. Cell signalling and signal transduction 2. Organelle biology and trafficking 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Fluorescence microscopy 2. GPCR signaling 3. Neuronal cultures | 1. Membrane trafficking 2. GPCR signaling 3. Endosomal signaling |
|
| Menet Christel Confo Therapeutics | BE | wg1, wg2, wg3, wg4, wg5 | 1. Medicinal chemistry 2. Biochemistry 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Drug discovery 2. GPCR 3. biology |
|
| Auger Genevieve Marie Universität Leipzig | DE | wg2, wg3, wg4 | 1. Biochemistry 2. Neural cell function, communication and signalling, neurotransmission 3. Protein synthesis, modification, turnover |
| 1. Biochemistry 2. Neurobiology 3. GPCRs |
|
| Kumar G Aditya University of Michigan | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Lipid biology |
| 1. Membrane 2. trafficking 3. GPCRs |
||
| Fischer Tobias Leipzig University | DE | wg1 | 1. Medicinal chemistry 2. Biological chemistry 3. 1. Mathematics (applications in science and industry) |
| 1. chemokines 2. modeling 3. peptides |
|
| Carvalho Sabrina University of Cambridge | GB | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Nogueira Pedro Campinas State University | wg1, wg2, wg3, wg4 | 1. 7. Physiology, Pathophysiology and Endocrinology 2. Metabolism, biological basis of metabolism-related disorders 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Transgenic mouse model 2. Knockdown of gene expression 3. Protein content analysis | 1. Metabolism 2. Neuroscience 3. Neurons and Astrocytes |
|
| Mighell Taylor Centre for Genomic Regulation | ES | wg1, wg3, wg4 | 1. Fundamental aspects of synthetic biology and chemical biology 2. Molecular mechanisms of signalling pathways 3. Biochemistry |
| 1. Massive mutagenesis 2. Double mutant cycle | 1. Massive mutagenesis 2. Allostery 3. Sequence-function |
| Carvalho Sabrina University of Cambridge | GB | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Second messenger assays 2. BRET and NanoBiT technologies 3. Cell-based assays | 1. GPCR intracellular signalling 2. Investigating receptor pharmacology through BRET 3. MoA studies |
| Sanchez hidalgo Marina University of Seville | ES | wg2, wg3 | 1. Food sciences 2. Biological basis of prevention and treatment of infection 3. Immunological mechanisms in disease |
| 1. Natural products 2. Arthritis, Lupus, colitis 3. Autoimmune diseases | 1. Functional foods 2. Inflammation 3. Autoimmune disease |
| Bravo Sergi University of Bonn | DE | wg1, wg2, wg3, wg4 | 1. Biochemistry 2. Biological chemistry 3. Molecular mechanisms of signalling pathways |
| ||
| Ciancetta Antonella University of Ferrara | IT | wg3, wg4, wg5 | 1. Scientific computing, simulation and modelling tools 2. Medicinal chemistry 3. Computational biology |
| 1. Computer-Aided Drug Design 2. Molecular Dynamics 3. Virtual Screening | 1. GPCR Oligomerization/Biased signaling/Allosteric modulation 2. Peptide GPCRs 3. Drug Design |
| Riemens Rick Vrije Universiteit | NL | wg3, wg4 | 1. Medicinal chemistry 2. Organic chemistry 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| ||
| Deckstein Lisa Rheinische Friedrich-Wilhelms-Universität Bonn | DE | wg1, wg2, wg3, wg4, wg5 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. GPCRs 2. AT1 receptor 3. (Flourescence) microscopy |
|
| Lefebvre Thomas Idorsia Pharmaceuticals Ltd | CH | wg1, wg2, wg3, wg4, wg5 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Immunological mechanisms in disease |
| 1. Drug Discovery 2. GPCRs 3. Immuno Oncology | 1. GPCRs 2. In vitro Pharmacology 3. Signaling pathways |
| Karsak Meliha Universitaetsklinikum Hamburg-Eppendorf | DE | wg2, wg3, wg5 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 6. Cellular and Developmental Biology 3. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology |
