WG1 + WG2 survey – physiological systems

Physiological systems of interest:Cell, tissue, organ type of interest:Cellular responses of interest:Pathological states of interest:Last name:First name:Contact e-mail:Institution/University:Country:
Nervous system;Endocrine system;Immune systemPituitary, hypothalamusSecretion, tumorigenesisCancer, pituitary tumors, gigantismAbboudDayanaUniversity of LiegeBelgium
Nervous systemBrainCNS diseases in which glutamatergic transmission is disruptedAcherFrancineUniversity of Paris/CNRSFrance
Endocrine system;Reproductive systemGnRH neurons, Kiss-peptin and KDY neurons, gonadotrophs, Leydig cells, granulosa and teka cells, spermatozoaMitochondrial dynamics, fertilization, reproductive hormones homeostasisPTSD, insulin resistance, POCSAndricSilvanaUniversity of Novi Sad Faculty of SciencesSerbia
Endocrine system;Gastrointestinal systemIntestineEnterohormone secretionFood intake disruptionArdevolAnnaUniversitat Rovira i VirgiliSpain
Endocrine system;Immune system;Gastrointestinal systemGastrointestinal tissuesEndocrine system, intestinal system, GPCR responses, intestinal responsesHealthy and diseased (IBS, allergy, diabetes)Bastiaan-NetShannaWageningen UR; Food & Biobased ResearchNetherlands
HEK293, CHOSecond messenger production, cell morphological changes, receptor desensitizationBenkelTobiasUniversity of BonnGermany
Endocrine systemPVN, ARCObesityBiebermannHeikeCharite University Medicine BerlinGermany
Nervous system;Endocrine systemcAMP, FRETBirgulNeclaUniversity of BogaziciTurkey
Nervous system;Immune systemPancreas, brainExpression of GLI transcription factorCancerBlanco-CanosaJuan BautistaInstitute for Advanced Chemistry of Catalonia (IQAC-CSIC)Spain
Nervous system;Endocrine system;Immune system;Reproductive systemGonads and brainSteroid secretionInfertility and autismBozonVeroniqueINRAe and University of ToursFrance
Cardiovascular systemBiased signalingHypertensionChabbertMarieCNRSFrance
Nervous systemTissue Cultures all types, Brain regionsReceptor activation, Desensitization, Autophagy, Endosomal signalingStress, Pain, Tolerance, Addiction, DepressionGeorgoussiZafiroula (Iro)Institute of Biosciences and Applications/National Centre for Scientific Research "Demokritos"Greece
Nervous system;Endocrine system;Immune systemBloodProliferation, immune functionAutoimmune disordersGruberChristianMedical University of ViennaAustria
Nervous system;Endocrine systemBrain, PancreasG protein activation and Arrestin recruitmentPsychiatryHauserAlexanderUniversity of DenmarkDenmark
Cardiovascular system;Immune systemDifferent inflamed cellInflammatory cellsInflammatory diseaseHoxhaMalvinaCatholic University Our Lady of Good CounselAlbania
Endocrine system;Cardiovascular systemSmooth muscle cellsG-protein activationHypertensionHunyadyLaszloResearch Centre for Natural SciencesHungary
Endocrine system;Reproductive systemcAMP, PKA, gene expression, steroidogenesisInfertilityJean-AlphonseFredericCNRSFrance
Nervous system;Endocrine system;Immune systemBrain, PBMC, SH-SY5YAutophagy and mitophagy, inflammationNeurodegenerative disorders, including Parkinsonism, Alzheimer's Disease, InflammationKanBekiAcibadem UniversityTurkey
Endocrine systemGBM (Brain); Colo-rectalKinsellaGemmaTU DublinIreland
Structure-based workKolbPeterPhilipps-University MarburgGermany
Nervous system;Cardiovascular system;Respiratory systemAnyAnyParkinson, cancerKolocourisAntoniosNational and Kapodistrian University of Athens, PharmacyGreece
Nervous systemBraincAMP responseNeurodegenerative diseases and addictionLaasfeldTonisUniversity of TartuEstonia
Nervous system;Endocrine system;Blood;Immune system;Gastrointestinal system;Urinary system;Reproductive systemPituitary glandRegulation of gene expressionEndocrine or immune systems disordersLatekDorotaUniversity of WarsawPoland