| 1. Westernblot, FRET, Luminescence, Microscopy 2. in vivo cAMP Measurement in Living Cell 3. Tumor models, in vivo Application, Obesity | 1. GPCRs, CB1, CB2 2. G-Proteins, Adeylate Cyclases 3. Protein-Protein-Interactions |
| Stampelou Margarita National & Kapodistrian University of Athens | GR | wg1, wg2, wg3, wg4, wg5 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Medicinal chemistry 3. Scientific computing, simulation and modelling tools |
| ||
| Liebing Aenne-Dorothea University Leipzig | DE | wg1, wg2 | 1. Biochemistry 2. Molecular mechanisms of signalling pathways 3. Cell signalling and signal transduction |
| 1. GPCR 2. signal tranduction 3. metabolism |
|
| MARIN MONALISA AGRICULTURAL UNIVERSITY OF ATHENS | GR | wg1, wg2, wg3, wg4, wg5 | 1. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds) 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology |
| ||
| Kaafarani Abeer University Libre De Bruxelles | BE | wg1, wg2 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 6. Cellular and Developmental Biology 3. 8. Neuroscience and Neural Disorders |
| 1. GPCRs 2. Signaling Transduction 3. Protein Protection Interactions |
|
| Zięba Agata Medical University of Lublin | PL | wg3 | 1. Theoretical and computational chemistry 2. Medicinal chemistry 3. Proteomics |
| ||
| Karoussiotis Christos Institute of Biosciences and Applications NCSR ''Demokritos'' | GR | wg2, wg3 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| 1. Opioids 2. Signaling of stress related behaviors 3. Autophagy in brain |
|
| Dokumaci Ecem Ludwig-Maximilians-Universität München | TR | wg1, wg2 | 1. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds) 2. Transcriptomics 3. Molecular mechanisms of signalling pathways |
| 1. Microbiology 2. Cloning 3. Toxicology | 1. Molecular signalling 2. Cloning 3. Microbiology |
| Thomas Romy Max-Delbrück-Centrum | DE | wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| ||
| BRELOT Anne Institut Pasteur | FR | wg1, wg3 | 1. Molecular mechanisms of signalling pathways 2. Mechanisms of infection 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. intracellular trafficking 2. single particle tracking 3. ligand binding | 1. Chemokine receptor 2. Oligomerization 3. Conformational targeting |
| Grätz Lukas Karolinska Institutet | SE | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Biochemistry |
| 1. BRET 2. signaling | 1. GPCR signaling 2. Class F GPCRs 3. G proteins |
| Stępnicki Piotr Medical University of Lublin | PL | wg1, wg3, wg4, wg5 | 1. Medicinal chemistry 2. Organic chemistry 3. Biocomputing and molecular computation |
| 1. Medicinal chemistry 2. CNS disorders 3. Molecular modeling |
|
| Haider Raphael Silvanus Universitätsklinikum Jena | DE | wg1, wg2, wg3, wg4 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Molecular mechanisms of signalling pathways 3. Cell signalling and signal transduction |
| 1. BRET and FRET 2. GPCR-arrestin interactions 3. arrestin conformational change | 1. GPCR 2. arrestin 3. cellular signal transduction |
| Lago Fernández Ana | ES | wg2, wg3, wg4 | 1. Medicinal chemistry 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. 8. Neuroscience and Neural Disorders |
| ||
| Winfield Ian Domainex | GB | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. 1. Mathematics (applications in science and industry) |
| 1. GPCR 2. Molecular pharmacology 3. Quantitative pharmacology | 1. GPCRs 2. Molecular pharmacology 3. Biased agonism |
| Van Loy Tom Rega Institute KU Leuven | BE | wg2, wg3, wg4 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Cell signalling and signal transduction 3. Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds) |
| 1. chemokine GPCRs 2. signal transduction 3. GPCR biosensors | 1. chemokine G protein-coupled receptors 2. cell-based assays 3. ligand bias, allosteric modulators |
| De Jonghe Steven KU Leuven | BE | wg3 | 1. Medicinal chemistry 2. Organic chemistry 3. Biological chemistry |
| 1. chemokine GPCR 2. heterocyclic chemistry 3. GPCR small molecule ligands |
|
| Comez Dehan University of Nottingham | GB | wg1, wg2, wg3 | 1. Macromolecular complexes 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| 1. BRET | 1. GPCR-RTK Interaction 2. CXCR4/ACKR3 3. EGFR |
| Goossens Stijn KU Leuven | BE | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Molecular aspects of endocrinology |
| ||
| Parnas Moshe Tel Aviv University | IL | wg2, wg3 | 1. Neural bases of behaviour 2. Sensation and perception 3. Systems neuroscience and computational neuroscience |
| 1. Olfaction learning and memory, valence, habituation 2. Drosophila 3. Neurons and network properties | 1. Physiological roles of GPCR voltage dependence 2. GPCR neuromodulation (noise reduction) of olfactory learning and memory 3. GPCR and odor coding |
| Baltrukevich Hanna Jagiellonian University | PL | wg1, wg2, wg3, wg4, wg5 | 1. Biocomputing and molecular computation 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Scientific computing, simulation and modelling tools |
| 1. Molecular dynamics 2. Molecular modelling 3. Computational chemistry | 1. Molecular dynamics 2. Molecular modelling 3. Cheminformatics |
| SYMEONOF ALEXANDRA NATIONAL CENTER FOR SCIENTIFIC RESEARCH DEMOKRITOS | GR | wg2 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Neural cell function, communication and signalling, neurotransmission |
| ||
| Yalcin Bahat Pinar University of Health Sciences Istanbul Kanuni Sultan Suleyman Hospital | TR | wg1, wg2 | 1. Organ physiology and pathophysiology 2. Molecular aspects of endocrinology 3. Comparative physiology and pathophysiology |
| 1. pain 2. endometriosis 3. chronic pelvic pain | 1. pain 2. endometriosis 3. gynecological disease |
| Wunsch Friederike Marlene Westfälische Wilhelms-Universität Münster | DE | wg2, wg3, wg4 | 1. Theoretical and computational chemistry 2. Medicinal chemistry 3. Cell signalling and signal transduction |
| ||
| Jakubík Jan Fyziologický ústav Akademie věd České republiky | CZ | wg3 | 1. Molecular mechanisms of signalling pathways 2. Neurological disorders 3. Psychiatric disorders |
| 1. ligand binding 2. signalling pathaways | 1. neuropharmacology 2. cholinergic signalling 3. allosteric modulation |
| Kaczor Agnieszka Medical Univesity of Lublin | PL | wg1, wg3, wg4 | 1. Medicinal chemistry 2. Theoretical and computational chemistry 3. Psychiatric disorders |
| 1. computer-aided drug design | 1. drug design 2. CNS disorders 3. molecular modeling |
| Kanev Georgi InterAx Biotech AG | CH | wg1, wg3, wg4, wg5 | 1. Medicinal chemistry 2. Artificial intelligence, intelligent systems, multi agent systems 3. Bioinformatics |
| ||
| Eryilmaz Funda University of Bonn | DE | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. G protein coupled receptors 2. Signal transduction | 1. GPCR signaling 2. G proteins 3. Signal transduction |
| Kahveci Kübra Bogazici University | TR | wg2 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Biocomputing and molecular computation |
| ||
| Paz Castro Alba USC | ES | wg1, wg2, wg3, wg4, wg5 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Molecular mechanisms of signalling pathways |
| 1. High throughput screening 2. Cell culture 3. binding | 1. molecular pathways 2. hits 3. GPCR |
| Weiler Corinna Rheinische Friedrich-Wilhelms-Universität Bonn | DE | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. GPCRs 2. PROTACs 3. Signal transduction |
|
| Somalo Barranco Gloria Institut Cochin | FR | wg2, wg3 | 1. Medicinal chemistry 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| ||
| Gamiz Jorge Innoprot | ES | wg2, wg4 | 1. Molecular mechanisms of signalling pathways 2. Morphology and functional imaging of cells and tissues 3. Cell signalling and signal transduction |