Immune system;Reproductive systemLiessmannFabianInstitute for Drug DiscoveryGermany
Nervous system;Gastrointestinal systemIdemAll of those related to GHSR-1aLouetMaximeUniversity of MontpellierFrance
Nervous system;Cardiovascular system;Immune system;Gastrointestinal system;Respiratory systemDiversecAMP, Ca2+, beta-arrestin recruitment, microscopically visible changesInflammation, neuroinflammation, infection, cancerMuellerChristaUniversity of BonnGermany
Endocrine system;Cardiovascular systemBeta-arrestin, cAMPCancerNemecKatarinaMDC BerlinGermany
Cardiovascular systemBlood tissueFRETClotting issuesOlgacAbdurrahmanGazi UniversityTurkey
Nervous system;Immune systemBrain, spleen, peripheral blood mononuclear cells, microgliaAutophagy, cellular metabolism (mitochondria), Endosomal traffickingAlzheimer's disease, Parkinson's disease, inflammationOz-ArslanDevrimAcibadem UniversityTurkey
Nervous systemOlfactory systemParnasMosheTel Aviv UniversityIsrael
Immune systemCalcium mobilisation, cell proliferation, cancer growthCancerPfeilEvaVrije Universiteit AmsterdamNetherlands
Cardiovascular system;Immune systemVascular cells (endothelial and smooth muscle cells), T cells and other immune cellsCardiovascular disease, Immune diseaseRajagopalSudarshanDuke University School of MedicineUSA
Nervous system;Endocrine system;Cardiovascular system;Reproductive systemMammalian cell cultures, primary cell culturesActivation/inhibition of cAMP (response to measure for all G proteins (using modified proteins))So far no direct studies involvedRinkenAgoUniversity of TartuEstonia
Nervous systemBrainNeurodegenerationScarpaMiriamUniversity of GlasgowUnited Kingdom
Immune systemDendritic Cells, Keratinocytes, Skin, Lymph NodesMigrationViral infections and CancerSchlechtGeraldineUniversity Paris-SaclayFrance
Immune systemImmune system mouse/humanCell migrationThelenMarcusInstitute for Research in Biomedicine, Universita della Svizzera ItalianaSwitzerland
Normal melanocyte, astrocyte, epithelia,fibroblast vs. Melanoma, glioblastoma, carcinoma, sarcoma. iPSCsProliferation, apoptosis, necroptosis, glycolysis, oxidative phosphorylation/mitochondrial respiration,CancerUldrijanStjepanMasaryk UniversityCzech Republic
Nervous system;Endocrine systemVanden BroeckJozefKU LeuvenBelgium
Blood;Immune systemNK cells, T cells, macrophages, dendritic cells; various kinds of tumour cells and tumour cell linesNK cell or cytotoxic T cell response to cancer, i.e., killing of tumour cellsCancerVanekOndrejCharles University, Faculty of ScienceCzech Republic
Nervous systemAstrocytes, neurons, brain tissue, brain/CNSMetabolism, exocytosis, morphologyNeurodegeneration (brain aging), neuroinflammation, brain edema, epilepsy, ishemiaVardjanNinaUniversity of Ljubljana, Faculty of MedicineSlovenia
Nervous system;Cardiovascular systemBrainSeizuresVaversEdijsLatvian Institute of Organic SynthesisLatvia
Endocrine system;Reproductive systemVreclMilkaUniversity of Ljubljana Slovenia
Cardiovascular system;Blood;Immune systemWinglerLauraDuke UniversityUnited States
Nervous system;Immune systemProteostasisDementia, Alzheimer's disease, epilepsyZerovnikEvaJosef Stefan InstituteSlovenia

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COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation.

COST Action CA18133

All cells face the vital challenge of sensing their environments and responding in appropriate ways. How are different signalling pathways activated and modulated in precise and reproducible ways? Filling this gap in knowledge is absolutely necessary to advance the next generation of pharmaceutical drugs.

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