| 1. GPCR screening 2. MSC differentation 3. recombinant cell line development | 1. GPCR screening 2. arrestin 3. reporter genes |
| adam lucy university of nottingham | GB | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. 6. Cellular and Developmental Biology |
| ||
| Rosa Matthew University of Cambridge | GB | wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Applied gene and cell therapies, regenerative medicine 3. Glycobiology |
| ||
| Gorvin Caroline University of Birmingham | GB | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular aspects of endocrinology 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Metabolic GPCRs (e.g. GHSR) 2. CaSR 3. Endocrine receptors |
|
| Rahman Taufiq University of Cambridge | GB | wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| 1. cell based assays, second messenger assays 2. virtual screening, MD simulation 3. electrophysiology | 1. novel ligand design 2. rational drug design 3. structural dynamics relating to function |
| Gollong Grete Universität Würzburg | DE | wg2, wg3 | 1. Medicinal chemistry 2. Organic chemistry 3. Photochemistry |
| ||
| Bous Julien karolinska institutet | SE | wg2 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Molecular mechanisms of signalling pathways 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. CryoEM; single particle analysis 2. soluble and membrane proteins purification 3. Sf9 proteins expression | 1. GPCRs 2. AVP/OT receptors 3. Frizzled receptors |
| Sirbu Alexei Max Delbrück Center for Molecular Medicine | DE | wg2, wg3 | 1. Cell signalling and signal transduction 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. 1. Mathematics (applications in science and industry) |
| ||
| Hoboth Peter Institute of Organic Chemistry and Biochemistry of the Czech Academy of Science and Faculty of Science, Charles University, Prague | CZ | wg1, wg2, wg4 | 1. Organelle biology and trafficking 2. Morphology and functional imaging of cells and tissues 3. Psychiatric disorders |
| 1. Super-resolution microscopy 2. Single-molecule localization microscopy 3. Cell culture and labeling techniques | 1. Advanced optical microscopy 2. Labeling techniques 3. Protein-protein and lipid-protein interactions in signaling organelle biology |
| Hidber Flurin Paul Scherrer Institut | CH | wg1, wg5 | 1. Bioinformatics 2. Machine learning 3. Web and information systems, database systems |
| 1. GPCR / G protein selectivity 2. Graph representations of proteins 3. Applied Machine Learning |
|
| Sen Saumik Paul Scherrer Institute | CH | wg1, wg2, wg3, wg4 | 1. Physical chemistry of biological systems 2. Theoretical and computational chemistry 3. Photochemistry |
| 1. GPCR 2. Rhodopsin 3. Quantum and molecular dynamics |
|
| Jürgenliemke Lars Rheinische Freideich Wilhelms Universität Bonn | DE | wg1 | 1. 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Karsai Noemi University of Nottingham | GB | wg1, wg2, wg3 | 1. Cell signalling and signal transduction 2. Morphology and functional imaging of cells and tissues 3. Cell differentiation, physiology and dynamics |
| 3. Imaging | 1. Cell signalling 2. Biosensors 3. FCS and confocal imaging |
| Déméné Hélène Centre de Biologie structurale, | FR | wg1, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Molecular mechanisms of signalling pathways |
| 1. NMR 2. fluorescence | 1. biased signaling 2. modulation 3. intracellular partner |
| Quast Robert B. Centre de Biologie Structurale (CBS) Montpellier | FR | wg1, wg2, wg3, wg4, wg5 | 1. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 2. Fundamental aspects of synthetic biology and chemical biology 3. Molecular architecture and structure |
| 1. Membrane Proteins 2. Bioorthogonal Protein Labeling 3. Single Molecule FRET | 1. Structural Dynamics 2. Protein Labeling 3. Single Molecule Approaches |
| Díaz Holguín Alejandro University of Uppsala | SE | wg1, wg2, wg3 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Mühle Jonas Paul Scherrer Institut | CH | wg1, wg3, wg4 | 1. Biochemistry 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Macromolecular complexes |
| ||
| Panagiotopoulos Vasilis University of West Attica | GR | wg1, wg3 | 1. Biocomputing and molecular computation 2. Bioinformatics 3. Machine learning |
| ||
| Bowin Carl-Fredrik Karolinska Institutet | SE | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Neural cell function, communication and signalling, neurotransmission |
| ||
| Sedic Mirela The Institute for Anthropological Research | HR | wg1, wg2, wg3, wg4, wg5 | 1. Proteomics 2. Lipid biology 3. Metabolomics |
| 1. cancer 2. anti-cancer drugs 3. enzyme regulation | 1. colon cancer 2. sphingolipids 3. proteomics |
| Muneta Arrate Itziar Unibersity of the Basque Country | ES | wg3 | 1. Molecular architecture and structure 2. Method development in chemistry 3. Chemical instrumentation |
| 1. GPCR 2. Biased agonism 3. Functional selectivity | 1. GPCR 2. biased agonism 3. pharmacology |
| Rzhevska Nataliia Hryhorii Skovoroda University in Pereiaslav | wg4 | 1. Artificial intelligence, intelligent systems, multi agent systems 2. Food sciences 3. Environmental biotechnology |
| 1. AI 2. neuroscience 3. knowledge transfer |
||
| Gattringer Jasmin Medical University of Vienna | AT | wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Cell signalling and signal transduction 3. 9. Immunity and Infection |
| 1. peptides 2. autoimmune diseases 3. drug discovery |
|
| Refsholt Anne ISAR Bioscience GmbH | DE | wg1, wg2, wg3, wg4, wg5 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Arrestin 2. GPCRs 3. Signal transduction |
|
| Cong Xiaojing Institut de génomique fonctionnelle | FR | wg2, wg3, wg4, wg5 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| 1. Membran protein structural dynamics 2. Drug design |
|
| Tomasevic Natasa Medical University of Vienna | AT | wg1, wg3 | 1. Cell signalling and signal transduction 2. Molecular mechanisms of signalling pathways 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Drug discovery 2. Protein-protein interactions 3. GPCR signaling | |
| Funke Pauline Humboldt University, Berlin | DE | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Biochemistry |
| 1. Arrestin interactions 2. Signal transduction |
|
| Kiss Dóra Judit ELKH Research Centre for Natural Sciences, Budapest | HU | wg1, wg3 | 1. Theoretical and computational chemistry 2. Medicinal chemistry 3. Scientific computing, simulation and modelling tools |
| 1. MD 2. QM/MM 3. CADD | 1. GPCRs 2. functional selectivity / biased signaling 3. computer aided drug design |
| Schneider Johannes Friedrich-Alexander-Universität Erlangen-Nürnberg | DE | wg2, wg3 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Medicinal chemistry 3. Molecular mechanisms of signalling pathways |
| 1. Expression 2. Evaluation 3. Purification | 1. Medicinal Chemistry 2. GPCRs |
| Peri Lior The Hebrew University of Jerusalem | IL | wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Biochemistry 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| ||
| Jalševac Florijan Rovira i Virgili University | ES | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Quantitative genetics 3. Fundamental mechanisms underlying ageing |
| 1. qPCR, ELISAS, Electrophoresis 2. Medicine, interactions 3. Experience with Rat models | 1. Signal transduction 2. Enterohormonal regulation 3. Aging effects |
| Cimadevila Marta University of Montpellier | FR | wg1, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Neurological disorders |
| 1. GPCR 2. Internalization 3. FRET |
|
| Walter Deborah Univerity of Antwerp | BE | wg1, wg2, wg3 | 1. Proteomics 2. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 3. Metabolism, biological basis of metabolism-related disorders |
| 1. Mass spectrometry 2. Cellular assays 3. Protein purification | 1. GPCR signaling bias 2. Aging-related mechanisms |
| Abdulrahman Abdulrasheed Olayinka Universite Paris cite (Inserm) | FR | wg2, wg3 | 1. Cell signalling and signal transduction 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Biochemistry |
| 1. Cell culture and transfection 2. BRET 3. Agonist - Receptor interaction | 1. GPCR 2. Melatonin Receptor 3. Mitochondria |
| Cullum Sean University of Nottingham | GB | wg1, wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. G protein-coupled receptors 2. cAMP signalling 3. Bioluminescence resonance energy transfer (BRET) | |
| Jalsevac Florijan Rovira and Virgili University | ES | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Biochemistry 3. Systems biology |
| ||
| Dennis Morgan University of Nottingham | GB | wg1, wg2, wg3, wg4 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Molecular mechanisms of signalling pathways 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. Pharmacology 2. Drug Discovery 3. Bioengineering |
|
| Gusach Anastasiia MRC Laboratory of Molecular Biology | GB | wg1, wg3, wg4 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Molecular architecture and structure 3. Molecular mechanisms of signalling pathways |
| 1. single particle Cryo-EM, crystallography | 1. Novel structures of GPCR obtained by crysllography and single particle Cryo-EM 2. Cryo-EM method development for challenging GPCR targets |
| Tsai Ching-Ju Paul Scherrer Institute | CH | wg1, wg2, wg3, wg4, wg5 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Biochemistry 3. Molecular architecture and structure |
| 1. X-ray crystallography and cryo-EM 2. Membrane protein biochemistry 3. Protein structure determination | 1. Signalling 2. Protein-protein interactions 3. Machine learning |
| Chen Yao University Medical Center Hamburg-Eppendorf | DE | wg1, wg2, wg3, wg4 | 1. 7. Physiology, Pathophysiology and Endocrinology 2. 8. Neuroscience and Neural Disorders 3. 10. Applied Medical Technologies, Diagnostics, Therapies and Public Health |
| 1. GPCR 2. Glioblastoma 3. signal transduction |
|
| Chen Yao University Medical Center Hamburg-Eppendorf | DE | wg1, wg2, wg3, wg4 | 1. 7. Physiology, Pathophysiology and Endocrinology 2. 8. Neuroscience and Neural Disorders 3. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics |
| 1. GPCR 2. Glioblastoma 3. Cannabinoids |
|
| Merten Nicole University of Bonn | DE | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Biochemistry |
| 1. GPCR 2. G protein 3. Protac |
|
| Chorianopoulou Anna National Kapodistrian University of Athens | GR | wg1, wg2, wg3 | 1. Pharmacology and pharmacogenomics (including drug discovery and design) 2. Scientific computing, simulation and modelling tools 3. Molecular mechanisms of signalling pathways |
| ||
| Tejero Oliver Paul Scherrer Institut | CH | wg1, wg2, wg3 | 1. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 2. Biochemistry 3. Molecular mechanisms of signalling pathways |
| ||
| Matthees Edda S. F. University Hospital Jena | DE | wg1, wg2, wg3, wg4 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| 1. BRET/FRET-based sensors 2. GPCR-arrestin interaction 3. Conformational changes | 1. GPCR regulation 2. GRKs 3. Arrestins |
| Gulliver Chloe University of Glasgow | GB | wg1, wg2, wg3 | 1. Fundamental mechanisms underlying cancer 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| ||
| Brand Thomas Imperial College London | UK | wg1, wg2 | 1. Cell signalling and signal transduction 2. Organ physiology and pathophysiology 3. Fundamental mechanisms underlying cardiovascular diseases |
| 1. Protein-protein interactio 2. mouse, zebrafish 3. Cyclic AMP | 1. Poepeye domain containing genes 2. cardiac pacemaking 3. cqrdiac myocytes |
| Chewle Surahit Zuse Institute Berlin | wg1, wg2, wg4 | 1. Scientific computing, simulation and modelling tools 2. Bioinformatics 3. Sensation and perception |
| 1. Molecuar dynamics 2. Computational molecular design 3. Mutations | 1. Mu opioid receptor 2. Biased ligand 3. allosteric signal transduction |
|
| Tomas Alejandra Imperial College London | UK | wg1, wg2, wg3, wg4, wg5 | 1. 6. Cellular and Developmental Biology 2. Organelle biology and trafficking 3. Cell signalling and signal transduction |
| 1. islet biology 3. T2D mouse models | |
| Jadhav Kirtikumar Bhaskarrao University of Vienna, Vienna, Austria | AT | wg2, wg3, wg4 | 1. Biological chemistry 2. Medicinal chemistry 3. Fundamental aspects of synthetic biology and chemical biology |
| 1. Peptides, small molecules, amino acids 2. GPCRs 3. Recombinant protein synthesis | 1. synthetic peptides and proteins 2. small molecule drug discovery 3. GPCRs |
| Kayser Charlotte Max Delbrück Center for Molecular Medicine | DE | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Cell signalling and signal transduction 3. Biochemistry |
| ||
| Spiess Katja University of Copenhagen | DK | wg2, wg3, wg4 | 1. Infectious diseases 2. Cell junctions, cell adhesion, cell communication and the extracellular matrix 3. Mechanisms of infection |
| 1. G protein-coupled receptors (GPCRs) 2. Drug development 3. RNA and DNA viruses | 1. Novel anti-viral drugs 2. adhesion GPCRs 3. Virus exploited- and encoded GPCRs |
| Liem Nicolas Humboldt-University of Berlin | DE | wg1, wg3 | 1. Fundamental aspects of synthetic biology and chemical biology 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| 1. membrane-bound enzymes, enzyme characterization, membrane protein purification 2. electrophysiology, time-resolved spectroscopy 3. membrane protein purification, protein engineering | 1. Optogenetics 2. Mechanisms of enzyme regulation 3. Structure-function relationship |
| Zaetta Giorgia Pharmacelera | IT | wg4 | 1. Medicinal chemistry 2. Scientific computing, simulation and modelling tools 3. Theoretical and computational chemistry |
| 1. Computer Aided Drug Design 2. Medicinal Chemistry |
|
| Weinmann Christian ETH Zurich | CH | wg2, wg3 | 1. Molecular mechanisms of signalling pathways 2. Spectroscopic and spectrometric techniques 3. Biochemistry |
| 1. Regulation of Signal Transduction 2. Cell Assay Development 3. High Throughput Screening |
|
| Garcia-Marcos Mikel Boston University School of Medicine | wg1, wg2, wg3, wg4 | 1. Cell signalling and signal transduction 2. Cytoskeleton and cell behaviour 3. Neural cell function, communication and signalling, neurotransmission |
| 1. Signaling assays 2. Reconstituted purified systems 3. Bioluminescence energy resonance energy trasnfer | 1. G protein regulation 2. Tool development 3. Molecular basis of disease |
|
| Matricon Pierre Sosei Heptares | GB | wg3, wg4, wg5 | 1. Theoretical and computational chemistry 2. Computational biology 3. Medicinal chemistry |
| 1. Structure-Based Drug Discovery |
|
| Pérez-Hernández Guillermo Charité -- Universitätsmedizin Berlin | DE | wg1, wg3, wg4 | 1. Theoretical and computational chemistry 2. Scientific computing, simulation and modelling tools 3. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) |
| ||
| Llebaria Amadeu MCS, Institute of advanced Chemistry of Catalonia CSIC | ES | wg1, wg3, wg4 | 1. Medicinal chemistry 2. Biological chemistry 3. Biochemistry |
| 1. medicinal chemistry 2. photopharmacology | 1. drug discovery 2. chemical biology 3. molecular design |
| Shchepinova Maria Imperial College London | GB | wg1, wg2, wg3, wg4, wg5 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 5. Genetics, ’Omics’, Bioinformatics and Systems Biology 3. 6. Cellular and Developmental Biology |
| 1. GPCR 2. metabolic 3. proximity |
|
| Demirbaş Berkay Middle East Technical University | TR | wg1, wg2, wg3, wg4 | 1. Organelle biology and trafficking 2. Molecular mechanisms of signalling pathways 3. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) |
| ||
| Garg Jaspal Heidleberg University | DE | wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 6. Cellular and Developmental Biology 3. 7. Physiology, Pathophysiology and Endocrinology |
| ||
| Ciruela Francisco Universitat de Barcelona | ES | wg1, wg3, wg4 | 1. 8. Neuroscience and Neural Disorders 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Molecular mechanisms of signalling pathways |
| 1. GPCR neuropharmacology 2. Schizophrenia and Parkinson models 3. Photopharamacology drugs | 1. GPCR heteromerization 2. Photopharmacology drug discovery 3. Neurodegeneration and Psychiatry |
| Pinheiro Inês University of Geneva | CH | wg1, wg2 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 6. Cellular and Developmental Biology 3. 12. Applied Life Sciences and Biotechnology |
| 1. Western 2. Trafficking 3. Chemokine | |
| Ferreira da Rocha Branco Camila Raquel University of Geneva | CH | wg1, wg2, wg3, wg4, wg5 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 6. Cellular and Developmental Biology 3. Biocomputing and molecular computation |
| 1. Cell-based assays-BRET-based 2. Microscopy | 1. Pharmacology 2. Chemokine receptors 3. Chemokine analogs |
| Ben-Chaim Yair Open University of Israel | IL | wg3 | 1. Cell signalling and signal transduction 2. Neural cell function, communication and signalling, neurotransmission 3. Molecular mechanisms of signalling pathways |
| 1. Electrophysiology 2. Xenopus oocytes | 1. GPCRs 2. voltage dependence |
| Jack Christine University of Aberdeen | GB | wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Molecular mechanisms of signalling pathways 3. Pharmacology and pharmacogenomics (including drug discovery and design) |
| 1. Endocytosis 2. Post-endocytic trafficking |
|
| SOUNIER Remy Institut de Génomique Fonctionnelle | FR | wg1, wg3, wg4 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. Structural biology and its methodologies (e.g. crystallography, cryo-EM, NMR and new technologies) 3. Biochemistry |
| 1. NMR | |
| Vogt Hannah Friedrich-Alexander-University Erlangen-Nürnberg | DE | wg1, wg2 | 1. Medicinal chemistry 2. Cell signalling and signal transduction 3. Molecular mechanisms of signalling pathways |
| ||
| De Groof Timo Vrije Universiteit Brussel | AL | wg1, wg2, wg3 | 1. 4. Molecular Biology, Biochemistry, Structural Biology and Molecular Biophysics 2. 6. Cellular and Developmental Biology 3. 12. Applied Life Sciences and Biotechnology |
| 1. Signal transduction 2. Nanobody development 3. GPCR pharmacology | 1. GPCR signal transduction 2. Nanobody development |
| D'Uonnolo Giulia Luxembourg Institute of Health | LU | wg2 | 1. Molecular mechanisms of signalling pathways 2. Molecular genetics, reverse genetics, forward genetics, genome editing 3. Cell signalling and signal transduction |
| 1. bioluminescence 2. CRISPR | 1. signal transduction 2. cell migration 3. genome editing |
| LABANI Nedjma Institut Cochin | FR | wg1, wg2, wg3, wg4, wg5 | 1. 1. Mathematics (applications in science and industry) 2. 1. Mathematics (applications in science and industry) 3. 1. Mathematics (applications in science and industry) |
| ||
| Mathiasen Signe University of Copenhagen | DK | wg1, wg2, wg4 | 1. Molecular mechanisms of signalling pathways 2. Molecular biophysics (e.g. single-molecule approaches, bioenergetics, fluorescence) 3. Cell signalling and signal transduction |
| 1. single molecule microscopy 2. adhesion GPCR signal transduction 3. adhesion GPCR cell-cell connectivity | 1. ADGRL3 2. adhesion GPCR 3. GPCR signal transduction |
| Delaitre Céline Université de Lorraine | FR | wg1 | 1. Cell signalling and signal transduction 2. Pharmacology and pharmacogenomics (including drug discovery and design) 3. Neurological disorders |
|
